A5101645061- Bone Metabolism and Diseases
- Medicinal Plant Pharmacodynamics Research
- Ginseng Biological Effects and Applications
- Schizophrenia research and treatment
- Alzheimer's disease research and treatments
- Pharmacological Effects of Natural Compounds
- Diet and metabolism studies
- Diversity and Impact of Dance
- Tryptophan and brain disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Nuclear Receptors and Signaling
- Science Education and Pedagogy
- Caveolin-1 and cellular processes
- Ziziphus Jujuba Studies and Applications
- Genomic variations and chromosomal abnormalities
- Magnetic Field Sensors Techniques
- Genetics and Neurodevelopmental Disorders
- Child and Adolescent Psychosocial and Emotional Development
- Lipid metabolism and disorders
- Genomics and Rare Diseases
- Martial Arts: Techniques, Psychology, and Education
- Ultrasound and Hyperthermia Applications
- Genetic Associations and Epidemiology
- Personality Disorders and Psychopathology
- Psychosocial Factors Impacting Youth
Sun Yat-sen University
2009-2024
South China University of Technology
2024
Sun Yat-sen University Cancer Center
2024
National Engineering Research Center of Electromagnetic Radiation Control Materials
2024
University of Electronic Science and Technology of China
2024
Third Affiliated Hospital of Sun Yat-sen University
2009-2023
Guangdong Laboratory Animals Monitoring Institute
2016-2018
Novartis (Canada)
2018
Montreal Neurological Institute and Hospital
2018
Minzu University of China
2009-2017
Depression is a common mental disorder and leading cause of disability. At its most severe, it can lead to suicide. Recently, there has been growing interest in the application natural herbs for prevention treatment depression. In this report, we found that ginsenoside active component Rg3 an apparent antidepressant effect. N-methyl-d-aspartic acid (NMDA)-treated HT22 murine hippocampal neuronal cells, recovered proliferation inhibited apoptosis by altering cell cycle. More interestingly,...
Parkinson's disease (PD) is a degenerative disorder of the central nervous system mainly affecting motor system. Presently, there no effective and safe drug to treat patients with PD. Ginkgo biloba extract (GBE), obtained from leaves tree, complex mixture ingredients primarily containing two active components: flavonoids terpenoids. In this study, we investigated effects GBE on A53T α-synuclein transgenic mice, PD model that has better simulated progression than other models such as...
Abstract Objectives Total saponins from the leaves of Panax notoginseng (SLPN) could inhibit development depression, but underlying mechanisms remains unclear. This study aimed to address roles circular RNAs in depression inhibition by SLPN. Methods The mouse chronic unpredictable mild stress (CUMS) model was established, which were confirmed weight, forced swimming test (FST) and tail suspension (TST). Effects SLPN on evaluated CUMS through these same assays. Circular RNA profiles ventral...
Abstract Objective This study investigated the factors associated with high susceptibility of perimenopausal women to depression. Methods A total 66 participated in this study. The Zung self‐rating depression scale (SDS) was used evaluate intensity depressive symptoms. modified Kupperman index (KI) assess common Psychosocial were assessed via Eysenck Personality Questionnaire, attitudes toward menopause checklist, and metacognition questionnaire (MCQ). Levels serum estradiol, testosterone,...
Abstract Objectives To analyze psychological states and needs of patients after allogeneic hematopoietic stem cell transplantation (allo‐HSCT). Methods Questionnaires were sent to 101 allo‐HSCT survivors 96 questionnaires returned. The questionnaire covered several categories: (1) demographics general information, (2) physical conditions, (3) psychologic status sleep quality, (4) survivor's comments on transplantation, (5) demands needs, (6) preferred forms channels information. Results...
Although many studies have reported that glucose and lipid metabolism disorders are a significant side effect associated with the use of antipsychotic drugs, characteristics in patients schizophrenia who taking drugs remain poorly understood, possible effects discontinuation may on unclear.The sample consisted 131 Chinese schizophrenia, including 70 first-episode, drug-naïve patients; 33 had received continuous drug treatment for ≥1 year prior to beginning study; 28 discontinued ≥3 months...
This study aims to investigate the effects of low-dose olanzapine on preventing occurrence and controlling severity nausea vomiting related duloxetine in treating major depressive disorder.Two hundred sixty-eight subjects with disorder were divided into control trial groups. The group had 165 was treated only, whereas 103 received combined olanzapine. After treatment for 2 weeks, both groups evaluated adverse digestive tract using Treatment Emergent Symptom Scale.The group, scored at 13,...
The Chinese government has implemented centralised science curriculum standards to change teaching from a didactic inquiry-based approach support all students in acquiring literacy. Framed through theoretical perspectives of instruction and cultural pedagogy, this study examined the influence impact these reforms on performance 8th grade Inner-Mongolia Autonomous Regions using instruments developed by TIMSS 2007. It revealed that mixed, lecture-based, more practice-based approaches were...
One of the main challenges associated with development therapeutic and diagnostic strategies for patients colorectal cancer (CRC) is establishment minimally invasive efficient biomarkers. Pertinent genes in CRC have been identified through their functions systematic mutagenesis screens.
Abstract Orbitronics is an emerging domain within spintronics, and it characterized by a rapid development of methods for utilizing orbital current. Metals with strong spin‐orbit coupling have been effectively used to convert current into torque. This study introduces metallic [W/Ti] 3 superlattice that uses significantly enhance the magnetization switching efficiency. The enhancement in torque efficiency demonstrated via spin‐torque ferromagnetic resonance along extraction damping‐like ( ξ...
Platelet transfusion therapy has made a great breakthrough in clinical practice, and the differentiation of human embryonic stem cells (hESCs) to produce functional platelets become new potential approach, however, efficient generation still faces challenges. Here, we presented novel approach highly efficiently generate mature megakaryocytes (MKs) from hESCs. In hypoxic conditions, successfully replicated maturation process MKs controlled vitro environment by introducing an optimal...
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Objective To explore the association of methyl-CpG-binding protein2(MeCP2) polymorphisms with female schizophrenia in Chinese Han population. Methods By using technology based on micro-array Chip, gene polymorphism analysis 4 locus located MeCP2 was performed 126 patients fulfilled DSM-Ⅳ-TR criteria for and 144 healthy controls.Chi square test used to compare inter-group differences genotypic allelic distribution. Haplotype case-control linkage disequilibrium conducted SNP stats...
Objective To investigate the effect ofbuflomedil hydrochlorde on regional cerebral blood flow in different subtypes of schizophrenia.Methods Two hundred and eighty-six patient met diagnostic criteria CCMD-3 for schizophrenia,admitted to our hospital from February 2007 2009,were chosen study; patients type Ⅰ (n=86),type Ⅱ (n=63) Ⅲ (n=137)were randomly divided into treatment group (n=46),placebo (n=40),treatment (n=34),placebo (n=29),treatment Ⅲ(n=72) placebo (n=65).Patients groups were...