A5083890644- Epilepsy research and treatment
- Cerebrospinal fluid and hydrocephalus
- Fetal and Pediatric Neurological Disorders
- Spinal Dysraphism and Malformations
- Health and Medical Research Impacts
- Anatomy and Medical Technology
- Surgical Simulation and Training
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
- Advanced Neuroimaging Techniques and Applications
- History of Medical Practice
- Neurosurgical Procedures and Complications
- Meningioma and schwannoma management
- Pharmacological Effects and Toxicity Studies
- Mobile Health and mHealth Applications
- Trigeminal Neuralgia and Treatments
- Glioma Diagnosis and Treatment
- Diversity and Career in Medicine
- Neonatal and fetal brain pathology
- Global Health and Surgery
- EEG and Brain-Computer Interfaces
- Bacterial Infections and Vaccines
- Obsessive-Compulsive Spectrum Disorders
- Vestibular and auditory disorders
- Healthcare Systems and Technology
University of Alberta
2015-2025
Durham VA Medical Center
2023
British Columbia Children's Hospital
2023
Montreal Neurological Institute and Hospital
2018
Novartis (Canada)
2018
University of North Carolina Health Care
1993
Ventricular shunt infections lead to significant morbidity and mortality. This study aimed identify risk factors for 30-day postoperative infection outcomes of ventricular shunts pediatric hydrocephalus. was a retrospective cohort using the National Surgical Quality Improvement Program (NSQIP) Pediatric database years 2016-2021. Patients were included in this if they under 18 age underwent surgery. The primary outcome infection. A multivariable logistic regression analysis performed fourteen...
This study aims to refine computer-assisted planning (CAP) of SEEG implantations by adding spatial constraints from prior trajectories ("Priors") improve safety and reduce manual adjustments, without increasing time. Retrospective validation based on 159 previously implanted (11 cases) planned the clinical standard CAP constrained with priors ("CAP + Priors"). Constraints included 31 target 51 entry zones, created 98 consecutive patients (763 trajectories). Each was two fellows, once Priors,...
OBJECTIVE The aim of this study was to investigate long-term seizure outcome, rate reoperation, and postoperative neuropsychological performance following selective amygdalohippocampectomy (SelAH) or anterior temporal lobectomy (ATL) in pediatric patients with medically refractory lobe epilepsy (TLE). METHODS authors performed a retrospective review cases TLE treated initially either SelAH ATL. Standardized pre- evaluation included charting, surface video-electroencephalography, 1.5-T MRI,...
Background Many medically-refractory trigeminal neuralgia patients are non-responders to surgical treatment. Few studies have explored how nerve characteristics relate outcome, and none investigated the relationship between subcortical brain structure treatment outcomes. Methods We retrospectively studied undergoing with microvascular decompression. Preoperative magnetic resonance imaging was used for manual tracing of nerves automated segmentation hippocampus, amygdala, thalamus. Nerve...
OBJECTIVE External ventricular drainage (EVD) catheters are associated with complications such as EVD catheter infection (ECI), intracranial hemorrhage (ICH), and suboptimal placement. The aim of this study was to investigate the rates their risk factor profiles in order optimize safety accuracy insertion. METHODS A total 348 patients urgently placed were included a part prospective multicenter observational cohort. Strict definitions applied for each complication category. RESULTS...
Reperfusion with intravenous tissue plasminogen activator (tPA) has been the goal of therapy for acute ischemic stroke; however, tPA is contraindicated in many patients, low recanalization rates major occlusions, and carries a substantial risk symptomatic intracerebral hemorrhage. In present study, we hypothesized that partial intra-aortic occlusion abdominal aorta would increase salvage penumbra reduce infarct volume after focal embolic stroke rats. We examined effects aortic on volume,...
OBJECTIVE Knowledge-based tools used to standardize perioperative care, such as the shunt infection prevention protocol of Hydrocephalus Clinical Research Network (HCRN), have demonstrated their ability reduce surgeon-based and center-based variations in outcomes improve patient care. The mere presence high-quality evidence, however, does not necessarily translate into improved owing implementation gap. To advance understanding how knowledge-based are being utilized routine clinical care...
