A5023534350- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Glioma Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Brain Metastases and Treatment
- Pituitary Gland Disorders and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Trigeminal Neuralgia and Treatments
- Facial Nerve Paralysis Treatment and Research
- Head and Neck Surgical Oncology
- Lung Cancer Research Studies
- Polymer crystallization and properties
- Polymer Nanocomposites and Properties
- Traumatic Brain Injury and Neurovascular Disturbances
- Additive Manufacturing and 3D Printing Technologies
- Bone Tumor Diagnosis and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Cerebrospinal fluid and hydrocephalus
- Oral and Maxillofacial Pathology
- Sarcoma Diagnosis and Treatment
- Teratomas and Epidermoid Cysts
- Electrospun Nanofibers in Biomedical Applications
- CNS Lymphoma Diagnosis and Treatment
Komaki City Hospital
2015-2025
Nissan (Japan)
1996-2014
University of Yamanashi
2005-2014
Takeda (Japan)
2005-2014
Nissan (United Kingdom)
2008-2014
Neurological Surgery
2002-2004
University of Pittsburgh
2002-2004
University of Pittsburgh Medical Center
2003-2004
Canon (Japan)
2004
National Cerebral and Cardiovascular Center
1986
Object Little is known about long-term outcomes, including tumor control and adverse radiation effects, in patients harboring vestibular schwannomas (VSs) treated with stereotactic radiosurgery > 10 years previously. The aim of this study was to confirm whether Gamma Knife surgery (GKS) for VSs continues be safe effective after treatment. Methods A total 440 VS (including neurofibromatosis Type 2) GKS between May 1991 December 2000 were evaluable. Of these, 347 (79%) underwent as an initial...
Object. Gamma knife surgery (GKS) has been a safe and effective treatment for vestibular schwannomas in both the short long term, although less is known about long-term outcomes past 10 years. The aim of this study was to clarify patients with treated using GKS based on techniques place early 1990s. Methods. Eighty harboring schwannoma (excluding neurofibromatosis Type 2) were between May 1991 December 1993. Among these, 73 assessed; seven lost follow up. median duration up 135 months. mean...
ABSTRACT OBJECTIVE: Many investigators have reported successful treatment of vestibular schwannomas with gamma knife radiosurgery (GKRS). However, long-term outcomes should be evaluated before concluding that GKRS is truly safe and effective for the schwannomas. METHODS: Between May 1991 December 1998, 346 consecutive patients (excluding those presenting neurofibromatosis Type 2) were treated GKRS. Of these, 317 assessed. Twenty-nine lost to follow-up within 5 years. RESULTS: The median...
Gamma Knife surgery (GKS) has been a safe and effective treatment for small- to medium-sized vestibular schwannomas (VSs) over relatively long-term outcomes. However, even with recent radiosurgical techniques, hearing results following GKS remain unsatisfactory. The purpose of this study was evaluate the preservation rate as well factors related in patients VSs serviceable who were treated GKS.Among Gardner-Robertson (GR) Class I or II between 1991 2009, 117 evaluable via periodic MR imaging...
Stereotactic radiosurgery has been used for patients with high-risk cavernous malformations of the brain. We performed symptomatic, imaging-confirmed hemorrhages which resection was believed to be associated high risk. This study examines long-term hemorrhage rate after radiosurgery.We reviewed data obtained before and gamma knife on 82 treated between 1987 2000. Most had multiple from brainstem or diencephalic malformations. Follow-up were examined identify hemorrhages, an overall...
The authors analyzed the long-term outcomes of gamma knife surgery (GKS) for residual or recurrent craniopharyngiomas after microsurgery and effects dose reduction.A total 107 patients with were treated GKS at Komaki City Hospital during past 12 years, 98 followed up 6 to 148 months (mean 65.5 months). mean tumor diameter volume 18.8 mm 3.5 ml, respectively. These tumors a maximal 21.8 Gy margin 11.5 by using 4.5 isocenters. Final overall response rates as follows: complete 19.4%, partial...
