Aristide S. Hien

ORCID: 0000-0001-6649-6676
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About
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Research Areas
  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Insect Resistance and Genetics
  • Insect Pest Control Strategies
  • Parasitic Diseases Research and Treatment
  • Dengue and Mosquito Control Research
  • Viral Infections and Vectors
  • Parasites and Host Interactions
  • Pesticide Exposure and Toxicity
  • Iron Metabolism and Disorders
  • Cholinesterase and Neurodegenerative Diseases

Institut de Recherche en Sciences de la Santé
2017-2025

Centre Muraz
2017-2024

Centre National de la Recherche Scientifique et Technologique
2024

Nazi Boni University
2020-2021

Abt Associates (Nepal)
2021

Centre Hospitalier Universitaire Yalgado Ouédraogo
2020

Many studies have shown the role of agriculture in selection and spread resistance Anopheles gambiae s.l. to insecticides. However, no study has directly demonstrated presence insecticides breeding sources as a source for this resistance. It is context that we investigated pesticide residues habitats their formal involvement vector areas West Africa with intensive farming. This was carried out from June November 2013 Dano, southwest Burkina Faso conventional (CC) biological cotton (BC)...

10.1371/journal.pone.0173098 article EN cc-by PLoS ONE 2017-03-02

Pyrethroid resistance in the Anopheles vectors of malaria is driving an urgent search for new insecticides that can be used proven vector control tools such as insecticide treated nets (ITNs). Screening potential requires access to stable colonies predominant species contain major pyrethroid mechanisms circulating wild populations. Southwest Burkina Faso apparent hotspot emergence gambiae complex. We established from larval collections across this region and characterised phenotype...

10.3390/insects13030247 article EN cc-by Insects 2022-02-28

Effective tools to prevent mosquito bites are essential for malaria control. The Lehmann Funnel Entry Trap (LFET), a window screen proven effective in reducing density, was tested its large-scale impact on vector control and community acceptance. A total of 1313 traps were deployed Vallée du Kou 3 (VK3), with 12 randomly selected detailed evaluation against untrapped houses 5 (VK5). Traps placed windows doors blocked by curtains. From July October, mosquitoes collected nine days per month...

10.3390/tropicalmed10020049 article EN cc-by Tropical Medicine and Infectious Disease 2025-02-07

Background: A severe outbreak of dengue occurred in Burkina Faso 2016, with the main cases reported Ouagadougou, which highlights necessity to implement vector surveillance system. This study aims estimate risk arboviruses transmission and insecticide susceptibility status potential vectors four sites Faso. Methods: From June September house-to-house cross sectional entomological surveys were performed cities stretching along a southwest-to-northeast railway transect. The household analyzed...

10.3389/fvets.2019.00140 article EN cc-by Frontiers in Veterinary Science 2019-05-28

Abstract Background Pyrethroid resistance poses a major threat to the efficacy of insecticide-treated nets (ITNs) in Burkina Faso and throughout sub-Saharan Africa, particularly where is present at high intensity. For such areas, there are alternative ITNs available, including synergist piperonyl butoxide (PBO)-based dual active ingredient as Interceptor G2 (treated with chlorfenapyr alpha-cypermethrin). Before deploying on large scale it crucial characterize profiles primary malaria vector...

10.1186/s12936-021-03936-3 article EN cc-by Malaria Journal 2021-10-18

Abstract Background National Malaria Programmes (NMPs) monitor the durability of insecticide-treated nets (ITNs) to inform procurement and replacement decisions. This is crucial for new dual active ingredients (AI) ITNs, which less data available. Pyrethroid-only ITN (Interceptor ® ) AI (Interceptor® G2, PermaNet 3.0) ITNs were assessed across three health districts over 36 months in southern Burkina Faso estimate median survival, insecticidal efficacy, identify factors contributing field...

10.1186/s12936-024-04989-w article EN cc-by Malaria Journal 2024-06-04

In West Africa, Aedes aegypti remains the major vector of dengue virus. Since 2013, fever has been reemerging in Burkina Faso with annual outbreaks, thus becoming a public health problem. Its control relies on control, which is unfortunately facing problem insecticide resistance. At time this study, although data phenotypic resistance were available, information related to metabolic populations from remained very scarce. Here, we assessed and Ae. sampled two main urban areas (Ouagadougou...

