A5061736630- Mosquito-borne diseases and control
- Malaria Research and Control
- Insect Resistance and Genetics
- Insect Pest Control Strategies
- Viral Infections and Vectors
- Insect symbiosis and bacterial influences
- Invertebrate Immune Response Mechanisms
- Trypanosoma species research and implications
- Zoonotic diseases and public health
- Neurobiology and Insect Physiology Research
- Parasite Biology and Host Interactions
- Dengue and Mosquito Control Research
- Identification and Quantification in Food
- African Botany and Ecology Studies
- Genomics and Phylogenetic Studies
- Yersinia bacterium, plague, ectoparasites research
- Genetic diversity and population structure
- Helminth infection and control
- Research on Leishmaniasis Studies
- Animal Behavior and Reproduction
- Parasitic Diseases Research and Treatment
- Dermatological diseases and infestations
- Reproductive tract infections research
- Species Distribution and Climate Change
- Insect Utilization and Effects
Université de Montpellier
2017-2024
Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle
2014-2024
Institut de Recherche pour le Développement
2014-2024
Centre National de la Recherche Scientifique
2014-2024
Centre International de Recherches Médicales de Franceville
2019-2024
Agropolis International
2008-2023
Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale
2003-2017
Institut de Recherche pour le Développement
2002-2015
Universidad de Guadalajara
2009
Autonomous University of Yucatán
2009
Significance Transmission of malarial parasites occurs via the bites Anopheles mosquitoes, whose blood-feeding behavior modulates risk infection. In many malaria endemic regions, eradication strategies rely on reducing transmission by targeting nocturnal with insecticidal nets. However, a proportion mosquitoes may naturally feed when humans are not protected nets, setting ceiling to efficacy massive net-based interventions. Bangui, Central African Republic, 20 30% daily exposure indoor...
Background Anthropogenic habitat disturbance is a prime cause in the current trend of Earth's reduction biodiversity. Here we show that human footprint on Central African rainforest, which resulting deforestation and growth densely populated urban agglomerates, associated to ecological divergence cryptic speciation leading adaptive radiation within major malaria mosquito Anopheles gambiae. Methodology/Principal Findings In southern Cameroon, frequency two molecular forms–M S–among...
Abstract Background Limitations in the ability of organisms to tolerate environmental stressors affect their fundamental ecological niche and constrain distribution specific habitats. Evolution tolerance, therefore, can engender dynamics. Forest populations afro-tropical malaria mosquito Anopheles gambiae have been shown adapt historically unsuitable larval habitats polluted with decaying organic matter that are found densely populated urban agglomerates Cameroon. This process has resulted...
Abstract Complexes of closely related species provide key insights into the rapid and independent evolution adaptive traits. Here, we described studied Anopheles fontenillei sp.n., a new in gambiae complex that recently discovered forested areas Gabon, Central Africa. Our analysis placed taxon phylogenetic tree An . complex, revealing important introgression events with other members complex. Particularly, detected recent introgression, coluzzii , genes directly involved vectorial capacity....
Anopheles funestus is a major vector of malaria in Africa. It belongs to group sibling species that can be identified morphologically only at certain stages their development. A diagnostic polymerase chain reaction (PCR)-based tool made it possible differentiate five the group. The assay seems applicable over all distribution area for four these species: An. funestus, leesoni, parensis, and vaneedenip. fifth species, rivulorum, second most abundant mistaken its adult stage funestus....
Summary During extensive sampling in Burkina Faso and other African countries, the Leu‐Phe mutation producing kdr pyrethroid resistance phenotype was reported both Anopheles gambiae ss A. arabiensis . This widely distributed at high frequency molecular S form of while it has been observed a very low M Faso. While is inherited through an introgression from form, its occurrence new independent event Three nucleotides upstream intron differentiated these specific were associated with Ecological...
This study reports on the distribution of pyrethroid and DDT resistance L1014F knockdown (kdr) mutation in Anopheles gambiae s.l. populations from 21 localities three different climatic zones Burkina Faso August to October 2006. The susceptibility these was assessed by bioassay using (4%), permethrin (1%) deltamethrin (0.05%). Anophelesgambiae were resistant both Sudanian regions but susceptible central sahelian areas at all sites except Orodara, although mortality values some close...
Understanding how divergent selection generates adaptive phenotypic and population diversification provides a mechanistic explanation of speciation in recently separated species pairs. Towards this goal, we sought ecological gradients divergence between the cryptic malaria vectors Anopheles coluzzii An. gambiae then looked for physiological trait that may underlie such divergence. Using large set occurrence records eco-geographic information, built distribution model to predict predominance...
Resistance of Anopheles gambiae to organophosphate and carbamate insecticides was first reported in Côte d'Ivoire, West Africa. Subsequent studies revealed that it resulted from a single point mutation the oxyanion hole acetycholinesterase enzyme (ace-1(R) mutation). We investigated distribution prevalence ace-1(R) An. s.l. populations seven locations south-western Burkina Faso. The found both M S molecular forms s.s., but absent arabiensis. Its frequency ranged 0.25 0.5 form 0.04 0.13 form,...