The efficacy of stereotactic intracavitary irradiation with phosphorus-32 ((32)P) for patients cystic craniopharyngiomas was assessed on the basis patient survival, tumor control, and visual endocrinological function before after treatment. Limited data are available regarding long-term outcomes.Forty-nine were treated (32)P irradiation. Of these, 25 had no prior treatment as primary treatment, 24 residual or recurrent cysts. At time irradiation, 34 adults, 15 children younger than 16 years...
Object The aim of this study was to evaluate long-term outcomes, including tumor control and neurological function, in patients with cavernous sinus meningiomas treated using Gamma Knife surgery (GKS). Methods One hundred fifteen meningiomas, excluding atypical or malignant were GKS between 1991 2003. Forty-nine (43%) underwent as the initial treatment. mean volume 14 cm 3 , maximum margin doses applied 27 13 Gy, respectively. median follow-up period 62 months. During follow-up, 111 able be...
Object The purpose of this study was to evaluate radiosurgical outcomes in skull base chordomas and chondrosarcomas, determine which tumors are appropriate for stereotactic radiosurgery as adjuvant therapy following maximum tumor resection. Methods Thirty-seven patients (48 lesions) were treated using Gamma Knife surgery (GKS); 27 had chordomas, seven three radiologically diagnosed chordomas. mean volume 20 ml, the marginal doses 28 14 Gy, respectively. follow-up period 97 months from...
OBJECTIVE: Stereotactic radiosurgery has been accepted as a safe and effective treatment in patients harboring vestibular schwannoma. However, during follow-up, tumor expansion induced by high-dose irradiation can occur. Tumor is more likely to be transient, but this phenomenon causes some confusion regarding whether further should performed. Our purpose was clarify what type of requires additional treatment. METHODS: Between May 1991 December 1998, 346 with schwannoma, excluding two...
To determine the limiting dose to optic apparatus in single-fraction irradiation patients with craniopharyngioma treated gamma knife radiosurgery (GKRS).One hundred 109 craniopharyngiomas GKRS were evaluated a median follow-up period of 68 months. Tumor volume varied from 0.1 36.0 (median, 3.3) cm. Marginal doses 10 18 11.4) Gy. Maximum any part 2 10) Gy.The actuarial 5- and 10-year overall rates survival tumor progression after 93% 88%, respectively. Similarly, progression-free 62% 52%,...
Radiosurgery is increasingly being used to treat pineal region tumors, either as an additional therapy after conventional treatments or a primary treatment. We report our experience with Gamma Knife radiosurgery (GKRS) for the treatment of and related tumors. Forty-nine patients underwent GKRS tumors (n = 74) between February 1992 September 2007. The diagnosis was germ cell (GCTs) in 38 (53 tumors), parenchymal (PPTs) 9 (19 unknown 2 (2 tumors). mean volume 3.3 ml (range 0.1–22 ml) GCT cases...
The aim of this study was to explore the efficacy and safety stereotactic radiosurgery for patients with facial nerve schwannomas (FNSs).This a multiinstitutional retrospective analysis 42 FNSs treated Gamma Knife surgery (GKS) at 1 10 medical centers Japan Leksell Society (JLGK1301). median age 50 years. Twenty-nine underwent GKS as initial treatment, 13 had previously undergone surgery. At time GKS, 33 (79%) some degree palsy, 21 (50%) did not retain serviceable hearing. Thirty-five (83%)...
OBJECTIVE In order to obtain better local tumor control for large (i.e., > 3 cm in diameter or 10 volume) brain metastases (BMs), 3-stage and 2-stage Gamma Knife surgery (GKS) procedures, rather than a palliative dose of stereotactic radiosurgery, have been proposed. Here, authors conducted retrospective multi-institutional study compare treatment results between GKS BMs. METHODS This involved 335 patients from 19 facilities Japan. Major inclusion criteria were 1) newly diagnosed BMs, 2)...
