A5057756268- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Moyamoya disease diagnosis and treatment
- Meningioma and schwannoma management
- Cardiovascular Health and Disease Prevention
- Neurological Complications and Syndromes
- Traumatic Brain Injury and Neurovascular Disturbances
- Liver Disease Diagnosis and Treatment
- Brain Metastases and Treatment
- Diabetes and associated disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Pituitary Gland Disorders and Treatments
- Cerebrospinal fluid and hydrocephalus
- Stroke Rehabilitation and Recovery
- Liver Diseases and Immunity
- Growth Hormone and Insulin-like Growth Factors
- Management of metastatic bone disease
- IgG4-Related and Inflammatory Diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
National Cerebral and Cardiovascular Center
2014-2025
Kagoshima University
2024
Kyoto University
1983-2024
Oita University
2009-2011
Takatsuki Red Cross Hospital
2004
Osaka Medical and Pharmaceutical University
1993
Toyama Prefectural Central Hospital
1988
Radiation has been shown to enhance intercellular communication in the skin and lungs through an increase of connexin43 (Cx43) expression. If analogous Cx43 up-regulation is induced diseased heart, it would provide a new perspective radiation therapy for arrhythmias. The aim present study test this hypothesis.Non-transmural myocardial infarction (MI) was created 24 rabbits by microsphere injection into coronary arteries. Twenty-four without MI were used as controls. Targeted external heavy...
OBJECTIVE In order to obtain better local tumor control for large (i.e., > 3 cm in diameter or 10 volume) brain metastases (BMs), 3-stage and 2-stage Gamma Knife surgery (GKS) procedures, rather than a palliative dose of stereotactic radiosurgery, have been proposed. Here, authors conducted retrospective multi-institutional study compare treatment results between GKS BMs. METHODS This involved 335 patients from 19 facilities Japan. Major inclusion criteria were 1) newly diagnosed BMs, 2)...
The aim of this study was to retrospectively compare high-resolution CT findings among cryptogenic organizing pneumonia (COP) patients with normal and elevated serum KL-6 levels. Chest scans performed between April 1999 2007 in 20 COP a level 17 an were evaluated by two chest radiologists. the either or mainly consisted consolidation (n = n 13, respectively) followed ground-glass opacity 11 respectively). Traction bronchiectasis architectural distortion significantly more frequent than those...
Objective The optimal treatment for a craniopharyngioma has been controversial. Complete resection is ideal, but it difficult to obtain total in many cases because of intimate proximity critical structures such as the optic pathway, hypothalamus, and pituitary gland. A growing number studies have demonstrated utility radiosurgery controlling residual or recurrent craniopharyngioma. However, most them are small series. aim this multi-institutional study was clarify efficacy safety Gamma Knife...
<h3>BACKGROUND AND PURPOSE:</h3> Radiation-induced changes can occur after stereotactic radiosurgery for brain AVMs, potentially causing symptomatic complications. We evaluated the incidence of such and efficacy repeat gamma knife incompletely obliterated AVMs. <h3>MATERIALS METHODS:</h3> retrospectively 150 patients who underwent AVMs between 2002 2020; twenty-five further radiosurgical procedures recorded median margin doses at first (median, 20 Gy; range, 12–23 AVM volume, 0.026–31.3 mL)...
This study aimed to compare thin-section CT images from sarcoidosis patients who had either normal or elevated serum KL-6 levels.101 with underwent examinations of the chest and measurements between December 2003 November 2008 were retrospectively identified. The group comprised 75 (23 male, 52 female; aged 19-82 years, mean 54.1 years) levels (152-499 U ml(-1), 305.7 ml(-1)) 26 (7 19 19-75 54.3 (541-2940 802.4 ml(-1)). Two radiologists, unaware levels, independently interpreted for...
Clazosentan (CLA) reduces cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH). However, adverse events including pulmonary edema were reported. We examined whether the strict management of fluid balance and improves patient outcomes. Patients with aSAH between 2020 2023 included. They divided into pre-CLA (before CLA approval) post-CLA (after groups. The patients in group further post-CLA1 change management) post-CLA2 change) To achieve 0–500 ml/day according to modified...
Background and purpose Intracranial aneurysm growth is a significant risk factor for rupture; however, few aneurysms remain unruptured long periods, even after growth. Here, we identified hemodynamic features associated with aneurysmal rupture Materials methods We analyzed nine middle cerebral artery that grew during the follow-up period using computational fluid dynamics analysis. Growth patterns of were divided into homothetic (Type 1), de novo bleb formation 2), enlargement 3)....
Malignant transformation of vestibular schwannoma (VS) after Gamma Knife Surgery (GKS) was extremely rare, but potentially serious complication leading to poor prognosis. Small number cases have been reported they are limited single case report. This article presents a cerebellopontine angle tumor in 54-year-old man who had right-sided hearing disturbance which lasted for 11 years. The patient underwent resection via retrosigmoid approach May 2004 at another hospital, and subtotal removal...
Abstract Background Hashimoto’s disease has reportedly been associated with stroke; however, cerebrovascular morphology and clinical course remain poorly documented. The present study aimed to determine the angiographic features outcomes of intracranial arterial stenosis (IAS) in a retrospective cohort. Methods Overall, 107 adult patients IAS were screened for anti-thyroid antibodies; these, 26 tested positive. 42 affected hemispheres classified into subgroups according steno-occlusion site...
近年の多施設共同前向き研究によって, 未破裂脳動脈瘤の自然予後が明らかになるとともに, 日本人の高い破裂率が立証された. 臨床現場では患者の予後改善のために, これら最新のデータを踏まえた治療介入判断が必要であるが, 一方で個々の症例に特有の種々の問題があり, 臨床医には総合的な「判断と行動」が求められる. また, 大規模研究データに基づいた事前介入のみでは国内SAH総数を大幅削減することは困難であり, 単純に「みつけて治す」だけでない, 新たな診断・治療概念の登場を待たなくてはならない.