A5006399718- Meningioma and schwannoma management
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Lung Cancer Research Studies
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Bone and Dental Protein Studies
- Neurofibromatosis and Schwannoma Cases
- Cerebrovascular and Carotid Artery Diseases
- Neonatal and fetal brain pathology
- dental development and anomalies
- Moyamoya disease diagnosis and treatment
- Periodontal Regeneration and Treatments
- Stress Responses and Cortisol
- Temporomandibular Joint Disorders
- Botulinum Toxin and Related Neurological Disorders
- Myofascial pain diagnosis and treatment
- Laser Applications in Dentistry and Medicine
- Dental Education, Practice, Research
- Neurobiology of Language and Bilingualism
- Genetic Neurodegenerative Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Salivary Gland Disorders and Functions
- Facial Nerve Paralysis Treatment and Research
Chiba Cerebral and Cardiovascular Center
2012-2024
Neurological Surgery
2009-2022
Chiba University
2020-2022
Nippon Dental University
2009-2012
University of California, San Francisco
2009-2010
The purpose of this study was to identify and compare the perspectives dental students towards their career choice education in Japan Sweden. One hundred fourteen from Nippon Dental University, 43 Karolinska Institutet, Sweden participated study. Information derived a self-answered questionnaire consisting five items for six education. Chi-square test Wilcoxon signed-rank were used comparison. Significant differences detected 10 between two countries. Regarding motivation choice, 44% Swedish...
OBJECTIVE In order to obtain better local tumor control for large (i.e., > 3 cm in diameter or 10 volume) brain metastases (BMs), 3-stage and 2-stage Gamma Knife surgery (GKS) procedures, rather than a palliative dose of stereotactic radiosurgery, have been proposed. Here, authors conducted retrospective multi-institutional study compare treatment results between GKS BMs. METHODS This involved 335 patients from 19 facilities Japan. Major inclusion criteria were 1) newly diagnosed BMs, 2)...
Abstract Introduction Historical reservations regarding stereotactic radiosurgery (SRS) for small-cell lung cancer (SCLC) brain metastases include concerns short-interval and diffuse central nervous system (CNS) progression, poor prognoses, increased neurological mortality specific to SCLC histology. We compared SRS outcomes non-small cell (NSCLC) where is well established. Methods Multicenter first-line NSCLC from 2000 2022 were retrospectively collected (n = 892 SCLC, n 4785 NSCLC). Data...
Mice subjected to traumatic brain injury at postnatal day 21 show emerging cognitive deficits that coincide with hippocampal neuronal loss. Here we consider glutathione peroxidase (GPx) activity as a determinant of recovery in the injured immature brain.Wild-type and transgenic (GPxTg) mice overexpressing GPx were or sham surgery 21. Animals killed acutely (3 24 hours after injury) assess oxidative stress cell hippocampus 4 months behavioral assessments.In brains, reduction markers including...
There is increasing evidence that the inflammatory response differs in injured developing brain as compared to adult brain. Here we cerebral blood flow and profiled mice had been subjected traumatic injury (TBI) at postnatal day (P)21 or adulthood. Relative flow, determined by laser Doppler, revealed a 30% decrease immediately after followed prominent hyperemia between 7 35 days both age groups. The animals were euthanized 1–35 brains prepared for immunolocalization quantification of CD45-,...
The authors assessed the subjective symptoms of temporomandibular disorders (TMDs) in 167 young patients using self-reported forms, with five ratings for pain intensity and six difficulty activities daily living (ADL), to compare TMD according gender three age groups: group 1: 6- 12-year-olds (juvenile); 2: 13- 15-year-olds (early adolescent); 3: 16- 18-year-olds (late adolescent). No significant differences were found among groups, except headache neck 3. Pain tightness jaw/face, headache,...
Background: In temporal lobe epilepsy (TLE), estimating the potential risk of language dysfunction before surgery is a necessary procedure. Functional MRI (fMRI) considered most useful to determine lateralization noninvasively. However, there are no standardized fMRI protocols, and several issues remain unresolved. particular, tasks normally used predominantly active paradigms that require overt participation patients, making assessment difficult for pediatric patients or with intellectual...
International Journal of Paediatric Dentistry 2010; 20: 458–465 Aim. To compare subjective symptoms among three diagnostic subgroups young patients with temporomandibular disorders (TMDs). Design. We comprehensively examined 121 TMDs (age ≤20 years; 90 female and 31 male patients) who completed self‐reported forms for assessing symptoms, which consisted five items on pain intensity in the orofacial region six level difficulty activities daily living (ADL) (rating scale, 0–10). They were...
OBJECTIVE The neurological prognostic score (NPS) was recently proposed as a means for predicting outcomes, such the preservation of function and prevention death, in brain metastasis patients treated with Gamma Knife radiosurgery (GKRS). NPS consists 2 groups: Group A were expected to have better B poorer outcomes. robustness tested various situations. METHODS In total, 3040 metastases that GKRS analyzed. cumulative incidence loss independence (i.e., deterioration) estimated using competing...
Abstract The salivary alpha‐amylase (sAA) level is widely considered a marker of psychological stress. For clinical applicability, its characteristics should be examined under normal conditions. aims this study were to investigate the circadian rhythm, daily variation in week and sex difference sAA sublingual saliva resting condition, for which 6 individuals, 11 individuals 30 age‐matched women men, respectively, enrolled. individual levels measured once every hour from 10:00 16:00 (7...
To assess the long-term outcomes of intracranial dural arteriovenous fistula (DAVF) treated with stereotactic radiosurgery (SRS) alone or embolization and SRS (Emb-SRS) to develop a grading system for predicting DAVF obliteration. This multi-institutional retrospective study included 200 patients Emb-SRS. We investigated obliteration rate obliteration-associated factors. developed new estimate rate. Additionally, we compared Emb-SRS by using propensity score matching. The 3- 4-year rates...
Brain metastasis is rare in ovarian cancer patients. The results of Gamma Knife radiosurgery (GKRS) for the treatment patients with brain metastases from were retrospectively analyzed to derive efficacy and prognostic factors survival local tumor control. Further histopathological analysis was also performed.
The natural history of intracranial arterial dissection (ICAD) is not known precisely, so that treatment strategy hard to determine in some cases. We examined the clinical features, and long-term outcomes ICAD ischemic onset. Among 214 consecutive patients with [199 vertebrobasilar system (VBs) 15 internal carotid (ICs)], 76 presented brain ischemia. Those were classified into 2 groups: 63 VBs 13 ICs. analyzed age, site dissection, progression or recurrence ischemia, medical surgical...
OBJECTIVE Due to the heterogeneous definitions of tumor regrowth and various volume distributions, nature small remnants after vestibular schwannoma (VS) surgery appropriate timing adjuvant stereotactic radiosurgery for these remain unclear. In this study, growth potential (< 1 cm 3 ) VS was compared with that treatment-naïve (TN) VSs. METHODS This retrospective single-center study included 44 patients following subtotal resection (STR) a large (remnant group) 75 TN ; group). A 20% change...