A5003752106- Mosquito-borne diseases and control
- Malaria Research and Control
- Insect Pest Control Strategies
- Insect Resistance and Genetics
- Essential Oils and Antimicrobial Activity
- Viral Infections and Vectors
- Insect and Pesticide Research
- CRISPR and Genetic Engineering
- Parasites and Host Interactions
- Insect symbiosis and bacterial influences
- Agricultural pest management studies
- Entomopathogenic Microorganisms in Pest Control
- Moringa oleifera research and applications
- Agriculture and Rural Development Research
- Dengue and Mosquito Control Research
- Insect Utilization and Effects
- Cholinesterase and Neurodegenerative Diseases
- Parasite Biology and Host Interactions
- Forensic Entomology and Diptera Studies
- Yersinia bacterium, plague, ectoparasites research
- Phytoplasmas and Hemiptera pathogens
- Iron Metabolism and Disorders
- Insect-Plant Interactions and Control
- African Botany and Ecology Studies
- Zoonotic diseases and public health
Institut de Recherche en Sciences de la Santé
2013-2024
Centre Muraz
2014-2024
Nazi Boni University
2017-2024
Malaria control programs are being jeopardized by the spread of insecticide resistance in mosquito vector populations. The situation Burkina Faso is emblematic with Anopheles gambiae populations showing high levels to most available compounds. Although frequency target-site mutations including knockdown (kdr) and insensitive acetylcholinesterase (Ace-1R) alleles has been regularly monitored area, it not known whether detoxifying enzymes contribute diversity phenotypes observed field. Here,...
Many studies have shown the role of agriculture in selection and spread resistance Anopheles gambiae s.l. to insecticides. However, no study has directly demonstrated presence insecticides breeding sources as a source for this resistance. It is context that we investigated pesticide residues habitats their formal involvement vector areas West Africa with intensive farming. This was carried out from June November 2013 Dano, southwest Burkina Faso conventional (CC) biological cotton (BC)...
This study reports on the distribution of pyrethroid and DDT resistance L1014F knockdown (kdr) mutation in Anopheles gambiae s.l. populations from 21 localities three different climatic zones Burkina Faso August to October 2006. The susceptibility these was assessed by bioassay using (4%), permethrin (1%) deltamethrin (0.05%). Anophelesgambiae were resistant both Sudanian regions but susceptible central sahelian areas at all sites except Orodara, although mortality values some close...
In the city of Bobo-Dioulasso in Burkina Faso, Anopheles arabiensis has superseded gambiae s.s. as major malaria vector and larvae are found highly polluted habitats normally considered unsuitable for mosquitoes. Here we show that An. s.l. adults emerging from a site centre (Dioulassoba) have high prevalence DDT resistance (percentage mortality after exposure to diagnostic dose=65.8% dry season 70.4% rainy season, respectively). An investigation into mechanisms responsible an unexpectedly...
Malaria vectors have acquired widespread resistance throughout sub-Saharan Africa to many of the currently used insecticides. Hence, there is an urgent need develop alternative strategies including development new insecticides for effective management insecticide resistance. To maintain progress against malaria, it necessary identify other residual mosquito nets. In present WHOPES phase II analogue study, utility chlorfenapyr, a pyrrole class mixed with alpha-cypermethrin on long-lasting bed...
An entomological survey was carried out at 15 sites dispersed throughout the three eco-climatic regions of Burkina Faso (West Africa) in order to assess current distribution and frequency mutations that confer resistance insecticides An. gambiae s.l. populations country. Both knockdown (kdr) mutation variants (L1014F L1014S), pyrethroid insecticides, were identified concomitant with ace-1 G119S confirming presence multiple mechanisms complex Faso. Compared last survey, L1014F kdr appears...
Abstract Every year, malaria kills approximately 405,000 people in Sub-Saharan Africa, most of them children under the age five years. In many countries, progress control has been threatened by rapid spread resistance to antimalarial drugs and insecticides. Novel genetic mosquito approaches could play an important role future integrated strategies. July 2019, Target Malaria consortium proceeded with first release hemizygous genetically-modified (GM) sterile non-transgenic sibling males...
Abstract Background Historical studies have indicated that An. gambiae s.s. is the predominant malaria vector species in Bobo-Dioulasso second biggest city of Burkina Faso (West Africa). However, over last decade, arabiensis appears to be replacing as most prevalent this urban setting. To investigate transition more detail present study aims provide an update on composition Bobo-Dioulasso, and also Plasmodium infection rates susceptibility insecticides local s.l. population. Methods An...
