A5090954667- Neuroscience and Neuropharmacology Research
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Immune cells in cancer
- Stress Responses and Cortisol
- Hormonal Regulation and Hypertension
- Biochemical Acid Research Studies
- Electrolyte and hormonal disorders
- Immune Response and Inflammation
- Peroxisome Proliferator-Activated Receptors
- Drug-Induced Hepatotoxicity and Protection
- Tryptophan and brain disorders
- Phagocytosis and Immune Regulation
- Acute Kidney Injury Research
- Circadian rhythm and melatonin
- GABA and Rice Research
Benha University
2021-2024
Hashemite University
2021-2024
Cairo University
2022
Acute kidney injury (AKI) is a prevalent medical condition accompanied by mutual affection of other organs, including the liver resulting in complicated multiorgan malfunction. Macrophages play vital role during tissue and healing; they are categorized into "classically activated macrophages" (M1) "alternatively (M2). The present study investigated compared conventional fluid therapy vs Dipeptidyl peptidase 4 inhibitor (DPP-4i) vildagliptin on induced AKI evaluated possible molecular...
ABSTRACTEnvironmental factors, such as sleep restriction, contribute to polycystic ovary syndrome (PCOS) by causing hyperinsulinemia, hyperandrogenism, insulin resistance, and oligo- or anovulation. This study aimed evaluate the effects of circadian rhythm disruption on reproductive metabolic functions investigate potential therapeutic benefits MitoQ10 hot tub therapy (HTT). Sixty female rats were divided into six groups: control, MitoQ10, HTT, three groups with PCOS induced continuous light...
Acute kidney injury (AKI) is commonly a result of renal ischemia reperfusion (IRI), which produces clinical complications characterized by the rapid deterioration function, leading to chronic disease and increases risk morbidity mortality. Currently, only supportive treatment available. AKI, accompanied immune activation inflammation, caused proximal tubular injury. The present study investigated role epithelial cells as drivers inflammation in IRI their potential function antigen‑presenting...
(2021). Bone marrow mononuclear cells boosts anti-cytogentical aberration effect of N-acetylcysteine and α-lipoic acid in rat's liver bone marrow: implication oxidative inflammatory pathways. Toxicology Mechanisms Methods: Vol. 31, No. 6, pp. 437-449.
Metabolic Syndrome (MetS) is considered a common disorder, especially with sedentary lifestyle and unhealthy food consumption. Cognitive impairment one of the MetS consequences that worsens quality life patients. The study aimed to assess therapeutic effect neurosteroid Allopregnalonone on spatial memory and, therefore, expression two synaptic plasticity markers in hippocampus. Thirty-two male rats were divided into four groups: control groups, MetS, + Allopregnalone. Spatial has been...
Hormonal disturbances, multiple ovarian cysts, and oligo-anovulation are the key features of polycystic syndrome (PCOS).Consistently, without a directly hormone-regulated animal model, we developed three phenotypes PCOS in rats to simulate reproductive-metabolic disturbances human PCOS.Twenty-four female Sprague-Dawley underwent vaginal smears for two sequential cycles exclude any PCOS-like rats.Rats were divided into following groups: healthy control, induced by high-fat, high-sugar (HFHS)...