A5061767175- Systemic Lupus Erythematosus Research
- Musculoskeletal synovial abnormalities and treatments
- Rheumatoid Arthritis Research and Therapies
- Bone and Joint Diseases
- Viral-associated cancers and disorders
- Lymphoma Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Inflammatory Myopathies and Dermatomyositis
- Dialysis and Renal Disease Management
- Sarcoidosis and Beryllium Toxicity Research
- Atherosclerosis and Cardiovascular Diseases
- 3D Printing in Biomedical Research
- IL-33, ST2, and ILC Pathways
- Complement system in diseases
- Autoimmune and Inflammatory Disorders
- Pneumonia and Respiratory Infections
- Aerospace and Aviation Technology
- Cardiovascular Disease and Adiposity
- Bacterial Infections and Vaccines
- Eosinophilic Disorders and Syndromes
- Chronic Kidney Disease and Diabetes
- Neurological Complications and Syndromes
- Air Traffic Management and Optimization
- Spectroscopy and Quantum Chemical Studies
- Robotic Path Planning Algorithms
Seirei Hamamatsu General Hospital
2025
Kitasato University
2019-2023
Tokyo University of Pharmacy and Life Sciences
2023
Shibaura Institute of Technology
2019
Shinonoi General Hospital
2017
AbbVie (United States)
2013
AbbVie (Japan)
2013
Objectives Demyelinating syndromes that result in brainstem and/or spinal cord lesions similar to those observed neuromyelitis optica spectrum disorder (NMOSD) as neuropsychiatric systemic lupus erythematosus (NPSLE) occasionally develop patients with SLE. Cerebrospinal fluid (CSF) interleukin (IL)-6 is a known biomarker for NMOSD; however, its application SLE unknown. Additionally, the breakdown of blood–brain barrier (BBB) integrity by autoantibodies another mechanism it not elucidated...
A 40-year-old man with systemic lupus erythematosus taking consecutive oral corticosteroids developed a high-grade fever and disorder of consciousness following acute rhinitis. Haemophilus influenzae type f (Hif) was found isolated from the blood cerebrospinal fluid by culture, leading to diagnosis meningitis. The prevalence H. b (Hib) infections has decreased due routine immunization. As result, invasive non-Hib, including Hif infection, is increasing as common infection in children adults....
A 39-year-old woman admitted with multiple joint pain, hand rashes, and shortness of breath was diagnosed anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM) interstitial pneumonia (IP). Because progressive dyspnoea hypoxaemia, her IP considered rapidly lung disease. Initially, prednisolone 60 mg/day, cyclosporine (CyA), intravenous cyclophosphamide (IVCY) were initiated. few days following the initiation treatment, she experienced massive...
<h3>Background</h3> Rheumatoid arthritis (RA) significantly impairs work productivity and daily activities. <h3>Objectives</h3> To examine the effectiveness of adalimumab (ADA) with respect to RA-related activity impairment, as well associations changes in outcomes disease activity, Japanese patients different employment statuses. <h3>Methods</h3> Data were taken from first 24 weeks a 48-week, multicenter, prospective, single-cohort study self-reported impairment 475 RA receiving ADA....
<h3>Background</h3> Axial spondyloarthritis (AxSpA) can be triggered by infection and environmental factors, some cases involve trauma. Whiplash injury in a traffic accident may lead to exacerbation of symptoms AxSpA. <h3>Objectives</h3> The aims this study are survey the prevalence trauma before or after onset AxSpA examine prevalences neck other patients with history <h3>Methods</h3> completed questionnaire, clinical presentation, inflammatory markers (ESR, CRP), radiographs, MRI...
Recently, multicopter UAVs perform various tasks in a variety of areas including inside corrupt building and so on. In such situation, an air flow due to wall or ceiling may affect control the multicopters. This paper experimentally verifies influence UAV near ceiling. experiment, three environmental cases are considered, namely only UAV, both close UAV. The experimental results show that thrust increases moment is generated wall.
今回我々が経験した症例は約20年来の関節リウマチを基礎疾患に持ち，メトトレキサート（Methotrexate：MTX）内服中，有痛性の肛囲潰瘍の精査のため当科紹介となった67歳女性の症例である。
ABSTRACT Castleman’s disease (CD), especially multicentric CD (MCD) has been known to manifest a variety of clinical features such as fatigue, anaemia, fever, and hypergammaglobulinaemia. Here, we report 72-year-old female patient who had complicated severe synovitis, an initial manifestation the disease, lastly diagnosed MCD. Initially, she remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) syndrome because bilateral leg significant C-reactive protein matrix...
Anti-ribosomal P protein antibodies (anti-ribo P) have been reported as one of the specific autoantibodies in patients with systemic lupus erythematosus (SLE) and has demonstrated to bind activate macrophages vitro. Clinically, hyperferritinemia known be a biomarker for macrophage activation. The aim this study is clarify relationship anti-ribo clinical characteristics biomarkers including serum ferritin SLE.Clinical parameters laboratory data were measured active SLE (N = 127) our...