A5106975219- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Hepatitis C virus research
- Shoulder and Clavicle Injuries
- Health Systems, Economic Evaluations, Quality of Life
- SARS-CoV-2 and COVID-19 Research
- Statistical Methods in Clinical Trials
- Salivary Gland Disorders and Functions
- Bone fractures and treatments
- Liver Disease Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Lung Cancer Treatments and Mutations
- Hernia repair and management
- Sepsis Diagnosis and Treatment
- Appendicitis Diagnosis and Management
- Asthma and respiratory diseases
- Elbow and Forearm Trauma Treatment
- Nerve Injury and Rehabilitation
- Pelvic and Acetabular Injuries
- Cardiac Arrest and Resuscitation
- Meta-analysis and systematic reviews
- Aortic aneurysm repair treatments
- Hepatitis B Virus Studies
Hôpitaux Universitaires de Strasbourg
2016-2025
Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie
2016-2025
Université de Strasbourg
2016-2025
Service de la Santé Publique
2024
Hôpital Civil, Strasbourg
2006-2023
Weatherford College
2023
Centre National de la Recherche Scientifique
2019-2022
Museum of Heilongjiang Province
2021
Hôpital d'Hautepierre
2020
Collaborative Group (United States)
2020
Background Brain MRI parenchymal signal abnormalities have been associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Purpose To describe the neuroimaging findings (excluding ischemic infarcts) in patients disease 2019 (COVID-19) infection. Materials and Methods This was a retrospective study of evaluated from March 23, 2020, to April 27, at 16 hospitals. Inclusion criteria were (a) positive nasopharyngeal or lower tract reverse transcriptase polymerase chain reaction...
To describe neuroimaging findings and to report the epidemiologic clinical characteristics of patients with coronavirus disease 2019 (COVID-19) neurologic manifestations.In this retrospective multicenter study (11 hospitals), we included 64 confirmed COVID-19 manifestations who underwent a brain MRI.The cohort 43 men (67%) 21 women (33%); their median age was 66 (range 20-92) years. Thirty-six (56%) MRIs were considered abnormal, possibly related severe acute respiratory syndrome...
BackgroundAssessment of the kinetics SARS-CoV-2 antibodies is essential in predicting risk reinfection and durability vaccine protection.MethodsThis a prospective, monocentric, longitudinal, cohort clinical study. Healthcare workers (HCW) from Strasbourg University Hospital were enrolled between April 6th May 7th, 2020 followed up to 422 days. Serial serum samples tested for against Receptor Binding Domain (RBD) spike protein nucleocapsid (N) characterize incidence reinfection....
Our objective was to evaluate the relationship between cannabis use and ischemic stroke in a young adult population.Forty-eight consecutive patients admitted for acute participated study. First-line screening performed, including blood tests, cardiovascular investigations, urine analysis cannabinoids. If no etiology found, 3D rotational angiography cerebrospinal fluid were performed. A control planned through neurovascular imaging within 3 6 months.In this series, there multifocal...
We sought to determine whether assessing D-Dimer might be helpful for the management of acute aortic dissection (AAD).Single-center retrospective case-control study.University Hospital Strasbourg France.Patients were 94 consecutive patients admitted our institution with confirmed AAD and in whom test had been performed at presentation. These matched controls presenting clinical suspicion dissection, which was later ruled out.Patient characteristics course analyzed.Ninety-three (99%) elevated...
Background In March 2020, the COVID-19 outbreak was declared a pandemic by World Health Organization. Aim Our objective to identify risk factors predictive of severe disease and death in France. Methods this prospective cohort study, we included patients ≥ 18 years old with confirmed COVID-19, hospitalised Strasbourg Mulhouse hospitals (France), 2020. We respectively compared who developed (admission an intensive care unit (ICU) or death) died, those did not, day 7 after hospitalisation....
Abstract Background High‐molecular‐weight ( HMW ) proteins and low‐molecular‐weight LMW chemicals can cause occupational asthma OA although few studies have thoroughly compared the clinical, physiological, inflammatory patterns associated with these different types of agents. The aim this study was to determine whether induced by agents shows distinct phenotypic profiles. Methods Clinical functional characteristics, markers airway inflammation were analyzed in an international, multicenter,...
Objectives No immunomodulatory drug has been approved for primary Sjögren’s syndrome, a systemic autoimmune disease affecting 0.1% of the population. To demonstrate efficacy targeting interleukin 6 receptor in patients with syndrome-related complications. Methods Multicentre double-blind randomised placebo-controlled trial between 24 July 2013 and 16 2018, follow-up 44 weeks, involving 17 referral centres. Inclusion criteria were syndrome according to American European Consensus Group score...
Abstract We measured anti-spike (S), nucleoprotein (N), and neutralizing antibodies in sera from 308 healthcare workers with a positive reverse-transcription quantitative polymerase chain reaction result for severe acute respiratory syndrome coronavirus 2 mild disease, collected at timepoints up to 6 months after symptom onset. At month 1, anti-S -N antibody levels were higher male participants aged >50 years body mass index (BMI) >25 kg/m2. 3–6, anti-N detected 99% 59% of...
ABSTRACT Cat scratch disease (CSD) is mostly due to Bartonella henselae after inoculation of the organism through a skin injury. Since causative bacteria cannot be easily cultured from human lymph node samples, diagnosis usually relies on epidemiological, clinical, histological, and serological criteria (classical criteria). A study was performed determine diagnostic value PCR analysis for detection B. CSD its place in strategy alongside classical criteria. Over 7-year period, biopsy...
The Fuhrman system is the most widely used nuclear grading for renal cell carcinoma (RCC). Although grade accepted as a significant prognostic factor, its reproducibility, reported in limited number of series available literature, appears to be low.Between 1980 and 1990, 255 cases RCC (pT1-3bN0M0) were treated with radical nephrectomy at Department Urology, University Hospital, Strasbourg, France. In retrospective multicenter study, 3 pathologists independently classified 241 these according...
<h3>Objective</h3> Although direct-acting antiviral agents (DAAs) have markedly improved the outcome of treatment in chronic HCV infection, there continues to be an unmet medical need for therapies difficult-to-treat patients as well liver graft infection. Viral entry is a promising target therapy. <h3>Design</h3> Aiming explore role inhibitors future clinical development, we investigated efficacy and toxicity combination with DAAs or other host-targeting (HTAs). Screening large series...
Cerebral aspergillosis is associated with a significant morbidity and mortality rate. The imaging data present different patterns no full consensus exists on typical characteristics of the cerebral lesions. We reviewed MRI findings in 21 patients correlated them to immune status neuropathological when tissue was available. lesions were characterized by their number, topography, signal. Dissemination brain resulted from direct spread paranasal sinuses 8 patients, 6 being immunocompetent....
Background: Early repair of isolated supraspinatus tears could prevent further deterioration the rotator cuff; however, there is no consensus on management such because a lack long-term outcome studies. The purposes this study were to report 10-year outcomes repairs and investigate factors that favor healing recovery. Methods: We retrieved records all 511 patients who, in 2003, underwent full-thickness tears, performed by 15 surgeons at centers. In 2014, asked return for evaluation minimum...