10.3390/tropicalmed5020084 article EN cc-by Tropical Medicine and Infectious Disease 2020-05-27

Abstract Background The rapid spread of insecticide resistance in malaria vectors and the rebound cases observed recently some endemic areas underscore urgent need to evaluate deploy new effective control interventions. A randomized trial (RCT) was conducted with aim investigate benefit deploying complementary strategies, including indoor residual spraying (IRS) pirimiphos-methyl addition long-lasting insecticidal nets (LLINs) Diébougou, southwest Burkina Faso. Methods We measured...

10.1186/s13071-020-04563-8 article EN cc-by Parasites & Vectors 2021-01-18

Abstract Background This study reports an updated description on malaria vector diversity, behaviour, insecticide resistance and transmission in the Diébougou Dano peri-urban areas, Burkina Faso. Methods Mosquitoes were caught monthly using CDC light traps pyrethrum spray catches. identified morphological taxonomic keys. PCR techniques used to identify species of Anopheles gambiae complex mechanisms a subset vectors. The Plasmodium sporozoite infection status origins blood meals female...

10.1186/s12936-020-03554-5 article EN cc-by Malaria Journal 2021-01-25

Malaria, one of the world's greatest public health challenges, is an endemic disease with stable transmission in Togo. Combating malaria requires effective vector control. This study provides temporal data on insecticide resistance status major Anopheles gambiae sensu lato (s.l.) from Togo.Two to 5 days old females An. s.l., originating three localities (Baguida, Kovié, Kolokopé) were subjected insecticide-impregnated papers during 3 years (2012, 2013, 2016) as follows: organochlorides (4%...

10.1186/s12936-019-2813-z article EN cc-by Malaria Journal 2019-05-22

<ns4:p><ns4:bold>Background:</ns4:bold> Malaria cases in some areas could be attributed to vector resistant the insecticide. World Health Organization recommended insecticides for control are limited number. It is essential find rotational partners existing Indoor Residual Spraying (IRS) products. VECTRON<ns4:sup>™</ns4:sup> T500 a novel insecticide with broflanilide as active ingredient. has mode of action on mosquitoes completely different usually used. The aim this study was determine...

10.12688/gatesopenres.13578.2 preprint EN cc-by Gates Open Research 2022-07-25

Entomological surveillance of lymphatic filariasis and malaria infections play an important role in the decision-making national programs to control, or eliminate these both diseases. In areas where diseases prevalence is low, a large number mosquitoes need be sampled determine vectors infection rate. To do this, efficient mosquito collection methods must used. This study part this framework, assess appropriate for xenomonitoring coexistence context with Burkina Faso. Mosquito collections...

10.1371/journal.pntd.0012021 article EN PLoS neglected tropical diseases 2024-03-29

A novel strategy applying an organophosphate-based insecticide paint on doors and windows in combination with long-lasting insecticide-treated nets (LLINs) was tested for the control of pyrethroid-resistant malaria vectors a village setting Vallée du Kou, rice-growing area west Burkina Faso. Insecticide Paint Inesfly 5A IGR™, comprised two organophosphates insect growth regulator, applied to pyrethroid-treated LLINs. The killing effect monitored 5 months by early morning collections...

10.1186/s12936-018-2273-x article EN cc-by Malaria Journal 2018-04-02

Twenty years after the latest publications performed on parasitological indices of malaria transmission in northwest second city Burkina Faso, it was important to update epidemiological profile children under age 15 years. The objective this study determine and compare parameters by season, area, two zones (rice savanna) Bobo-Dioulasso, Faso. Overall, results showed that there no significant difference within fifteen between rice site savannah whatever season (<mml:math...

10.1155/2017/1507829 article EN cc-by Journal of Tropical Medicine 2017-01-01

Introduction: Lymphatic filariasis (LF) and malaria are two vector-borne diseases which parasites can simultaneously infect human or mosquito. In Burkina Faso, studies mainly focused on the control of these independently. Hence, there is a lack information their co-transmission to both vector. The present study aimed at providing baseline data from endemic areas in Faso towards successful integrated management diseases. Methods: was carried out six sites distributed East, Center-East...

10.4236/ae.2021.94014 article EN Advances in Entomology 2021-01-01

Abstract Indoor residual spraying (IRS) was applied in addition to the use of long-lasting insecticidal nets South West Burkina Faso, where Anopheles gambiae s.l. major malaria vector resistant pyrethroids. This study designed evaluate efficacy and life bendiocarb (active ingredient) used for on different wall surfaces (mud cement). Cone bioassays were done monthly with susceptible An. ‘Kisumu’ strain local wild populations determine duration which insecticide effective killing mosquitoes....

