A5084386706- Renal Transplantation Outcomes and Treatments
- Pharmacological Effects and Toxicity Studies
- Nitric Oxide and Endothelin Effects
- Endodontics and Root Canal Treatments
- Medical and Biological Sciences
- Systemic Lupus Erythematosus Research
- Dialysis and Renal Disease Management
- Advanced Glycation End Products research
- Oral and Maxillofacial Pathology
- Biochemical Acid Research Studies
- Erythropoietin and Anemia Treatment
- Cardiac Ischemia and Reperfusion
- dental development and anomalies
- Metabolism and Genetic Disorders
- Multiple Sclerosis Research Studies
- Organ Transplantation Techniques and Outcomes
- Neurological Complications and Syndromes
- Pregnancy and Medication Impact
- Liver Disease and Transplantation
- Eicosanoids and Hypertension Pharmacology
- Oral microbiology and periodontitis research
- Adenosine and Purinergic Signaling
- Diet, Metabolism, and Disease
- Neurological Disorders and Treatments
- Renal and Vascular Pathologies
University of Nis
2015-2024
Deleted Institution
2012-2023
Klinički centar Niš
2011-2020
University of Ljubljana
2019
Amrita Institute of Medical Sciences and Research Centre
2017
General University Hospital in Prague
2017
Institute of Biochemistry
1998-2016
ACTA (United States)
2014
Cardialysis (Netherlands)
2012
Inštitut Bion
2004-2009
The aim of the study was to evaluate intensity oxidative stress in brain animals chronically exposed mobile phones and potential protective effects melatonin reducing injury.Experiments were performed on Wistar rats microwave radiation during 20, 40 60 days. Four groups formed: I group (control)- treated by saline, intraperitoneally (i.p.) applied daily follow up, II (Mel)- with (2 mg kg(-1) body weight i.p.), III (MWs)- rats, IV (MWs + Mel)- MWs i.p.). produced a test phone (SAR =...
Purine nucleotide liberation and their metabolic rate of interconversion may be important in the development hypertension its renal consequences. In present study, blood triphosphate (ATP), adenosine diphosphate (ADP), monophosphate (AMP) breakdown pathway was evaluated relation to uric acid concentration xanthine dehydrogenase/xanthine oxidase (XDH/XO) patients with essential hypertension, chronic diseases on dialysis, control individuals. The pattern catabolism significantly shifted toward...
Summary The presence of diabetes mellitus leads to a decrease in life quality all domains. aim our study was evaluate the (QOL) diabetic patients and factors affecting it type 2 patients. We conducted cross-sectional that included 86 with mellitus, territory City Niš. Health-related QOL measured using short form survey (SF-36) produces an 8-scale health profile. average duration 12.76±8.08 years. best areas observed diagnosed less than 10 years ago p<0.05) younger 65 Male respondents...
The aim of our study was to compeer levels antioxidative agent -total SH groups and the finale product lipid peroxidationmalondialdehyde (MDA) in serum, glutathione (GSH) MDA nucleocortical parts lens after extracapsular extraction cataract. Patient were (38 with cataract 38 controls) matched by sex years life. Diagnosis established complete ocular examination. All results are expressed as mean ± S.D. A Student’s t-test used estimate differences between groups. level significance p<0,05....
Chronic heart failure (CHF) is a severe condition, often co-occurring with depression and anxiety, that strongly affects the quality of life (QoL) in some patients. Conversely, depressive anxiety symptoms are associated 2-3 fold increase mortality risk were shown to act independently typical factors CHF progression. The aim this study was examine impact depression, QoL on occurrence rehospitalization within one year after discharge patients.148 patients enrolled 10-center, prospective,...
