Thomas Looi

ORCID: 0000-0001-6453-2928
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About
Contact & Profiles
Research Areas
  • Soft Robotics and Applications
  • Surgical Simulation and Training
  • Cerebrospinal fluid and hydrocephalus
  • Anatomy and Medical Technology
  • Augmented Reality Applications
  • Micro and Nano Robotics
  • Ultrasound and Hyperthermia Applications
  • Cleft Lip and Palate Research
  • Advanced MRI Techniques and Applications
  • Craniofacial Disorders and Treatments
  • Piezoelectric Actuators and Control
  • Neonatal and fetal brain pathology
  • Robotic Mechanisms and Dynamics
  • Modular Robots and Swarm Intelligence
  • Spinal Dysraphism and Malformations
  • Ultrasound Imaging and Elastography
  • Medical Image Segmentation Techniques
  • Simulation-Based Education in Healthcare
  • Head and Neck Surgical Oncology
  • Fetal and Pediatric Neurological Disorders
  • Facial Trauma and Fracture Management
  • Minimally Invasive Surgical Techniques
  • Tracheal and airway disorders
  • Medical Imaging and Analysis
  • Dental Implant Techniques and Outcomes

Hospital for Sick Children
2016-2025

University of Toronto
2015-2024

SickKids Foundation
2015-2024

Canada Research Chairs
2024

Great Ormond Street Hospital
2024

University College London
2024

Guided Therapeutics (United States)
2016-2022

Yahoo (United Kingdom)
2018

Cleft palate repair is a challenging procedure to learn because of the delicate tissue handling required and small confines infant oral cavity. As result, cleft simulators have previously been described augment training. Although valuable, they lack fidelity for this complex procedure.A high-fidelity simulator was evaluated by staff fellows in pediatric plastic surgery who provided feedback on its realism, anatomical accuracy, effectiveness as training tool. The implemented within workshop...

10.1097/prs.0000000000002923 article EN Plastic & Reconstructive Surgery 2016-12-29

Infants with craniosynostosis involving the metopic and coronal sutures require cranio-orbital reshaping to correct craniofacial dysmorphologic feature improve facial balance. Currently, surgical techniques create a balanced fronto-orbital region are based on surgeon's subjective approach artistic vision in creating normal shape forehead. To date, use of age-matched templates computer-assisted design/computer-assisted manufacturing optimizing outcomes intervention this area have not been...

10.1097/scs.0b013e31822e8045 article EN Journal of Craniofacial Surgery 2011-09-01

OBJECT Endoscopic third ventriculostomy (ETV) is an effective but technically demanding procedure with significant risk. Current simulators, including human cadavers, animal models, and virtual reality systems, are expensive, relatively inaccessible, can lack realistic sensory feedback. The purpose of this study was to construct a realistic, low-cost, reusable brain simulator for ETV evaluate its fidelity. METHODS A silicone replica mimicking normal mechanical properties 4-month-old child...

10.3171/2014.9.peds1447 article EN Journal of Neurosurgery Pediatrics 2014-10-31

This work presents a novel miniature contact-aided compliant joint mechanism that can be integrated into millimeter-sized manual or robotic surgical instruments. The design aims to address the trade-off between notched-tube joints' range of motion and stiffness, while also ensuring compact form factor. is constructed from nitinol tube with asymmetric cutouts actuated in bending by cable. innovative feature this incorporation contact aid topology, which acts both increase stiffness change...

10.1115/1.4038254 article EN Journal of Mechanisms and Robotics 2017-10-23

In this letter, a novel end-effector for surgical applications is presented that uses magnetic actuation in lieu of more traditional cable-driven tool with the goal providing high dexterity hard-to-reach locations by decoupling from rest system. The gripper and wrist device consists several magnets connected compliant Nitinol joints allow two rotational degrees freedom one gripping degree freedom. As an existing robot arm, could augment minimally invasive robots allowing distal sites narrow...

10.1109/lra.2019.2894504 article EN IEEE Robotics and Automation Letters 2019-01-21

A major advantage of surgical robots is that they can reduce the invasiveness a procedure by enabling clinician to manipulate tools as would in open surgery but through small incisions body. Neurosurgery has yet benefit from this advantage. Although clinical are available for least invasive neurosurgical procedures, such guiding electrode insertion, most brain surgeries, tumor resection, still performed manual procedures. To investigate whether robotics could surgeries while providing...

