A5084898347- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Streptococcal Infections and Treatments
- Dental Health and Care Utilization
- Dental Implant Techniques and Outcomes
- Dental Radiography and Imaging
- Oral and gingival health research
- Lipoproteins and Cardiovascular Health
- Cancer, Lipids, and Metabolism
- Protease and Inhibitor Mechanisms
- Infective Endocarditis Diagnosis and Management
- Systemic Lupus Erythematosus Research
- Metabolism, Diabetes, and Cancer
- Gut microbiota and health
- Neonatal and Maternal Infections
- Diabetes Treatment and Management
- Dental Research and COVID-19
- Hormonal and reproductive studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Sexual function and dysfunction studies
- Diabetes Management and Research
- Periodontal Regeneration and Treatments
- Neonatal Respiratory Health Research
- Delphi Technique in Research
- Inflammatory mediators and NSAID effects
Universidad de Granada
2015-2024
King's College London
2024
University of Palermo
2016-2023
The activation of inflammasomes is thought to induce the inflammatory process around dental implants. No information available on correlation between microbiota and in clinical samples from patients suffering peri-implantitis. For this cross-sectional study, 30 biofilm were obtained 19 undergoing surgical treatment for peri-implantitis because presence bleeding probing, probing depth higher than 6 mm, radiographic bone loss 3 mm. Then, soft tissue implant also collected. relative abundance...
The objective was to evaluate the effects of 6 months supplementation with Altilix®, containing chlorogenic acid and its derivatives, luteolin on cardiovascular risk hepatic markers in subjects metabolic syndrome (MetS). A randomized, double-blind, placebo-controlled study performed 100 MetS a follow-up period months; 50 were randomized Altilix® (26 men 24 women, mean age 63 ± 8 years) other placebo (28 22 11 years). Anthropometric, cardiometabolic, parameters assessed at baseline end...
Pre-obesity is a condition that predisposes to the risk of developing obesity, cardiovascular diseases (CVD), and diabetes. Our previous study demonstrated Cynara cardunculus (L.) based nutraceutical named Altilix® (Bionap, Italy), containing chlorogenic acid luteolin extracts, was able improve several hepatic cardio-metabolic parameters. Given this background, we conducted post-hoc analysis in order analyze supplement’s effects subgroup pre-obesity subjects on anthropometry (weight waist...
Liraglutide has shown favourable effects on several cardiometabolic risk factors, beyond glucose control. MicroRNAs (miRNAs) regulate gene expression, resulting in post-transcriptional modifications of cell response and function. Specific miRNAs, including miRNA-27b, miRNA-130a, miRNA-210, play a role disease. We aimed to determine the effect liraglutide serum levels miRNA-130a miRNA-210. Twenty-five subjects with type-2 diabetes mellitus (T2DM), naïve incretin-based therapy, were treated...
Cardiovascular disease has been associated with 40% of deaths in high-income countries and 28% lower-income countries. The relationship between periodontitis acute myocardial infarction is well documented, but it not established whether the extent severity influence infarct size. This cross-sectional analytic study was designed to investigate association chronic size as indicated by serum cardiac troponin I myoglobin levels. Sociodemographic, periodontal, cardiologic, hematologic variables...
The glucagon-like peptide-1 agonist (GLP1-RA) liraglutide is currently approved for the treatment of both obesity and type 2 diabetes (T2DM). We investigated whether effect this agent on cardiometabolic parameters in subjects with T2DM varied relation to concomitant presence obesity. One hundred thirty-five (78 men 57 women; age: 62 ± 10 years) naïve incretin-based therapies were treated low-dose (1.2 mg/day) as an add-on metformin 18 months. Patients divided into two subgroups based their...
Background and Objective Neutrophil extracellular traps (NETs) are a recently discovered antimicrobial mechanism used by neutrophils that have been proposed as an intervention in the pathogenesis of periodontitis. The objective our study was to characterize expression NETs gingival tissues with periodontitis controls compare these tissue samples patients gingivitis Material Methods An observational cross‐sectional conducted on periodontitis, gingivitis, needed tooth extraction. Gingival...