Summary Objective To investigate through countrywide sampling at 20 localities across the three different agro‐climatic zones of Burkina Faso, distribution acetylcholinesterase insensitive mutation ace‐1 R , which confers resistance to organophosphates (OP) and carbamates (CM) insecticides in An. gambiae s.l. Methods Adult mosquitoes were collected by indoor aerosol spraying from August October 2006. Specimens identified species polymerase chain reaction (PCR) assay characterized for ace ‐ 1...
During the last decade, endosymbiont bacterium Wolbachia has emerged as a biological tool for vector disease control. However, long time, it was believed that absent in natural populations of Anopheles. The recent discovery species within Anopheles gambiae complex host conditions opened new opportunities malaria control research Africa. Here, we investigated prevalence and diversity infection 25 African Gabon (Central Africa). Our results revealed presence 16 these species, including major...
Abstract We look at the link between climate change and vector-borne diseases in low- middle-income countries Africa. The large endemicity escalating threat of such as malaria arboviral diseases, intensified by change, disproportionately affects vulnerable communities globally. highlight urgency prioritizing research development, advocating for robust scientific inquiry to promote adaptation strategies, vital role that next generation African leaders will play addressing these challenges....
A sodium channel 'kdr'-type mutation was identified in the M form of Anopheles gambiae from Burkina Faso tropical savannah area belt. The molecular An. is found at high frequencies flooded rice cultivation Kou Valley, where insecticide selection pressure limited. spread population an ongoing process, as it increased a frequency 0.006 1999 to 0.02 2000. S occurs sympatry our study village, with relatively low frequency. common 'kdr' previously detected this form, and has probably invaded...
The M and S molecular forms of Anopheles gambiae sensu stricto Giles are thought to be reproductively isolated through premating barriers. However, the exact mechanisms recognition conspecific partners unknown. Because mating in An. occurs swarms, one might expect swarming behavior between different that this probably reduces risk contact males females areas where they sympatric. We report occurrence four mixed containing forms, out a total 26 swarms sampled Soumousso, typical savannah...
Rapid demographic growth in Douala city, Cameroon, has resulted profound ecological and environmental changes. Although changes can affect anopheline mosquito breeding sites, there is a lack of understanding about the epidemiological impact that such might have on vector ecology malaria transmission. A 12-month entomological study was conducted highly populated district called Ndogpassi. Adult mosquitoes were collected using two methods: 1) human landing catches (HLC); 2) Centers for Disease...
The involvement of members the Anopheles gambiae complex Giles and An. funestus nili Theobald groups in transmission Plasmodium falciparum was recently investigated villages Gbatta Kpéhiri, which lie, respectively, forest areas west south Côte d’Ivoire.Adult female mosquitoes were collected, using human landing catches, inside outside dwellings. After identification dissection, heads thoraces all anopheline tested, an ELISA, for circumsporozoite protein (CSP). All collected identified to...
Abstract Explaining how and why reproductive isolation evolves determining which forms of have the largest impact on process population divergence are major goals in study speciation. By studying recent adaptive radiations incompletely isolated taxa, it is possible to identify barriers involved at early before other confounding emerge after speciation complete. Sibling species Anopheles gambiae complex offer opportunities provide insights into mechanisms. Here, we studied patterns among...
Background Since its first record in urban areas of Central-Africa the 2000s, invasive mosquito, Aedes albopictus , has spread throughout region, including remote villages forested areas, causing outbreaks -borne diseases, such as dengue and chikungunya. Such invasion might enhance Ae . interactions with wild animals forest ecosystems favor spillover zoonotic arboviruses to humans. The aim this study was monitor wildlife reserve La Lopé National Park (Gabon), evaluate magnitude rainforest...
In Africa, vector-borne diseases are a major public health issue, especially in cities. Urban greening is increasingly considered to promote inhabitants’ well-being. However, the impact of urban green spaces on vector risk remains poorly investigated, particularly forests poor hygienic conditions. Therefore, using larval sampling and human landing catches, this study investigated mosquito diversity forest patch its inhabited surroundings Libreville, Gabon, central Africa. Among 104 water...
Abstract. Distinction between members of the Anopheles nili group mosquitoes (Diptera: Culicidae), including major malaria vectors in riverside villages tropical Africa, has been based mainly on doubtful morphological characters. Sequence variations ribosomal DNA second internal transcribed spacer (ITS2) and D3 28S region forms revealed four genetic patterns corresponding to typical An. (Theobald), carnevalei Brunhes et al ., somalicus Rivola & Holstein newly identified variant...
Journal Article Description and Bionomics of Anopheles (Cellia) ovengensis (Diptera: Culicidae), a New Malaria Vector Species the nili Group from South Cameroon Get access H. P. Awono-ambene, Awono-ambene 1Medical Research Centre, Institute Medical Medicinal Plant studies, P.O. Box 1457 MINREST, Yaoundé, Cameroon.2Laboratoire IRD de recherche sur le paludisme, Organisation Coordination pour la lutte contre les Endémies en Afrique Centrale, 288 Cameroon. Search for other works by this author...
Summary Triatoma infestans is the main vector of Chagas disease and target control programmes in Southern Cone countries. So far Bolivia only country where true T. wild foci are documented. The dispersal ability for was studied at microgeographical scale Bolivian Andes, to assess possibility populations actively recolonize insecticide‐treated villages. Nine microsatellite loci were used detect extent gene flow between neighbouring collecting sites. detection restricted close but distinct...