Introduction. In spite of the growing number reports on study anti-nucleosome and anti-C1q antibodies, there are still controversies their significance as disease activity markers in patients with systemic lupus erythematosus (SLE) use everyday clinical practice. Objective. Our aim was to assess presence anti-dsDNA, antibodies SLE patients, well establish sensitivity, specificity, positive negative predictive value, correlation nephritis activity. Methods. The enrolled 85 aged 45.3?9.7 years...
The aim of this study was to determine oxidative stress (OS) parameters after testicular torsion/detorsion in adult rats.In experimental study, male Wistar rats were divided into four groups, each consisting seven animals: group I-one hour right torsion with subsequent orchiectomy, II-one followed by detorsion, III-unilateral right-sided orchiectomy without previous and IV-control. After 30 days, bilateral orchiectomies performed both testes unilateral single testicles. Parameters OS...
The complexation of humic acid with certain heavy metal ions (Co(II), Ni(II), Cu(II), Zn(II) and Pb(II)) was investigated. stability constants humate complexes were determined by method which is based on distribution between solution resin in the presence absence ligand, known as Schubert?s ion exchange method. Experiments performed at 25 ?C, pH 4.0 ionic strength 0.01 mol dm-3. It found that 1:1 formed acid. Obtained results constants, log ?mn, follow order Co(II) < Ni(II) Cu(II) >...
Heavy metal pollution is a serious environmental and health problem. The negative effects of heavy metals that can enter human body be reduced by the addition some supplements. In this study, lead (Pb), cadmium (Cd) copper (Cu) on hematological parameters in Wistar rats absence presence lipoic acid glutathione were analyzed. Pb, Cd Cu intoxication significantly affected treated animals. main case Pb decreased values erythrocytes, hemoglobin hematocrit (up to 30% 20% for these two metals,...
<b><i>Objectives:</i></b> To assess the degree of immunosuppressive medication adherence in kidney transplant patients (KTPs) and to determine if there is a difference rate tacrolimus (Tac), cyclosporine (CsA) sirolimus (Sir). <b><i>Subjects Methods:</i></b> From total 63 KTPs treated at Clinic Nephrology, Clinical Centre Niš, Serbia, 60 participated study by responding questionnaires. They were divided into group (n = 43) nonadherence 17)...
Cadmium is a widespread, toxic industrial pollutant. The proximal tubule of the mammalian kidney major target Cd-induced toxicity. We analyzed effects cadmium exposure on model system experimental animals, thiobarbituric acid (TBA)-reactive substance (TBARS) level, and activity xanthine oxidase (XO) catalase in rats, with without glutathione lipoic (LA). animals were classified into six groups, regarding cadmium, glutathione, LA intake. concentration TBARSs homogenate was determined by...
Rhabdomyolysis may account for about 10% of all cases acute renal failure (ARF). This study was performed to explore the protective influence proanthocyanidins from seeds grape in an experimental model myoglobinuric ARF. Rats were injected with 50% glycerol (8 mL/Kg, im) followed immediately and daily next three days by ip (20 mg/kg) or saline. After 96 h rats sacrificed kidney morphology, cortex peptidase activities, malondialdehyde (MDA) content determined. A moderate produced injection...
Background: End-stage renal disease is a state of enhanced oxidative stress (OS) and hemodialysis (HD) anemia further augment this disbalance.Anemia correction with erythropoietin (EPO) may improve status.However, there no evidence time dependent effects EPO therapy on redox status HD patients.Objective: The aim study was to evaluate whether the duration treatment affect OS parameters in uremic patients.Patients methods: 104 patients 29 healthy volunteers were included.Patients divided into...
Background. Bronchial asthma is an inflammatory disease resulting from a combination of genetic and environmental factors. Single nucleotide polymorphisms in the regulatory regions cytokine antioxidant enzyme genes may affect production activity, thus play contributory role pathogenesis.Objectives. The aim this study was to examine association manganese superoxide dismutase (MnSOD) Ala16Val, catalase (CAT) A-21T tumor necrosis factor alpha (TNF-α) G-308A with bronchial asthma.Material...