<ns3:p>Background <ns3:italic>Metarhizium</ns3:italic> spp. based mosquito control products are among the most investigated and could potentially serve as promising complements to chemical insecticides. However, limited knowledge exists on implementation of this biocontrol tool in conjunction with primary insecticide-based strategies achieve synergy. Methods In laboratory bioassays, we combined 10<ns3:sup>7</ns3:sup> conidia/ml native <ns3:italic>Metarhizium pingshaense</ns3:italic> strains...
Adult females An. gambiae were exposed in 3 min cone test to treated nets with PPF before or after they blood fed. The effects of on ovaries development, oviposition and eggs hatching assessed. Both unfed fed mosquitoes exhibited nearly complete inhibition fecundity (70-100%) fertility (90-100%). After have been once PPF, the sterilizing effect their was observed over consecutive meals suggesting that might an irreversible effect. Observation under microscope revealed failed develop even...
Background: A severe outbreak of dengue occurred in Burkina Faso 2016, with the main cases reported Ouagadougou, which highlights necessity to implement vector surveillance system. This study aims estimate risk arboviruses transmission and insecticide susceptibility status potential vectors four sites Faso. Methods: From June September house-to-house cross sectional entomological surveys were performed cities stretching along a southwest-to-northeast railway transect. The household analyzed...
In West Africa, Aedes aegypti remains the major vector of dengue virus. Since 2013, fever has been reemerging in Burkina Faso with annual outbreaks, thus becoming a public health problem. Its control relies on control, which is unfortunately facing problem insecticide resistance. At time this study, although data phenotypic resistance were available, information related to metabolic populations from remained very scarce. Here, we assessed and Ae. sampled two main urban areas (Ouagadougou...
Background In view of widespread pyrethroid resistance in malaria vectors Africa, two long-lasting insecticidal nets (LLINs) incorporated with a synergist, piperonyl butoxide (PBO), DawaPlus 3.0 (deltamethrin + PBO the roof panel; deltamethrin alone side panels) and 4.0 all panels), were evaluated an experimental hut trial rice growing irrigated area Burkina Faso. Efficacy was tested against free-flying vector, Anopheles gambiae s.l., high involving L1014F kdr CYP6P3P450 mechanisms....
Abstract Background This study reports an updated description on malaria vector diversity, behaviour, insecticide resistance and transmission in the Diébougou Dano peri-urban areas, Burkina Faso. Methods Mosquitoes were caught monthly using CDC light traps pyrethrum spray catches. identified morphological taxonomic keys. PCR techniques used to identify species of Anopheles gambiae complex mechanisms a subset vectors. The Plasmodium sporozoite infection status origins blood meals female...
Despite the implementation of different strategies to fight against malaria in Burkina Faso since 2005, it remains today leading cause hospitalization and death. Adapting interventions spatial temporal distribution could help reduce this burden. This study aims determine structure stability hotspots Faso, with objective adapting at small geographical scales. Data on cases from 2013 2020 were acquired municipalities level. Municipality-wise endemicity levels mapped through information system...
Mosquitoes genus Aedes are the most important arthropod disease vector. Dengue Virus (DENV) and Chikungunya (CHIKV) main arboviruses distributed in world. Based on entomo-virological surveillance, appropriating public health strategies can be addressed to contain cases control outbreaks. This study aims show potential performance of two new molecular methods for detecting DENV serotypes CHIKV mosquitoes. were collected urban areas sylvatic between July August 2023, screened using multiplex...
Malaria vectors have evolved resistance to almost all WHO-recommended insecticides, which compromises vector control. This study aimed evaluate the insecticidal activity of four doses fixed oils from Jatropha curcas and Ricinus communis on Anopheles gambiae in western Burkina Faso. Biological tests susceptibility oil were carried out two populations An. complex August October 2022 using WHO standard protocol. The synergistic or antagonistic effects extracts’ combinations evaluated by...
Novel approaches to area-wide control of vector species offer promise as additional tools in the fight against vectored diseases. Evaluation transgenic insect strains aimed at field population disease-endemic countries may involve international partnerships and should be done a stepwise approach, starting with studies containment facilities. The preparations both new-build renovated facilities are described, including working local national regulations regarding land use, construction,...