10.1093/jme/tjaa240 article EN Journal of Medical Entomology 2020-11-09

The efficacy of insecticide-treated nets (ITNs) is increasingly compromised by the prevalence malaria vectors resistant to pyrethroids. In response this issue, a new generation ITNs has been developed that incorporate synergistic components, such as piperonyl butoxide (PBO). purpose study provide entomological evidence for PBO-based ITN brand at village level, serving basis decision-making before large-scale net deployment. During high transmission period, were distributed in each group and...

10.4236/ae.2024.123018 article EN Advances in Entomology 2024-01-01

<title>Abstract</title> WHO Global Malaria Programme recommends the development of an appropriate and comprehensive response to insecticide resistance based on use multiple insecticides with different modes action in rotations mixtures. It is, therefore, judicious prevent rapid spread by developing evaluating new formulations containing a long residual effect. A IRS formulation VECTRON™ T500 has been developed Mitsui Chemicals Crop &amp; Life Solutions, Inc. broflanilide (applied at rate 100...

10.21203/rs.3.rs-4913757/v1 preprint EN Research Square (Research Square) 2024-09-12

Abstract Background A quasi-experimental comparative trial will be designed in Burkina Faso. The study compare the use and preferences for two groups types of insecticide-treated nets textile: polyester-based polyethylene-based, according to their selected health districts. These districts three eco-climate zones (Sahelian, dry savannah wet savannah) country. findings inform decisions on future net procurements national malaria control programme 2025. Methods Quantitative surveys qualitative...

10.1186/s12936-024-05105-8 article EN cc-by Malaria Journal 2024-09-12

Abstract Background Insecticide-treated nets (ITNs) are the most commonly deployed tools for controlling malaria transmission in sub-Saharan Africa. However, some reports associate multiple alternative uses of with poor disposal practices, prompting this study to assess existing and practices old ITNs Burkina Faso after four universal distribution campaigns. Methods A quantitative survey combined qualitative data collection was used describe households from selected sites three climatic...

10.1186/s12936-024-05181-w article EN cc-by Malaria Journal 2024-11-20

Abstract Background The WHO Global Malaria Programme advocates for a comprehensive, strategic approach to managing insecticide resistance, highlighting the importance of using multiple insecticides with different modes action through rotations and combinations. To slow spread it is essential develop evaluate new formulations that feature unique extended residual effects. Addressing this need, Mitsui Chemicals Crop &amp; Life Solutions, Inc., developed VECTRON™ T500, indoor spraying (IRS)...

10.1186/s13071-024-06577-y article EN cc-by Parasites & Vectors 2024-11-23

In 2016, an entomological study was carried out in a railway transect between Banfora and Ouagadougou, Burkina Faso. The objective to assess the risk factors of arbovirus outbreaks, including vector-borne infection status within representative regions country. Aedes aegypti mosquitoes were collected at larval stage from their natural rearing habitats four sites when estimating main index, then reared until adult kept RNAlater for detection RNA. laboratory, mosquito samples tested dengue...

10.3389/fitd.2022.920224 article EN cc-by Frontiers in Tropical Diseases 2022-09-14

Context: The vector control is essential in malaria prevention strategies several endemic countries Africa including Burkina Faso. high transmission of occurs during the period abundance (August to October) Therefore, a strategy based on use indoor residual spraying targeting this should provide effective protection against malaria. This study aimed evaluate effect bendiocarb applied entomological parameters pyrethroid resistance area southwestern, Methods: CDC light trap and early morning...

10.4236/ae.2020.84012 article EN Advances in Entomology 2020-01-01

Abstract: In 2016, we conducted an entomological survey in a railway transect between Banfora and Ouagadougou, Burkina Faso. The aim was to evaluate the risk factors for arbovirus epidemics, including vector infection status, areas representative of country. Aedes aegypti mosquitoes were collected at larval stage from four study sites reared until adult kept RNAlater detection RNA. laboratory, mosquito specimens screened dengue virus (DENV) chikungunya (CHIKV) using one step real-time...

10.20944/preprints202108.0077.v1 preprint EN 2021-08-03

Abstract Background Entomological surveillance of lymphatic filariasis (LF) and malaria infections play an important role in the decision-making national programs, to control or eliminate these both diseases. In order corroborate human population, sampling large numbers mosquitoes is necessary. To overcome this challenge, study was design assess efficiency four mosquito collection methods for monitoring LF population. Methodology/Principle Findings Mosquito collections were performed between...

10.1101/2022.04.26.489492 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2022-04-27
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