A5085806972- Mosquito-borne diseases and control
- Malaria Research and Control
- Insect Pest Control Strategies
- Parasite Biology and Host Interactions
- Insect symbiosis and bacterial influences
- Toxin Mechanisms and Immunotoxins
- Insect Resistance and Genetics
- Pharmacological Effects of Natural Compounds
- Natural product bioactivities and synthesis
- Invertebrate Immune Response Mechanisms
- Insect and Arachnid Ecology and Behavior
- Neurobiology and Insect Physiology Research
- Insect and Pesticide Research
- Vector-borne infectious diseases
- Insect Utilization and Effects
- Plant Parasitism and Resistance
- Parasites and Host Interactions
- Zoonotic diseases and public health
- Helminth infection and control
- Listeria monocytogenes in Food Safety
- Diffusion and Search Dynamics
- Bacterial biofilms and quorum sensing
- Microbial Metabolism and Applications
- Food Safety and Hygiene
- Bird parasitology and diseases
Institut de Recherche en Sciences de la Santé
2015-2025
AFRICSanté
2025
Centre international de recherche-développement sur l'elevage en zone subhumide
2020-2024
Agropolis International
2015-2024
Centre National de la Recherche Scientifique et Technologique
2024
Centre National pour la Recherche Scientifique et Technique (CNRST)
2024
Institut de Recherche pour le Développement
2021-2024
Université de Montpellier
2021-2024
Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle
2015-2024
Centre National de la Recherche Scientifique
2021-2024
Host age variation is a striking source of heterogeneity that can shape the evolution and transmission dynamic pathogens. Compared with vertebrate systems, our understanding impact host on invertebrate–pathogen interactions remains limited. We examined influence mosquito key life-history traits driving human malaria transmission. Females Anopheles coluzzii , major vector, belonging to three classes (4-, 8- 12-day-old), were experimentally infected Plasmodium falciparum field isolates. Our...
The ecological context in which mosquitoes and malaria parasites interact has received little attention, compared to the genetic molecular aspects of transmission. Plant nectar fruits are important for nutritional ecology vectors, but how natural diversity plant-derived sugar sources affects mosquito competence is unclear. To test this, we infected Anopheles coluzzi, an African vector, with sympatric field isolates Plasmodium falciparum, using direct membrane feeding assays. Through a series...
The success of current control tools in combatting malaria vectors is well established. However, sustained residual transmission Plasmodium parasites persists. Mass drug administration (MDA) to humans the endectocide ivermectin for vector receiving increasing attention. feeding upon animals escape this promising approach. Zoophagy mosquitoes sustains both population and endemic vector-borne pathogens. Therefore, only a strategy that will combine MDAs targeted at their peridomestic could be...
Malaria control demands the development of a wide range complementary strategies. We describe properties naturally occurring, non-genetically modified symbiotic bacterium,
Background Twenty-seven villages were selected in southwest Burkina Faso to implement new vector control strategies addition long lasting insecticidal nets (LLINs) through a Randomized Controlled Trial (RCT). We conducted entomological surveys the during dry cold season (January 2017), hot (March 2017) and rainy (June describe malaria vectors bionomics, insecticide resistance transmission prior this trial. Methods carried out hourly catches (from 17:00 09:00) inside outside 4 houses each...
In the fight against malaria, transmission blocking interventions (TBIs) such as vaccines or drugs, are promising approaches to complement conventional tools. They aim prevent infection of vectors and thereby reduce subsequent exposure a human population infectious mosquitoes. The effectiveness these has been shown depend on initial intensity in mosquitoes, often measured mean number oocysts resulting from an blood meal absence intervention. mosquitoes exposed high infection, current TBI...
Background and Aims: Food contamination is often linked to diverse factors such as poor food preservation, culinary techniques, the handling of products during marketing. These could facilitate spread bacteria which are among primary causes borne infections in both developing industrialized countries adding public health burden. This study aims highlight epidemiology Extended-Spectrum β-Lactamase (ESBL)-producing Salmonella strains lettuce charcuterie well investigate sales practice that aid...
Abstract Establishing how plants contribute food and refuge to insects can be challenging for small species that are difficult observe in their natural habitat, such as disease vectoring mosquitoes. Currently indirect methods of plant-host identification rely on DNA sequencing ingested plant material but often unsuccessful feed primarily sugars or have little contact with cells. Here we developed an innovative approach determine species-specific phytophagy by detecting taxon-specific...
Previous studies have shown that Plasmodium parasites can manipulate mosquito feeding behaviours such as motivation and avidity to feed on vertebrate hosts, in ways increase the probability of parasite transmission. These studies, however, been mainly carried out non-natural and/or laboratory based model systems hence may not reflect what occurs field. We now need move closer natural setting, if we are fully capture ecological evolutionary consequences these parasite-induced behavioral...
The spread of insecticide resistance in Anopheles mosquitoes and drug Plasmodium parasites is contributing to a global resurgence malaria, making the generation control tools that can overcome these roadblocks an urgent public health priority. We recently showed transmission falciparum be efficiently blocked when exposing gambiae females antimalarials deposited on treated surface, with no negative consequences major components mosquito fitness. Here, we demonstrate this approach hurdles...
