- Radiomics and Machine Learning in Medical Imaging
- Liver Disease Diagnosis and Treatment
- AI in cancer detection
- Hepatitis B Virus Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- MRI in cancer diagnosis
- Pancreatic and Hepatic Oncology Research
- Ultrasound Imaging and Elastography
- Breast Cancer Treatment Studies
- Liver Disease and Transplantation
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Viral-associated cancers and disorders
- Advanced X-ray and CT Imaging
- Adenosine and Purinergic Signaling
- Photoacoustic and Ultrasonic Imaging
- Histiocytic Disorders and Treatments
- Spine and Intervertebral Disc Pathology
- Advanced Radiotherapy Techniques
- Health Systems, Economic Evaluations, Quality of Life
- Organ Transplantation Techniques and Outcomes
- Tumors and Oncological Cases
- Nanoplatforms for cancer theranostics
- Testicular diseases and treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
Zhejiang University
2008-2024
Maastricht University
2023-2024
First Affiliated Hospital Zhejiang University
2021-2024
Second Hospital of Anhui Medical University
2024
Anhui Medical University
2024
Shandong Institute of Automation
2021-2022
Chinese Academy of Sciences
2021-2022
National Natural Science Foundation of China
2021
University of Chinese Academy of Sciences
2021
82th Hospital of Pla
2015
Abatract Background Neoadjuvant chemotherapy (NAC) can downstage tumors and axillary lymph nodes in breast cancer (BC) patients. However, response to NAC are not parallel vary among This study aims explore the feasibility of deep learning radiomics nomogram (DLRN) for independently predicting status node metastasis (LNM) after NAC. Methods In total, 484 BC patients who completed from two hospitals (H1: 297 training cohort 99 validation cohort; H2: 88 test cohort) were retrospectively...
Accurate and non-invasive diagnosis of pancreatic ductal adenocarcinoma (PDAC) chronic pancreatitis (CP) can avoid unnecessary puncture surgery. This study aimed to develop a deep learning radiomics (DLR) model based on contrast-enhanced ultrasound (CEUS) images assist radiologists in identifying PDAC CP.Patients with or CP were retrospectively enrolled from three hospitals. Detailed clinicopathological data collected for each patient. Diagnoses confirmed pathologically using biopsy surgery...
Endosonographers are highly dependent on the diagnosis of pancreatic ductal adenocarcinoma (PDAC). The objectives this study were to develop a deep-learning radiomics (DLR) model based endoscopic ultrasonography (EUS) images for identifying PDAC and explore its true clinical benefit.A retrospective data set EUS that included benign lesions was used as training cohort (N = 368 patients) DLR model, prospective test 123 validate effectiveness model. In addition, seven endosonographers performed...
Neoadjuvant chemotherapy (NAC) is the primary method to reduce burden of tumor and metastasis; in treatment breast cancer, it may provide additional opportunities for breast-conserving surgery. Preoperative assessment pathological complete response (PCR) NAC important developing individualized approaches predicting patient prognosis. Compared magnetic resonance imaging (MRI) mammography, ultrasonography (US) has advantages simplicity, flexibility, real-time imaging. Moreover, does not...
Rosai-Dorfman disease (RDD) is an idiopathic histiocytic proliferation affecting the lymph nodes. Isolated intracranial RDD rare and usually appears as a well-defined, dural-based lesion without lymphadenopathy. The clinical radiological features of are similar to meningioma. Histopathology immunohistochemistry essential for definitive diagnosis. This report 43-year old male with isolated RDD, which manifested suprasellar clinical, pathological aspects discussed within context review...
Abstract Purpose To explore the usefulness of liver stiffness measurements (LSMs) by sound touch elastography (STE) and quantification (STQ) in chronic hepatitis B (CHB) patients for staging fibrosis. Methods This prospective multicenter study recruited normal volunteers CHB between May 2018 October 2019. The underwent LSM STE supersonic shear imaging (SSI) or STQ acoustic radiation force impulse (ARFI). biopsy both STE/STQ. areas under receiver operating characteristic curves (AUCs)...
Abstract Objectives This study aimed to develop a quantitative intratumoral heterogeneity (ITH) model for assessing the risk of early recurrence (ER) in pre‐treatment multimodal imaging hepatocellular carcinoma (HCC) patients undergoing ablation treatments. Methods multi‐centre enrolled 633 HCC who underwent ultrasound‐guided local between January 2015 and September 2022. Among them, 422, 85, 57 69 radiofrequency (RFA), microwave (MWA), laser (LA) irreversible electroporation (IRE) ablation,...
Abstract Background Not only should resistance to neoadjuvant chemotherapy (NAC) be considered in patients with breast cancer but also the possibility of achieving a pathologic complete response (PCR) after NAC. Our study aims develop 2 multimodal ultrasound deep learning (DL) models noninvasively predict and PCR NAC before treatment. Methods From January 2017 July 2022, total 170 were prospectively enrolled. All underwent examination (grayscale 2D elastography) We combined...
This study aims to clarify the potential mechanism of modified Bu-Shen-Huo-Xue decoction (MBSHXD) in treating intervertebral disc degeneration (IDD) with methods network pharmacology and molecular docking.An MBSHXD IDD-related common target gene set was established through TCMSP, UniProt, two disease databases. GO KEGG enrichment analysis protein-protein interaction (PPI) networks were performed R platform STRING discover mechanism. Molecular docking between active ingredients core genes is...
BACKGROUND Ultrasonography-guided percutaneous drainage for pancreatic fluid collections is associated with a high recurrence rate and endoscopic ultrasonography (EUS)-guided valuable approach. Our aim was to compare the efficacy safety of EUS-guided recurrent collections. MATERIAL AND METHODS A retrospective analysis percutaneous-guided procedures drainages at single tertiary care center between February 2017 May 2018 performed. Treatment success, adverse events, recurrence, need surgery,...
Objectives To evaluate the performance of liver stiffness (LS) and spleen (SS) by using sound touch elastography (STE) technique compare with those splenic index, aspartate transaminase‐to‐platelet ratio index (APRI), fibrosis‐4 (FIB‐4) King's score combined models for diagnosing staging fibrosis in chronic hepatitis B (CHB). Methods One hundred patients CHB underwent STE serological tests. LS SS values were measured technique, was calculated. Staging determined biopsy. Correlations between...
Purpose This study aimed to investigate the technical efficiency and therapeutic response of fusion imaging (considered as virtual navigation) between contrast-enhanced ultrasound (CEUS) computed tomography/magnetic resonance (CECT/CEMRI) for guidance radiofrequency ablation (RFA) in patients with residual hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE).Methods For this prospective study, 98 HCC lesions TACE treatment were enrolled June 2017 December...
Objective To investigate the safety and efficacy of laparoscopic splenectomy (LS) in patients with hepatitis B virus (HBV)-related cirrhotic, portal hypertension splenomegaly. Methods Clinical data 10 HBV-related splenomegaly undergoing LS 105th Hospital Chinese People's Liberation Army between September 2008 December 2014 were retrospectively analyzed. Among patients, 4 males 6 females, age ranging from 28 to 65 years old median 48 old. One case was mild 9 moderate splenomegaly. The...