10.1126/scirobotics.adg6042 article EN Science Robotics 2023-09-13

Cleft palate repair is technically challenging: visualization reduced, delicate dissection required, and instrument reachability limited within the infant oral cavity using standard instruments. A 3 mm diameter pin-jointed wristed tool was developed that couples to a da Vinci Research Kit (dVRK) perform cleft surgery. simulation analysis performed determine number of collisions (tool-tool tool-cavity) for tip positions impact dVRK trocar height. Tool measured ratio collision-free total poses...

10.1109/tbme.2025.3534119 article EN IEEE Transactions on Biomedical Engineering 2025-01-01

Operating in the brain for deep-seated tumors or surgical targets epilepsy is technically demanding and normally requires a large craniotomy with its attendant risk morbidity. Neuroendoscopic surgery has potential to reduce morbidity by permitting access through small incision burr hole narrow corridor brain. However, current endoscopic neurosurgical tools are straight rigid lack dexterity, hindering their adoption neuroendoscopic procedures. We propose class of robotic that have...

10.1126/scirobotics.adk4249 article EN Science Robotics 2025-03-26

In this paper, a novel approach for automated suturing is introduced and experimental results are presented. Unlike other similar works, the proposed adopts single arm to implement task with standard laparoscopic needle holder curved suture needle. 3D information obtained from clinical (single camera) endoscope through an elliptical/circular pose measurement algorithm, which dynamically tracks surface markers. This drives robotic steering set of surgeon-defined entry/exit points on tissue...

10.1109/icra.2013.6630582 article EN 2013-05-01

Background: A surgical robot offers enhanced precision, visualization, and access the potential to improve outcomes in cleft palate surgery. The goal of this study was investigate feasibility using da Vinci for repair infants a simulator test bed. Methods: high-fidelity developed that allows performance robotic procedure. complete performed with Si 5-mm instruments Xi 8-mm instruments. advantages approach were assessed comparison standard For each system, arm repositioning, collisions,...

10.1097/prs.0000000000003010 article EN Plastic & Reconstructive Surgery 2017-02-01

Background: This study assessed technical performance in cleft palate repair using a newly developed assessment tool and high-fidelity simulator through longitudinal simulation training exercise. Methods: Three residents performed five one resident nine consecutive endoscopically recorded repairs simulator. Two fellows pediatric plastic surgery two expert surgeons also simulated repairs. The Cleft Palate Objective Structured Assessment of Technical Skill (CLOSATS) end-product scales were to...

10.1097/prs.0000000000004426 article EN Plastic & Reconstructive Surgery 2018-03-25

Remote-controlled minimally invasive neuroendoscopic robotic surgical tools can be miniaturized to a size of less than 2 mm while maintaining their dexterity and force required perform operations in brain without an open-skull surgery. However, these platforms lack haptic information received by the surgeons, leading loss control over tissue causing unexpected slippage trauma. This study presents design small highly sensitive material-based sensor being integrated tool shaft, known as...

10.1109/tie.2020.2984427 article EN IEEE Transactions on Industrial Electronics 2020-04-09

The da Vinci Surgical System is a commercially available surgical robotics platform used to perform more than 450,000 surgeries annually, primarily for gynecological and urological procedures [1]. This technology enhances the surgeon's dexterity through use of multiarm robot with wristed instruments that enter patient's body small incisions. However, size existing (5-8 mm in shaft diameter) has prevented adoption system areas such as neurosurgery, head neck surgery, pediatrics [2], [3]....

10.1109/mra.2017.2680547 article EN IEEE Robotics & Automation Magazine 2017-05-12

Concentric-tube manipulators could experience a snapping-through motion that negatively impacts their smooth operation. This may limit adoption in the operating room, despite advantage of enabling dexterity within highly confined space. In this paper, we demonstrate through kinematics concentric-tube robots, how adverse effect torsion be reduced or potentially eliminated. As proof principle, experimentally and numerically by adopting tubular composite structures, such as multi-layer helical...

10.1109/iros.2014.6942833 article EN 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems 2014-09-01

We present a kinetostatic model for needle-sized notched tube continuum joint design, and examine the impact that design parameters have on both stiffness kinematics. The is fabricated by removing series of asymmetric notches from metal tube. By fixing cable to distal end tube, routing this tendon through tube's lumen, can be actuated in bending. This simple cutting pattern allows impressive performance compared other mechanisms similar size. However, selecting geometry using kinematics...

10.1109/iros.2016.7759371 article EN 2021 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) 2016-10-01

OBJECTIVE Endoscope-assisted repair of craniosynostosis is a safe and efficacious alternative to open techniques. However, this procedure challenging learn, there significant variation in both its execution outcomes. Surgical simulators may allow trainees learn practice prior operating on an actual patient. The purpose study was develop realistic, relatively inexpensive simulator for endoscope-assisted metopic sagittal evaluate the models’ fidelity teaching content. METHODS Two separate,...