BACKGROUND AND OBJECTIVES: Transient neurological deficits (TNDs) in patients with chronic subdural hematoma (CSDH), such as fluctuating aphasia, hemiparesis, or sensory disturbances, present diagnostic and treatment challenges their pathophysiology remains unclear. The aim of this study was to investigate the association between specific MRI findings TNDs CSDH explored relationship through intraoperative observation. METHODS: We retrospectively evaluated 72 who underwent preoperative among...
BACKGROUND The management of recurrent brain metastases after initial stereotactic radiosurgery (SRS) remains challenging, with high local recurrence rates following salvage surgery. While preoperative SRS has shown promise for newly diagnosed metastases, its application in post-SRS recurrences is largely unexplored. OBSERVATIONS authors treated three patients using re-irradiation followed by resection. Gamma Knife was performed at marginal doses 16–18 Gy, resection within 24–48 hours. Local...
Stereotactic radiosurgery has become an important and minimally invasive alternative for patients with refractory trigeminal neuralgia. When a second procedure is necessary, the outcomes are unknown. The degree of pain relief morbidity after repeat were studied.Thirty-one underwent gamma knife because unsatisfactory or unsustained first procedure. Twenty-seven assessable at median follow-up periods 42.7 20.4 months procedures, respectively. Most had undergone multiple previous operations...
✓ Sinus histiocytosis or Rosai—Dorfman disease (RDD) is a rare idiopathic histioproliferative disorder typically characterized by painless cervical lymphadenopathy, fever, and weight loss. Extranodal, intracranial uncommon. In this report the authors describe first case of RDD treated with stereotactic radiosurgery after resection. This 52-year-old man known presented 7-day course headache, diplopia, left facial paresthesias, difficulty swallowing. No cranial nerve deficits were evident on...
Radiosurgery is an appealing alternative management strategy for selected patients with biopsy-proved pineal parenchymal tumors. The purpose of this report was to clarify its role in conjunction other surgical, radiation, and medical approaches.We retrospectively evaluated 16 who had undergone radiosurgery as the primary or adjuvant treatment Ten (62.5%) pineocytomas, two (12.5%) mixed pineocytoma pineoblastoma, four (25%) pineoblastomas. mean marginal dose 15 Gy, tumor volume 5.0 cm(3)....
Abstract In this paper, we describe the performances of two types new electron injection layers (EILs) for OLEDs using Cesium Carbonate (Cs 2 CO 3 ). The first is a thin Cs , and other, co‐evaporated layer transport material . Devices with these EILs exhibited better electrical properties Al, Ag or Au cathode than devices LiF as EIL Al cathode. addition, have measured characteristics top‐emission confirmed effectiveness even from ITO
Object Information on outcomes of Gamma Knife surgery (GKS) for patients harboring trigeminal schwannomas is limited because these tumors are rare. The authors evaluated tumor control and functional in who underwent GKS to clarify the efficacy this treatment. Methods Forty-two with but no evidence neurofibromatosis Type 2 were treated at Komaki City Hospital between November 1991 December 2003. Of these, 37 assessed. mean volume was 10 cm 3 . maximum radiation dose directed 27.9 Gy margin...
Object The aim of this study was to evaluate the results radiosurgery in patients with facial schwannoma. Methods population consisted 14 patients, six men and eight women, a mean age 45.4 years. Most had presented palsy (11 patients) and/or hearing disturbance (nine patients). Prior treatment nine cases tumor resection or biopsy. Tumor volume ranged from 0.98 20.8 cm 3 , 5.5 . maximum radiation dose margin used for were 24.0 12.9 Gy, respectively. During follow-up period 31.4 months (range...
The aim of this study was to evaluate the outcomes in patients with convexity, parasagittal, or falcine meningiomas treated using Gamma Knife surgery (GKS) and determine management strategy considering a risk radiation-induced edema.One hundred twelve who harbored 125 were assessed. Forty-six underwent GKS as initial treatment. median tumor diameter 25 mm, volume 8 cm(3). maximum margin doses 30 16 Gy, respectively.The follow-up period 72 months. actuarial 5- 10-year progression-free...