A5023022828- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Liver Disease Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Anesthesia and Sedative Agents
- Cancer, Lipids, and Metabolism
- Glioma Diagnosis and Treatment
- Angiogenesis and VEGF in Cancer
- Cancer Research and Treatments
- RNA Research and Splicing
- Phytochemicals and Antioxidant Activities
- Liver Disease and Transplantation
- Cancer-related Molecular Pathways
- Air Quality and Health Impacts
- Cancer Mechanisms and Therapy
- Gastric Cancer Management and Outcomes
- Phytochemistry and Biological Activities
- Organ Transplantation Techniques and Outcomes
- Cell Adhesion Molecules Research
- Ginger and Zingiberaceae research
- Bioactive natural compounds
- Hedgehog Signaling Pathway Studies
- Neuroscience of respiration and sleep
Nanjing Medical University
2013-2025
Yangtze University
2025
Jiangsu Province Hospital
2022-2025
Kunming University of Science and Technology
2019-2024
Hebei Medical University
2021-2024
Second Hospital of Hebei Medical University
2021-2024
Tianjin Medical University
2024
Peking University
2024
Peking University Third Hospital
2014-2024
Tongren Hospital
2024
The tender leaves and buds of<italic>Vaccinium dunalianum</italic>Wight have been traditionally processed as folk tea, known Que Zui tea (QT), with a wide range of benefits to humans.
SUMMARY The studies presented herein examined the mechanism(s) whereby sirolimus (SRL) and cyclosporin (CsA) act synergistically to block allograft rejection. Combination index (CI=1 reflects additive, CI&lt;1 antagonistic, synergistic, effects) analysis documented potent synergism between SRL CsA Combinations of two drugs produced synergistic prolongation heart (CI=0.001–0.2) or kidney (CI=0.03–0.5) survival at SRL/CsA ratios ranging from 1:12.5 1:200. Pharmacokinetic individual showed...
Following the publication of this paper, and subsequently to a corrigendum (DOI: 10.3892/mmr.2022.12738) that was intended address issue pair duplicated data panels in Fig. 2C, it drawn Editor's attention by concerned reader there regrettably remained issues with overlapping revised version 2 provided authors; furthermore, were included corrected figure found have appeared previously paper published journal <em>OncoTargets Therapy</em> featuring different authors at research institutes,...
Abstract Intermediate filaments are involved in stress-related cell mechanical properties and plasticity via the regulation of focal adhesions (FAs) actomyosin network. We investigated whether vimentin regulates endothelial cells (ECs) vascular smooth muscle (SMCs) thereby influences vasomotor tone arterial stiffness. Vimentin knockout mice (Vim −/− ) exhibited increased expression laminin, fibronectin, perlecan, collagen IV VE-cadherin as well von Willebrand factor deposition subendothelial...
To investigate the function of Aurora kinase B (AURKB) in gastric cancer (GC).Immunohistochemistry was used to assay expression AURKB 50 pairs GC and adjacent tissues, qRT-PCR conducted test normal epithelial cell lines. Two segments small interference RNAs (siRNAs) targeting were synthesized inserted into GV248 lentivirus vector. After transfected with LV-AURKB-RNAis, CCK8, wound healing, transwell flow cytometric assays performed determine influence silencing on proliferation, invasion,...
Elsholtzia bodinieri Vaniot, perennial herbs, a traditional Yunnan Chinese herbal medicine. Its whole herb can be used as commonly herbs to cure fever, headache, inflammation, indigestion etc., and its tender tip also tea in of China. However, the protective mechanism Vaniot on acute lung injury (ALI) still needs explored.ALI is characterized by respiratory which remains significant source morbidity mortality. The current study with aim determining therapeutic efficacy E....
High mobility group box 2 (HMGB2) is considered as a biomarker of poor prognosis in various cancers.This study aims to investigate the effect and mechanism HMGB2 gliomas.
Glioma accounts for the vast majority of primary brain tumors with inevitable recurrence and poor prognosis. Maternal embryonic leucine zipper kinase (MELK) is overexpressed in multiple human could activate a variety oncogenic-associated signal pathways. However, its role glioma microenvironment still largely unknown.We collected RNA sequence data clinical information gliomas from Chinese Genome Atlas (CGGA), The Cancer (TCGA), Gene Expression Omnibus (GEO) databases, investigated MELK...
Sonic hedgehog (Shh) is a crucial morphogen in the development of numerous tissues and organs, including nervous system, gastrointestinal tract lung. Recent findings suggest that Shh plays an important role thymocyte peripheral T cell function. Here we report receptors, patched smoothened, are expressed resting activated cells their expression regulated upon activation. protein also detected on surface freshly isolated cells. Although exogenous alone does not activate cells, it exhibits...
Objective This review focuses on the state-of-the-art of CXCL12/CXCR4 signaling axis in pancreatic cancer and its role tumor progression. Data sources Relevant articles published English were identified by searching Pubmed from 1997 to 2013, with keywords “CXCL12”, “CXCR4” “pancreatic cancer”. Important references selected also retrieved. Study selection Articles about relevant mechanisms selected. Results Pancreatic has been one most lethal human malignancies, median survival less than year...
Objective Numerous reports indicate a role for aberrant expression of fibroblast growth factor 19 (FGF19) in tumor development and progression, several drugs have been developed to target it. The aim this study was investigate the clinical significance FGF19 examine whether it plays any roles progression thyroid cancer. Study Design Translation research. Setting Navy General Hospital Chinese PLA, China. Subjects Methods Expression patterns protein 100 paired formalin‐fixed paraffin‐embedded...
Glioma is the most frequent type of malignant cerebral tumors. DNA damage repair genes (DDRGs) play a crucial role in development cancer. In this study, we constructed DDRGs signature and investigated potential mechanisms involved disease.RNA sequence data, microarray corresponding clinical information gliomas were downloaded from The Cancer Genome Atlas (TCGA), Chinese (CGGA), Gene Expression Omnibus (GEO). Subsequently, identified candidate by differential analysis Cox regression analysis....
Alcoholic liver disease (ALD), leading to the most common chronic diseases, is increasingly emerging as a global health problem, which intensifying need develop novel treatments. Herein, our work aimed estimate therapeutic efficacy of red rice (