A5035702714- COVID-19 and healthcare impacts
- Organ Donation and Transplantation
- Renal Transplantation Outcomes and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Renal and Vascular Pathologies
- Trauma and Emergency Care Studies
- Organ Transplantation Techniques and Outcomes
- Transplantation: Methods and Outcomes
- Respiratory Support and Mechanisms
- Organ and Tissue Transplantation Research
- Liver Disease and Transplantation
- Advances in Oncology and Radiotherapy
- Reproductive Health and Technologies
- Child and Animal Learning Development
- Prenatal Screening and Diagnostics
- Intensive Care Unit Cognitive Disorders
- Primate Behavior and Ecology
- Healthcare cost, quality, practices
- Face Recognition and Perception
- Explainable Artificial Intelligence (XAI)
- Radiation Dose and Imaging
- Artificial Intelligence in Healthcare and Education
- Autopsy Techniques and Outcomes
- Global Cancer Incidence and Screening
- Surgical site infection prevention
Addenbrooke's Hospital
2017-2024
University of Cambridge
2013-2024
Charité - Universitätsmedizin Berlin
2022
University of Birmingham
2020-2021
NIHR Birmingham Biomedical Research Centre
2021
Yorkshire Cancer Research
2021
Urology Foundation
2021
Association for Cancer Surgery
2021
AstraZeneca (Brazil)
2020
Pfizer (United Kingdom)
2020
Introduction Most potential kidney transplant donors in the UK are aged over 60 years, yet increasing donor age is associated with poorer graft survival and function. Urgent preimplantation biopsy can identify chronic injury, may aid selection of better ‘quality’ kidneys from this group. However, impact on numbers remains unproven. The PreImplantation Trial Histopathology In renal Allografts (PITHIA) study will assess whether introduction a national, 24 hours, digital histopathology service...
A growing consensus in social cognitive neuroscience holds that large portions of the primate visual brain are dedicated to processing information, i.e., those aspects stimuli usually encountered interactions such as others' facial expressions, actions and symbols. Yet, studies perception have mostly employed simple pictorial representations conspecifics. These only restricted sense they physically resemble objects with which observer would typically interact. In an equally important sense,...
Background. Preimplantation biopsy combines measurements of injury into a composite index to inform organ acceptance. The uncertainty in these remains poorly characterized, raising concerns variability may contribute inappropriate clinical decisions. Methods. We adopted metrological approach evaluate score reliability. Variability was assessed by performing repeat biopsies (n = 293) on discarded allografts 16) using 3 methods (core, punch, and wedge). Uncertainty quantified bootstrapping...
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Abstract Quality assessment in kidney transplantation involves inspection to identify negative markers of organ quality. However, there is a paucity evidence guiding surgical appraisal, and currently no differentiate important features from those that can be safely ignored. We propose method standardize derived simple rule rapidly kidneys suitable for transplantation. Donor recipient data were recorded alongside clinical outcomes prospectively maintained database. developed proforma...
Introduction Renal transplant biopsies provide insights into graft health and support decision making. The current evidence on links between biopsy scores outcomes suggests there may be numerous factors affecting scores. Here we adopt measurement science approach to investigate the sources of uncertainty in assessment suggest techniques improve its robustness. Methods Histological assessments, Remuzzi scores, processing clinical variables are obtained from 144 repeat originating 16...
Introduction Educational awareness programmes in organ donation the UK are centralised by NHS Blood and Transplant. These generically adult based, however do not target students ‘millenial’ population. Given that this cohort of adults nearing voting age likely to engage electoral system imminent future, we commenced a pilot educational programme specifically gauged towards evaluating opinions millenials regarding ethical topics transplantation. Methods Secondary schools East Anglia London...