Abstract Whether malaria parasites can manipulate mosquito host choice in ways that enhance parasite transmission toward suitable hosts and/or reduce attraction to unsuitable (i.e. specific manipulation) is unknown. To address this question, we experimentally infected three species of vectors with wild isolates the human Plasmodium falciparum , and examined effects immature mature infections on behavioural responses combinations calf odour, odour outdoor air using a dual-port olfactometer....
Abstract Despite its epidemiological importance, the time Plasmodium parasites take to achieve development in vector mosquito (the extrinsic incubation period, EIP) remains poorly characterized. A novel non-destructive assay designed estimate EIP single mosquitoes, and more broadly study – Anopheles vectors interactions, is presented. The uses small pieces of cotton wool soaked sugar solution collect malaria sporozoites from individual mosquitoes during feeding monitor infection status over...
Besides feeding on blood, females of the malaria vector Anopheles gambiae sensu lato readily feed natural sources plant sugars. The impact toxic secondary phytochemicals contained in plant-derived sugars mosquito physiology and development Plasmodium parasites remains elusive. focus this study was to explore influence alkaloid ricinine, found nectar castor bean Ricinus communis, ability mosquitoes transmit falciparum.Females its sibling species coluzzii were exposed ricinine through sugar...
Abstract Background The rapid spread of insecticide resistance in malaria vectors and the rebound cases observed recently some endemic areas underscore urgent need to evaluate deploy new effective control interventions. A randomized trial (RCT) was conducted with aim investigate benefit deploying complementary strategies, including indoor residual spraying (IRS) pirimiphos-methyl addition long-lasting insecticidal nets (LLINs) Diébougou, southwest Burkina Faso. Methods We measured...
Abstract Anopheles gambiae and coluzzii mosquitoes, two major malaria vectors in sub‐Saharan Africa, exhibit selectivity among plant species as potential food sources. However, it remains unclear if their preference aligns with optimal nutrient intake survival. Following an extensive screening of the effects 31 on An. Burkina Faso, we selected three for contrasting mosquito survival, namely Ixora coccinea , Caesalpinia pulcherrima Combretum indicum . We assessed sugar content these plants...
Abstract Anopheles mosquitoes mate at sunset in aerial swarms. The development of mating-based methods for effective malaria vector control requires a good knowledge the flight behaviour species mating However, process how swarms are formed and maintained remains poorly understood. Here, we characterized three-dimensional spatial temporal kinematics coluzzii males swarming above ground marker. We observed that location, shape volume were highly stereotypic, consistent over duration,...
Malaria mosquitoes mate in swarms, but how these swarms are formed and maintained remains poorly understood. We characterized three-dimensional spatial-temporal flight kinematics of Anopheles coluzzii males swarming at sunset above a ground marker. The location, shape volume were highly stereotypic, consistent over the complete duration. Swarms have an elliptical cone shape; mean varies spatially within swarm, remain rather throughout Using sensory system-informed model, we show that use...
Abstract Background The direct membrane feeding assay (DMFA), whereby gametocyte-infected blood is collected from human donors and which mosquitoes feed through a membrane, proving essential for assessing parameters influencing Plasmodium transmission potential in endemic countries. success of DMFAs closely tied to gametocyte density the blood, with relatively high gametocytaemia ensuring optimal infection levels mosquitoes. As intensity declines control efforts, occurrence asymptomatic...
Abstract Background Staphylococcus aureus (S. aureus) is one of the most widespread bacterial pathogens in animals and humans, its role as an important causative agent food poisoning well-documented. The aim this study was to highlight characterize resistance patterns methicillin-resistant S. (MRSA) charcuterie products sold selected supermarkets (SM) Bobo-Dioulasso, Burkina Faso. Methods In study, 72 samples including ham (n = 19), merguez 22), sausage 15) minced meat 16) were collected...
Whether the malaria parasite Plasmodium falciparum can manipulate mosquito host choice in ways that enhance transmission toward humans is unknown. We assessed influence of P. on blood-feeding behaviour three its major vectors (Anopheles coluzzii, An. gambiae and arabiensis) Burkina Faso. Host preference assays using odour-baited traps revealed no effect infection long-range anthropophily. However, identification blood meal origin mosquitoes showed females carrying sporozoites, mature...
In a context of increasing resistance both vectors toward main classes insecticides used in public health and parasites anti-malarial drugs, development new complementary molecules or control approaches is fundamental to achieve the objective controlling even eliminating malaria. Concerning vector control, sterile insect technique other genetic are among promising tools an integrated management strategy for malaria control. These rely not only on good understanding biology (especially during...
Abstract Whether the malaria parasite Plasmodium falciparum can manipulate mosquito host choice in ways that enhance transmission toward humans is unknown. We assessed influence of P. on blood-feeding behaviour three its major vectors ( Anopheles coluzzii, An. gambiae and arabiensis ) Burkina Faso. Host preference assays using odour-baited traps revealed no effect infection long-range anthropophily. However, identification blood meal origin mosquitoes showed females carrying sporozoites,...
The sterile insect technique (SIT) is a vector control strategy relying on the mass release of males into wild populations. Current sex separation techniques are not fully efficient and could lead to small proportion females. It therefore important evaluate effect irradiation ability released females transmit pathogens. This study aimed assess survival competence Anopheles arabiensis for Plasmodium falciparum in laboratory conditions. Pupae were irradiated at 95 Gy gamma-rays, emerging...