Background: The purpose of this case–control study is to investigate the association between stress and periodontitis by determining biomarkers in saliva urine determine whether oral hygiene, gingival inflammation, tooth loss are correlated with patients periodontitis. Methods: A total 77 (41 cases [with periodontitis] 36 controls) participated study. Periodontal examination findings included probing depth, clinical attachment loss, bleeding on (BOP), plaque index (PI), loss. Secretory...
Background: The objective of this study is to determine whether simvastatin consumption and hyperlipidemia are associated with a worse periodontal condition specific bone activity biomarkers. Methods: This cross‐sectional analytic includes 73 patients divided into three groups: 1) simvastatin‐treated (n = 29); 2) treated by diet alone 28); 3) normolipidemic (controls, n 16). clinical variables all participants were gathered, blood sample was drawn from each the lipid profile (total...
Short- or long-term implant survival and success are related to peri-implant marginal bone loss (MBL), among other key factors. The purpose of this study was analyze the role clinical implant-related variables in MBL over a follow-up.A retrospective 558 implants 172 patients conducted, analyzing relationship between clinical, implant-related, prosthetic design-related variables. measured on digital radiographs with specific software, using threads as reference.Linear mixed analysis revealed...
To relate five periodontopathogenic bacteria, including the red complex, to severity, extent, and inflammation of periodontal lesion in Caucasian patients with generalized aggressive chronic periodontitis explore whether tobacco use is associated a specific bacterial profile.A cross-sectional analytic study was conducted periodontitis. Data were gathered on socio-demographic variables, RH-PCR used determine subgingival profile. Linear logistic regression analyses performed.The included 60...
The aim of our study was to evaluate the effects a hyaluronic acid (HA) gel at 45 days on microbiome implants with peri-implantitis least 1 year loading.A randomized controlled trial conducted in patients. Swabs containing samples were collected both baseline and after treatment. 16S rRNA sequencing techniques used investigate effect HA subgingival microbiome.One hundred eight 54 patients analyzed follow-up days. Three strata different microbial composition obtained baseline, representing...
To determine the incidence of tooth loss in patients with generalized aggressive periodontitis (GAgP) during supportive periodontal therapy (SPT), identify risk factors, and quantify alveolar crest height changes on periapical X-ray follow-up.This retrospective study included 25 GAgP 656 teeth after treatment (baseline). Data were gathered sociodemographic, periodontal, radiological variables at baseline end follow-up. Linear regression models used to assess association factors...
Abstract To determine the effects on gingival bleeding, dental biofilm, and salivary flow pH in patients with gingivitis of using toothpaste extra-virgin olive oil (EVOO), xylitol, betaine comparison to a placebo or commercial toothpaste. This controlled, double blinded, multicenter randomized clinical trial included randomly assigned one three groups: test group (EVOO, toothpaste), control 1 (placebo 2 (commercial toothpaste). Percentage supragingival biofilm bleeding were evaluated at...
Abstract Aim To assess periodontal stability and the association between tooth‐ patient‐related factors tooth loss during supportive care (SPC). Materials Methods A prospective observational study was carried out on previously treated periodontitis patients followed up for 5 years in SPC. The risk profile (low, moderate, high) of each patient based assessment (PRA) scoring at baseline evaluated, rates were analysed. Results Two hundred included study, 143 had 5‐year follow‐up data available...
Abstract Aim To determine the association between chronic periodontitis and erectile dysfunction adjusting for biochemical markers other comorbidities. Methods A case–control study was conducted on 158 male patients; 80 cases with according to International Index of Erectile Function 78 controls. Sociodemographic data were gathered, a periodontal examination performed. Testosterone, lipid profile, C‐reactive protein glycaemic parameters assessed. All variables compared groups, multivariate...