A5101919830- Forest Insect Ecology and Management
- Insect and Pesticide Research
- Insect Resistance and Genetics
- Entomopathogenic Microorganisms in Pest Control
- Plant biochemistry and biosynthesis
- Insect Pest Control Strategies
- Insect and Arachnid Ecology and Behavior
- Physiological and biochemical adaptations
- Heat shock proteins research
- Adrenal and Paraganglionic Tumors
- RNA Research and Splicing
- Molecular Biology Techniques and Applications
- Lung Cancer Treatments and Mutations
- Sexual Differentiation and Disorders
- Insect-Plant Interactions and Control
- Extracellular vesicles in disease
- Protein purification and stability
- Fungal Biology and Applications
- Bioenergy crop production and management
- Genomics and Chromatin Dynamics
- Cancer-related Molecular Pathways
- Ginkgo biloba and Cashew Applications
- Drug Solubulity and Delivery Systems
- Metabolism and Genetic Disorders
- Nuclear Receptors and Signaling
Nanjing Forestry University
2019-2025
Nanjing Agricultural University
2024
Zhejiang University
2023-2024
Yili Friendship Hospital
2020-2021
Novartis (Canada)
2018
Montreal Neurological Institute and Hospital
2018
Guangdong Laboratory Animals Monitoring Institute
2017
Northwest A&F University
2015
Endosonographers are highly dependent on the diagnosis of pancreatic ductal adenocarcinoma (PDAC). The objectives this study were to develop a deep-learning radiomics (DLR) model based endoscopic ultrasonography (EUS) images for identifying PDAC and explore its true clinical benefit.A retrospective data set EUS that included benign lesions was used as training cohort (N = 368 patients) DLR model, prospective test 123 validate effectiveness model. In addition, seven endosonographers performed...
The ambrosia beetle Euwallacea interjectus Blandford (Coleoptera: Curculionidae: Scolytinae) has recently emerged as a pest in Chinese poplar plantations, causing significant economic losses through damage to host trees association with its mutualistic fungus Fusarium populicola. This study evaluated the biocontrol potential of Beauveria bassiana strain B-BB-1, Serratia marcescens B-SM-1, metabolite prodigiosin, and two ectoparasitic mites, Pyemotes moseri zhonghuajia. B. exhibited lethality...
Parkinson's disease (PD) is a degenerative disorder of the central nervous system mainly affecting motor system. Presently, there no effective and safe drug to treat patients with PD. Ginkgo biloba extract (GBE), obtained from leaves tree, complex mixture ingredients primarily containing two active components: flavonoids terpenoids. In this study, we investigated effects GBE on A53T α-synuclein transgenic mice, PD model that has better simulated progression than other models such as...
Abstract Euwallacea interjectus, a recently discovered pest in poplar plantations, poses significant economic threat due to its role causing widespread tree mortality. This pest's cryptic behaviour has hindered research and control efforts, making laboratory rearing valuable tool for studying development biology. We investigated the period biological characteristics of E. interjectus using artificial diets fungal medium. Our findings revealed that time eggs, larvae, pupae averages...
Aging is characterized by the deterioration of a wide range functions in tissues and organs, Alzheimer's disease (AD) neurodegenerative cognitive impairment. Hypothyroidism occurs when there insufficient production thyroid hormones (THs) thyroid. The relationship between hypothyroidism aging as well AD controversial at present.
Bark beetles overcome the toxic terpenoids produced by pine trees both detoxifying and converting them into a pheromone system. Detoxification enzymes such as cytochrome P450s, glutathione S-transferases, carboxylesterases are involved in ability of Dendroctonus armandi to adapt its chemical environment. Ten genes from these three major classes detoxification were selected study how help D. respond host defenses. The expression profile enzyme was observed adult after feeding on different...
Heat Shock Proteins 70 (HSP70s) in insects act on a diverse range of substrates to assist with overcoming extreme high temperatures. MaltHSP70-2, member HSP70s, has been characterized involve the thermotolerance Monochamus alternatus vitro, while quantification and localization MaltHSP70-2 various tissues its functional analysis vivo remain unclear.In this study, temporal expression indicated long-last inductive effect maintained 48 hours after heat shock. showed global response exposure...
The oral delivery of protein therapeutics offers numerous advantages for patients but also presents significant challenges in terms development. Currently, there is limited knowledge available regarding the stability and shelf life orally delivered therapeutics. In this study, a comprehensive assessment an solid dosage variable domain heavy-chain antibody (VHH antibody) drug product was conducted. Four related quality attributes that undergo change as result thermal humidity stress were...
The demand for animal products is increasing in developing countries due to population growth. However, livestock production contributes significantly global warming, accounting 25%. Probiotics can help improve efficiency by enhancing gut microbes and fat metabolism. They modify rumen populations, enhance fermentation, reduce methane emissions feed digestion. In this study, the goal was determine most effective method of reducing sheep vitro adding different concentrations Saccharomyces...
11β-hydroxylase deficiency (11β-OHD), caused by homozygosity or compound heterozygosity CYP11B1 variants, is the second most common cause of congenital adrenal hyperplasia (CAH). Due to high degree sequence identity between and CYP11B2, chimeric genes, complex structural variants (SVs), conventional approach gene testing for 11β-OHD facing challenges. The study aimed clarify underlying genetic causes two siblings a Chinese family with 11β-OHD.
Monochamus alternatus, the dominant vector of Bursaphelenchus xylophilus (Aphelenchida: Aphelenchoididae), has caused immense damage to forest resources. In China, this was native southern regions but spread northward recently. To adapt more challenging environments in northern winter, M. alternatus evolved an intricate strategy for overwintering, which remains largely unknown. Herein, we compared transcriptome data overwintering and non-overwintering larvae investigate molecular mechanisms...
Abstract A substantial increase in the occurrence of extremely high‐ or low‐temperature events caused by global climate change has imposed pressure on survival and reproduction invertebrates. Hyphantria cunea ( H. ; Lepidoptera: Arctiidae) is a worldwide defoliator become major forestry agricultural pest during past three decades China. The thermal cold tolerance directly affected population geographical distribution , which remains poorly understood. Here, we examined larvae discovered that...
Abstract Purpose 11β-hydroxylase deficiency (11β-OHD), caused by homozygosity or compound heterozygosity CYP11B1 mutations, is the second most common cause of congenital adrenal hyperplasia (CAH). Due to high degree sequence identity between and CYP11B2, chimeric genes, complex structural variants (SVs), conventional approach gene testing for 11β-OHD facing challenges. The study aimed clarify underlying genetic causes two siblings a Chinese family with 11β-OHD. Methods Peripheral blood...
Native to Asia, Euwallacea interjectus (Blandford) (Coleoptera: Curculionidae: Scolytinae) is a destructive and invasive pest of live trees, now it has been found in the United States Argentina. In recent years, this appeared high densities poplar monocultures from Eastern China (Jiangsu Shanghai) Argentina caused significant mortality. However, origin pests related tree damage Fusarium mutualists some zones remained unclear. Here, we provided broader phylogeographic analysis E. based on...
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