10.3171/2018.2.peds18121 article EN Journal of Neurosurgery Pediatrics 2018-06-01

Robot-assisted minimally invasive surgical (MIS) techniques offer improved instrument precision and dexterity, reduced patient trauma risk, promise to lessen the skill gap among surgeons. These approaches are common in general surgery, urology, gynecology. However, MIS remain largely absent for applications within narrow, confined workspaces, such as neuroendoscopy. The limitation stems from a lack of small yet dexterous robotic tools. In this work, we present first instance robot with...

10.1109/tbme.2020.3007581 article EN IEEE Transactions on Biomedical Engineering 2020-07-08

Abstract Background The availability of open and versatile software tools is a key feature to facilitate pre-clinical research for magnetic resonance imaging (MRI) resonance-guided high-intensity focused ultrasound (MR-HIFU) expedite clinical translation diagnostic therapeutic medical applications. In the present study, two customizable that were developed at Thunder Bay Regional Research Institute are presented use with both MRI MR-HIFU. Both operate in MATLAB ®; environment. first tool...

10.1186/2050-5736-1-7 article EN cc-by Journal of Therapeutic Ultrasound 2013-06-04

Surgical simulators not only allow planning and training of complex procedures, but also offer the ability to generate structured data for algorithm development, which may be applied in image-guided computer assisted interventions. While there have been efforts on either developing platforms surgeons or generation engines, these two features, our knowledge, offered together. We present developments a cost-effective synergistic framework, named Asynchronous Multibody Framework Plus (AMBF+),...

10.1080/21681163.2021.1999331 article EN Computer Methods in Biomechanics and Biomedical Engineering Imaging & Visualization 2021-11-26
J. Brian Fowlkes Pejman Ghanouni Narendra T. Sanghvi Constantin Coussios Paul Lyon and 95 more Michael Gray Christophoros Mannaris Marie de Saint Victor Eleanor Stride Robin O. Cleveland Robert Carlisle Feng Wu Mark R. Middleton Fergus Gleeson Jean-Franҫois Aubry Kim Butts Pauly Chrit Moonen Jacob Vortman Pejman Ghanouni Shirley Sharabi Dianne Daniels David Last David Guez Yoav Levy Alexander Volovick Javier Grinfeld Itay Rachmilevich Talia Amar Zion Zibly Yael Mardor Sagi Harnof Michael Plaksin Yoni Weissler Shy Shoham Eitan Kimmel Omer Naor Nairouz Farah Shy Shoham Dong‐Guk Paeng Zhiyuan Xu John Snell Anders Quigg Matthew Eames Changzhu Jin Ashli Everstine Jason P. Sheehan Beatriz S. Lopes Neal F. Kassell Thomas Looi Vera A. Khokhlova Charles Mougenot Kullervo Hynynen James M. Drake Michael H. Slayton Richard C. Amodei Keegan B. Compton Ashley McNelly L. Daniel Latt Michael H. Slayton Richard C. Amodei Keegan B. Compton John Kearney David Melodelima Aurélien Dupré Yao Chen David Pérol Jérémy Vincenot Jean‐Yves Chapelon Michel Rivoire Wei Guo Guoxin Ren Guofeng Shen Michael Neidrauer Leonid Zubkov Michael S. Weingarten David J. Margolis Peter A. Lewin Nathan McDannold Jonathan Sutton Natalia Vykhodtseva Margaret S. Livingstone Thiele Kobus Yongzhi Zhang Natalia Vykhodtseva Nathan McDannold Michael L. Schwartz Yuexi Huang Nir Lipsman Jennifer Jain Martin Chapman Tejas Sankar Andrés M. Lozano Kullervo Hynynen Michael L. Schwartz Robert Yeung Yuexi Huang Nir Lipsman Jennifer Jain Martin Chapman Andrés M. Lozano

10.1186/s40349-016-0079-2 article EN Journal of Therapeutic Ultrasound 2017-03-17

Abstract This work presents the design of an articulate neuroendoscopic instrument (ANI), a handheld tool for use in minimally invasive neurosurgery. The consists handle and steerable tube-shaft with distal end-effector. aims to increase reach surgeons operating through narrow channels within center brain when approaching multiple targets from single incision point. 1.6- mm notch-tube compliant joint mechanism augmented contact-aids modeled after gear geometry. contact-aid geometry address...

10.1115/1.4045934 article EN Journal of Medical Devices 2020-01-11
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