A5047690881- Cellular Mechanics and Interactions
- Microfluidic and Bio-sensing Technologies
- Advanced Sensor and Energy Harvesting Materials
- Electrospun Nanofibers in Biomedical Applications
- 3D Printing in Biomedical Research
- Inflammasome and immune disorders
- Orbital Angular Momentum in Optics
- Bone Tissue Engineering Materials
- Traditional Chinese Medicine Analysis
- Wound Healing and Treatments
- Neurological Disease Mechanisms and Treatments
- Neuroscience and Neural Engineering
- Flame retardant materials and properties
- Nerve injury and regeneration
- Micro and Nano Robotics
- Tactile and Sensory Interactions
- Holomorphic and Operator Theory
- Gout, Hyperuricemia, Uric Acid
- Aerogels and thermal insulation
- Advancements in Transdermal Drug Delivery
- Surface Modification and Superhydrophobicity
- Neuroinflammation and Neurodegeneration Mechanisms
- Nanomaterials and Printing Technologies
- Advanced Harmonic Analysis Research
- Antiplatelet Therapy and Cardiovascular Diseases
Xihua University
2024-2025
Southwest Jiaotong University
2019-2024
Chongqing Normal University
2023
China Pharmaceutical University
2020-2022
First People's Hospital of Chongqing
2022
Yangzhou Polytechnic Institute
2017
City University of Hong Kong
2012-2015
Cell adhesion-mediated piezoelectric stimulation provides a noninvasive method for in situ electrical regulation of cell behavior, offering new opportunities the design smart materials tissue engineering and bioelectronic medicines. In particular, surface potential is mainly dominated by inherent piezoelectricity biomaterial dynamic adhesion state cells. The development an efficient optimized material interface would have important implications regulation. Herein, we modified poled...
Biomimetic piezoelectric scaffolds provide a noninvasive method for in vivo cell regulation and tissue regeneration. Herein, considering the gradually varied properties of native cartilage bone tissues, we fabricated biomimetic electrospun poly(L-lactic acid) (PLLA) nanofibrous mats with gradient to induce integrated osteochondral differentiation rat mesenchymal stem cells (MSCs). Nanofibrous are polarized under electric fields linear variation strength generate piezoelectricity,...
Introduction Osteoarthritis (OA) remains a significant clinical challenge, necessitating improved strategies for cartilage repair. Stem cells and scaffolds have crucial roles in tissue repair regeneration. In this study, we comprehensively investigated the proliferation differentiation potential of infrapatellar fat pad stem (IFPSCs), synovium-derived (SDSCs), bone marrow (BMSCs) from unpretreated knee joints young rabbits, after decellularized extracellular matrix (dECM) deposition by cell...
Isolation from rare cells and deposition of sorted with high accuracy for further study are critical to a wide range biomedical applications. In the current paper, we report an automated cell manipulation tool combined optical tweezers uniquely designed microwell array, which functions recognition, isolation, assembly, transportation interesting cells. The array allows passive hydrodynamic docking cells, while offering opportunity inspect phenotypes spatio-temporal resolution based on...
Cell migration refers to the directional cell movement in response a chemoattractant gradient, key process that occurs wide variety of biological phenomena. protrusion force is generated by actin polymerization cell, which drives move toward stimulus as induced gradient. This paper presents new methodology for direct measurement utilizing robot-aided optical tweezer system. The functionalized beads are robotically trapped and placed near serve both stimulators probes. propels bead away from...
β-Tricalcium phosphate (β-TCP) is a bioactive material for bone regeneration, but its brittleness limits use as standalone scaffold. Therefore, continuous efforts are necessary to effectively integrate β-TCP into polymers, facilitating sturdy ion exchange cell regulation. Herein, novel semiembedded technique was utilized anchor nanoparticles onto the surface of elastic polymer, followed by hydrophilic modification with polymerization dopamine. Cell adhesion and osteogenic differentiation...
Cell-to-cell interactions are important for the regulation of various cell activities, such as proliferation, differentiation, and apoptosis. This paper presents an approach to studying cell-to-cell at a single-cell level through manipulating adhesions with optical tweezers. Experiments performed on leukemia cancer cells stromal demonstrate feasibility this method. After adhesion properties characterized, fluorescence intensity is used label study Wnt signaling pathway cells. The activities...
Flame-retardant surface treatments effectively reduce the fire hazard of polymeric foams but are plagued by high coating thickness and deterioration inherent thermal insulation. Constructing a nanostructure can significantly enhance insulation coatings, current methods usually rely on toxic solvents harsh conditions. Herein, we present facile eco-friendly strategy employing Cu2+-assisted aqueous phase separation (APS) for assembly nanostructured polyelectrolyte coatings in situ. Exploiting...
Incorporation of inorganic piezoelectric ceramic nanoparticles into a highly elastic polymer matrix is an effective method to develop self-powered sensors and energy harvesters. Herein, piezoelectrically enhanced nanogenerator (NG) obtained by dispersing lead-free BaTiO3 polydimethylsiloxane further surface-modifying with neoteric mosaic structure for sensing proposed. The composites fabricated through this facile low-cost approach exhibit voltage factor 1.5 relative those without...
Thixotropy-by-design bioink benefits enhancing printability and cell viability in 3D bioprinting.
This paper presents an approach to manipulating cell adhesions using optical tweezers for cell-to-cell interactions at single level. A case study of investigating the between leukemia cells and bone marrow stromal is reported. First, trapping force imposed on calibrated viability after tested verified. demonstrating feasibility proposed manipulation method. Second, properties K562 M210B4 from mouse HS5 human are characterized. Based characterization results, we classify into three categories...
Cell-to-cell interactions are complex processes that involve physical interactions, chemical binding, and biological signaling pathways. Identification of the functions special pathway in cell-to-cell interaction from very first contact will help characterize mechanism underlying advance new drug discovery. This paper reported a case study characterizing initial between leukemia cancer cells bone marrow stromal cells, through use an optical tweezers-based cell manipulation tool. Optical...