A5047394789- Multiple Myeloma Research and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Protein Degradation and Inhibitors
- Analytical Methods in Pharmaceuticals
- Airway Management and Intubation Techniques
- Genital Health and Disease
- Parathyroid Disorders and Treatments
- Pharmacological Effects and Toxicity Studies
- Neuroendocrine Tumor Research Advances
- Respiratory Support and Mechanisms
- Myasthenia Gravis and Thymoma
- Peripheral Neuropathies and Disorders
- Cancer Treatment and Pharmacology
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis B Virus Studies
- Complement system in diseases
- HIV/AIDS drug development and treatment
- Peptidase Inhibition and Analysis
- COVID-19 and healthcare impacts
- HIV Research and Treatment
- Electrolyte and hormonal disorders
- Male Reproductive Health Studies
- Parasitic infections in humans and animals
- Legionella and Acanthamoeba research
- Vitamin D Research Studies
National and Kapodistrian University of Athens
2006-2024
Alexandra Hospital
2006-2024
Weatherford College
2020
University College Hospital
2016
University College London
2016
Clinical trials with carfilzomib have indicated a low but reproducible incidence of cardiovascular and renal toxicities. Among 60 consecutive myeloma patients treated carfilzomib-based regimens who were thoroughly evaluated for risk factors, 12% (95% confidence interval, 3.8%-20%) experienced reversible reduction left ventricular ejection fraction (LVEF) by ≥20%, an objective measure cardiac dysfunction. The LVEF was 5% at 3 months, 8% 6 10% 12 15 whereas the respective discontinuation rate...
High-flow oxygen through nasal cannula (HFNC) provides adequate oxygenation and can be an alternative to noninvasive ventilation (NIV) for patients with hypoxemic respiratory failure. The aim of the present study was assess efficacy HFNC versus NIV in hypercapnic Patients (n = 40) who were admitted Emergency Department Alexandra Hospital due failure (PaCO2 ≥ 45 mmHg) randomized assigned into two groups, i.e., intervention group (use HFNC, n 20) a control NIV, 20). During their...
Abstract Carfilzomib (CFZ) is a non-reversible proteasome inhibitor approved for the treatment of patients with relapsed and refractory myeloma (RRMM). Its use has been associated cardiovascular toxicity but although recently signal clinically significant renal complications also identified, it less extensively investigated. We analyzed data 114 consecutive RRMM who received CFZ-based regimens. Renal not related to MM progression were observed in 19 (17%) patients; thrombotic microangiopathy...
COVID-19 pandemic caused a major crisis, affecting and straining health care systems, including some very advanced ones. The may have also indirectly affected access to for patients with other conditions, not related COVID-19, even in countries overwhelmed by an outbreak.We analyzed compared visits the emergency room (ER) department during same calendar period of 2019 2020 (from March 1 31 each year) our hospital, medium size, tertiary center, located center Athens, which is referral...
Tenofovir disoproxil fumarate (TDF) is a nucleotide reverse transcriptase inhibitor that has been widely used for the treatment of patients with human immunodeficiency virus (HIV) and hepatitis B (HBV) infections. Despite excellent safety records this regimen, few cases acute renal failure Fanconi syndrome have reported among HIV exposed to TDF. However, in HBV monoinfection scenario, only five TDF-associated thus far, two them providing confirmatory kidney biopsy. Here, we describe case...
We report a unique case of an adverse interaction between the oxazolidinone antibiotic linezolid, tricyclic antidepressant amitriptyline and opioid analgesic fentanyl in 68-year-old woman with advanced ischemic peripheral arterial disease sepsis, under empirical treatment. also summarize current relevant literature as identified via PubMed, EMBASE, PsycINFO well reference sections selected articles.
Objective To investigate 25(OH)D3 levels and their relationship to survival in a cohort of acutely ill patients on admission an intensive care unit. Methods This study enrolled at unit group sex- age-matched healthy control subjects. The were measured using enzyme immunoassay. C-reactive protein procalcitonin also immunoassays. Results A total 50 subjects the study. mean ± SEM significantly lower compared with (11.74 0.88 ng/ml versus 24.66 1.60 ng/ml, respectively). not related survival. An...
<b>Introduction:</b> It is well known that Non Invasive Mechanical Ventilation (NIMV) with Bi-level Positive Airways Pressure (BiPAP) the gold standard for respiratory failure type II. <b>Objective:</b> The aim of our study to evaluate BiPAP versus high flow nasal cannula warm humidified air oxygen therapy. <b>Methods:</b> A total twenty patients were assigned two types therapy - ten each group. All admitted in High Dependency Unit Alexandra Hospital because acute II (pCO2≥46mmHg). mean age...
We report the case of a 63-year-old patient with myasthenia gravis (MG) due to acetylcholine receptor antibodies (AChR) who underwent colectomy colon adenoma and developed myasthenic crisis anastomosis leakage after surgery. The two plasma exchanges, 4 6 days preoperatively, received intravenous prednisolone immunoglobulin infusion crisis, which included primarily bulbar symptoms. on 10th postoperative day bowel obstruction symptoms required surgical repair ileostomy. Bowel occurred in AChR...