Abstract Background: Neurosurgical residents face a unique combination of challenges, including long duty hours, technically challenging cases, and uncertain employment prospects. We sought to assess the demographics, interests, career goals, self-rated happiness, overall well-being Canadian neurosurgery residents. Methods: A cross-sectional survey was developed sent through Neurosurgery Research Collaborative every resident enrolled in program as April 1, 2016. Results: analyzed 76...
This study was undertaken to evaluate the impact of postoperative MRI artifact on assessment ongoing spinal cord or nerve root compression after anterior cervical discectomy and fusion (ACDF) using a trabecular tantalum cage bone autograft allograft.The authors conducted retrospective review studies patients treated surgically for disc degenerative disease instability secondary trauma. Standard ACDF with either interbody graft had been performed. Postoperative MR images were shown twice in...
The avian nucleus of the basal optic root (nBOR) is a visual structure involved in optokinetic response. nBOR consists several morphologically distinct cell types, and present study, we sought to determine if these different types had differential projections. Using retrograde tracers, examined morphology distribution neurons projecting vestibulocerebellum (VbC), inferior olive (IO), dorsal thalamus, pretectal lentiformis mesencephali (LM), contralateral nBOR, oculomotor complex (OMC) group...
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Abstract Background Currently, the literature lacks reliable data regarding operative case volumes at Canadian neurosurgery residency programs. Our objective was to provide a snapshot of landscape in neurosurgical training using trainee-led Neurosurgery Research Collaborative. Methods: Anonymized administrative were gathered from each program January 1, 2014, December 31, 2014. Procedures broadly classified into cranial, spine, peripheral nerve, and miscellaneous procedures. A number...
Diffusion tensor imaging (DTI) tractography is commonly used in neurosurgical practice but largely limited to the preoperative setting. This due primarily image degradation caused by susceptibility artifact when conventional single-shot (SS) echo-planar (EPI) DTI (SS-DTI) acquired for open cranial, surgical position intraoperative (iDTI). Readout-segmented (RS) EPI (RS-DTI) has been reported reduce such not yet evaluated MRI (iMRI) environment. The authors performance of RS versus SS human brain iMRI
Mannitol is commonly used to treat elevated intracranial pressure (ICP). The authors analyzed mannitol dosing errors at peripheral hospitals prior or during transport tertiary care facilities for emergencies. They also investigated the appropriateness of use based on 2007 Brain Trauma Foundation guidelines severe traumatic brain injury.The conducted a retrospective review Shock Air Rescue Society (STARS) electronic patient database helicopter medical evacuations in Alberta, Canada, between...
The purpose of this study was to determine the publication rate and time following abstract presentation at a major neurosurgical meeting, namely 2005 annual meeting Congress Neurological Surgeons (CNS). We reviewed all 754 abstracts presented CNS status identify factors that are associated with publication. A standardized database search conducted status. Predictors were examined. Of presented, 383 (50.8%) published after 5.3 years. median 450 days (range-646 1953 days) 16% being prior...
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Background: The goals of evidence-based neurosurgery are to improve surgical outcomes, reduce complications, and provide an objective basis for altering practice. need higher quality studies, typically prospective multicentre, has been growing especially in light the evolving complexity neurosurgical interventions heterogeneity patient populations. In United Kingdom (UK), trainee-led research collaboratives have established tackle this problem. Therefore, we sought evaluate potential role a...
Background: The Canadian Neurosurgery Research Collaborative (CNRC) is a trainee-led multi-centre collaboration made up of representatives from 12 14 neurosurgical centres with residency programs. To demonstrate the potential this collaborative network, we gathered administrative operative data each centre in order to provide snapshot landscape neurosurgery. Methods: Residents training program provided adult for 2014 calendar year, including number surgeries subcategories cranial, spinal,...