- Mechanical Circulatory Support Devices
- Cardiac Ischemia and Reperfusion
- Transplantation: Methods and Outcomes
- RNA Interference and Gene Delivery
- Hemostasis and retained surgical items
- Virus-based gene therapy research
- Cardiac Arrest and Resuscitation
- Renal Transplantation Outcomes and Treatments
- Surgical Sutures and Adhesives
- Hemophilia Treatment and Research
- Peptidase Inhibition and Analysis
- Viral Infections and Immunology Research
- Heart Rate Variability and Autonomic Control
- Aortic Disease and Treatment Approaches
- Diabetes and associated disorders
- Blood groups and transfusion
- Antifungal resistance and susceptibility
- Cardiovascular and exercise physiology
- Cardiac and Coronary Surgery Techniques
- Antiplatelet Therapy and Cardiovascular Diseases
- Hepatitis C virus research
- Cardiac Structural Anomalies and Repair
- Viral gastroenteritis research and epidemiology
- Fuel Cells and Related Materials
- Protein Tyrosine Phosphatases
University of California, Los Angeles
1995-2024
Atrium Medical (Australia)
2012-2023
UCLA Health
2011-2019
VA West Los Angeles Medical Center
2013
Thoracic Surgery Foundation
2012
University of Iowa Hospitals and Clinics
2012
RELX Group (Netherlands)
2012
Islamic Azad University Bandar Abbas
2011
UCLA Medical Center
1995-2001
University of California, San Francisco
1990
Background. Reperfusion injury (RI) is a major cause of mortality and morbidity among lung transplant recipients. We sought to determine if prophylactic administration inhaled nitric oxide (NO) recipients at reperfusion would prevent RI. also hypothesized that NO proves ineffective in preventing RI then it may improve pulmonary hemodynamics gas exchange the subset patients who develop Methods. After informed consent, 28 consecutive, adult received 20 ppm reperfusion. was withdrawn for 15 min...
Background A modification of the Fontan procedure with unidirectional cavopulmonary connection is described in which superior vena cava (SVC) connected to left pulmonary artery (PA) and inferior (IVC) right PA via a lateral tunnel snare-controlled, adjustable atrial septal defect (ASD). This allows matching SVC IVC flows lung appropriate size. The obligatory Glenn shunt provides an adequate arterial oxygen saturation, elevation pressure well tolerated. ASD selective decompression that...
Cardiomyopathy secondary to toxic shock syndrome (TSS) is an uncommon but potentially life-threatening problem. We report the case of a 51-year-old male who presented with profound cardiogenic and multiorgan failure that could not be managed by conventional therapy intravenous fluids, vasopressors inotropes. Venoarterial extracorporeal membrane oxygenation (VA ECMO) was instituted as bridge recovery. After administration antibiotics immunoglobulin, patient’s condition improved he...
Aims of the study The safety and efficacy a hemostatic powder (HP) versus control agent, absorbable gelatin sponge thrombin (G + T), were assessed, using validated, quantitative bleeding severity scale. Methods Subjects randomized to receive HP (256 subjects) or G T (132 for treatment minimal, mild, moderate at 20 investigational sites. primary endpoint was non-inferiority relative success achieving hemostasis within 6 minutes. Secondary endpoints in rank order included: superiority mean...
Aim This trial compared the hemostatic performance of a novel combination powder (CP) to control matrix (HM) in cardiothoracic operations. Methods Patients meeting eligibility criteria were enrolled after providing informed consent. Subjects randomized intraoperatively receive CP (HEMOBLAST Bellows; Biom'up, France) or HM (FLOSEAL Hemostatic Matrix; Baxter Healthcare Corporation, Hayward, CA). Bleeding was assessed using clinically validated, quantitative bleeding severity scale. The primary...
Abstract Commercially available cardioplegia delivery systems now allow for antegrade (aortic root, coronary ostia, saphenous vein graft) perfusion to occur either sequentially or simultaneous with retrograde (coronary sinus) perfusion. This study was designed compare the total flow and local distribution of sequential versus antegrade/retrograde delivery. Methods: Explanted human hearts diagnosed idiopathic cardiomyopathy underwent a cold cardioplegic arrest bicaval cardiectomy....
Purpose: To clarify patterns of anti-HLA antibody expression (sensitization) occurring in patients bridged to transplantation (BTT) with ventricular assist devices (VADs). Methods: The study is a retrospective review 68 undergoing BTT either Heartmate II (HMII) axial flow LVAD or paracorporal BIVAD from January 2007 July 2010 at UCLA Medical Center. Results: Five 15 (33.3%) HMII pts became sensitized during treatment compared 29 53 (54.7%) patients, p=0.24. Table 1 shows common etiologies...