- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Moyamoya disease diagnosis and treatment
- Neurological Complications and Syndromes
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Meningioma and schwannoma management
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Central Venous Catheters and Hemodialysis
- Cerebral Venous Sinus Thrombosis
- Aortic aneurysm repair treatments
- Vascular Procedures and Complications
- Cerebrovascular and genetic disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Glioma Diagnosis and Treatment
- Intraoperative Neuromonitoring and Anesthetic Effects
- Management of metastatic bone disease
- Polyoxometalates: Synthesis and Applications
- Vasculitis and related conditions
- Trigeminal Neuralgia and Treatments
- Maternal and fetal healthcare
- Aortic Disease and Treatment Approaches
- Advanced Electron Microscopy Techniques and Applications
National Cerebral and Cardiovascular Center
2016-2025
Kyoto University
2024-2025
Kagoshima University
2024
Juntendo University
2010
Long-term outcomes are unknown in patients with asymptomatic moyamoya disease. In this report, we aimed to clarify their 5-year risk of stroke and its predictors.We conducting a multicenter, prospective cohort study (Asymptomatic Moyamoya Registry) Japan. Participants were eligible if they 20 70 years, had bilateral or unilateral disease, experienced no episodes suggestive TIA stroke; functionally independent (modified Rankin Scale score 0-1). Demographic radiological information was...
OBJECTIVE Transient neurological symptoms are frequently observed during the early postoperative period after direct bypass surgery for moyamoya disease. Abnormal signal changes in cerebral cortex can be seen MR images. The purpose of this study was to reveal radiological features "cortical hyperintensity belt (CHB) sign" FLAIR images and verify its relationship transient events (TNEs) regional blood flow (rCBF). METHODS A total 141 hemispheres 107 consecutive patients with disease who had...
BACKGROUND Although bypass surgery can reduce rebleeding risk in hemorrhagic moyamoya disease, the remaining after is not negligible. We hypothesized that postoperative persistence of periventricular anastomosis (PA), a fragile collateral manifestation, associated with rebleeding. METHODS This retrospective cohort study included patients disease who underwent direct at 2 institutions presentation. Either presence or absence PA was radiologically determined by grading each subtype,...
OBJECTIVE Hyperperfusion syndrome (HPS) is a notable complication that causes various neurological symptoms after superficial temporal artery (STA)-middle cerebral (MCA) bypass surgery for moyamoya disease (MMD). The authors used intraoperative indocyanine green (ICG) videoangiography to measure the change in microvascular transit time (MVTT) surgery. An analysis was then conducted identify correlation between MVTT and presence of postoperative HPS. METHODS This study included 105...
We described pregnancy and delivery management in 9 patients with cerebral arteriovenous malformation (AVM). Six presented intracerebral hemorrhage (ICH) during (first hemorrhagic episode); 2 headache; 1 patient incidental detection of AVM. In the 3 unruptured AVM, diagnosis was made before pregnancy. 6 who ICH, AVM removal performed One required emergency surgery for mass effect hematoma, Spetzler-Martin grade I II AVMs underwent elective prevention rebleeding. Radiosurgery multiple after...
Abstract Aim To clarify the perinatal outcomes in pregnancy complicated with intracranial arteriovenous malformation (i‐AVM). Methods A retrospective study was performed 36 pregnancies by i‐AVM from 1981 to 2013 at one institution. Results In total, 6 women miscarried, and 30 had live births. The median (range) gestational age delivery 38 (24–40) weeks; 11 cases experienced initial rupture during (first, second third trimester: 18%, 64% respectively). At onset, 4 a Glasgow Coma Scale ≤10, 10...
<h3>BACKGROUND AND PURPOSE:</h3> Radiation-induced changes can occur after stereotactic radiosurgery for brain AVMs, potentially causing symptomatic complications. We evaluated the incidence of such and efficacy repeat gamma knife incompletely obliterated AVMs. <h3>MATERIALS METHODS:</h3> retrospectively 150 patients who underwent AVMs between 2002 2020; twenty-five further radiosurgical procedures recorded median margin doses at first (median, 20 Gy; range, 12–23 AVM volume, 0.026–31.3 mL)...
A 15-year-old boy presented with an anaplastic supratentorial ependymoma causing massive intratumoral calcification, without contributory medical and family history, manifesting as persistent headache for 2 months. Physical examination found no neurological deficit except visual defect in the right lower quadrant, intact acuity. Blood showed abnormalities. Cranial computed tomography revealed a huge calcified mass left parietooccipital lobe, extensive perilesional brain edema. radiography...
Background and purpose Intracranial aneurysm growth is a significant risk factor for rupture; however, few aneurysms remain unruptured long periods, even after growth. Here, we identified hemodynamic features associated with aneurysmal rupture Materials methods We analyzed nine middle cerebral artery that grew during the follow-up period using computational fluid dynamics analysis. Growth patterns of were divided into homothetic (Type 1), de novo bleb formation 2), enlargement 3)....
Clazosentan (CLA) reduces cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH). However, adverse events including pulmonary edema were reported. We examined whether the strict management of fluid balance and improves patient outcomes. Patients with aSAH between 2020 2023 included. They divided into pre-CLA (before CLA approval) post-CLA (after groups. The patients in group further post-CLA1 change management) post-CLA2 change) To achieve 0–500 ml/day according to modified...
Abstract Background Hashimoto’s disease has reportedly been associated with stroke; however, cerebrovascular morphology and clinical course remain poorly documented. The present study aimed to determine the angiographic features outcomes of intracranial arterial stenosis (IAS) in a retrospective cohort. Methods Overall, 107 adult patients IAS were screened for anti-thyroid antibodies; these, 26 tested positive. 42 affected hemispheres classified into subgroups according steno-occlusion site...
要旨: 【目的】近年脳血管内治療は普及の一途をとげているが,病変へのアクセス時に,ガイディングカテーテル(GC)を母血管に干渉せず留置できるかどうかは治療の成否に関与する重要な因子の一つである.そこで,GC を留置する際に機械的血管攣縮(mechanical vasospasm; mVS)を惹起する因子について検討した.【方法】対象は2012 年8 月1 日より2014 年7 月31 日までの2 年間に未破裂脳動脈瘤に対しコイル塞栓術を施行した連続64 例とし後方視的に検討した.mVS の定義として,GC を留置した母血管径が25%以上狭小化するものとした.【結果】mVS は24 例(38%)に認め,そのうちGC のサイズ変更を要したものは5 例,その他の症例では先端位置を変えることで攣縮所見は全例軽快した.mVS と関連する因子として,より年齢が若いこと(p<0.001),女性(p=0.03),高血圧でないもの(p=0.03)を認めた.Body Mass Index,Adjunctive technique の有無,治療後のDWI...
The rate of recanalization after coil embolization for unruptured intracranial aneurysms (UIAs) is reported to occur around 11.3%-49%. This study aims investigate the factors that influence UIAs in our institution. We retrospectively investigated 307 296 patients treated at institution between April 2004 and December 2016. stent-used cases were excluded. Cerebral angiography 3D time-of-flight magnetic resonance (TOF MRA) used evaluation postoperative occlusion status. Volume ratio (VER),...