A5104094818- Bone health and osteoporosis research
- Bone and Joint Diseases
- Hip and Femur Fractures
- Bone Metabolism and Diseases
- Glaucoma and retinal disorders
- Vitamin D Research Studies
- Muscle metabolism and nutrition
- Nitric Oxide and Endothelin Effects
- Medical Imaging and Analysis
- Neonatal Respiratory Health Research
- Nutrition and Health in Aging
- Cardiac Imaging and Diagnostics
- Medical Imaging Techniques and Applications
- Hormonal and reproductive studies
- Diabetes and associated disorders
- Reproductive biology and impacts on aquatic species
- Body Composition Measurement Techniques
- Neurological Disorders and Treatments
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Immune Response and Inflammation
- Hypothalamic control of reproductive hormones
Stomatology Hospital
2024
Peking University
2018-2024
Beijing Chao-Yang Hospital
2022
Capital Medical University
2022
Beijing Jishuitan Hospital
2018-2022
Xuzhou Medical College
2020
Second People’s Hospital of Huai’an
2020
Sun Yat-sen University
2017
Army Medical University
2017
Daping Hospital
2017
It is generally believed that kisspeptin and gonadotropin-releasing hormone (GnRH) are required for reproduction in vertebrates. In this study, we generated gnrh3-null zebrafish found gnrh3 mutation did not impair gonad development reproductive capacity. Moreover, triple knockout mutant lacking the 2 kiss1s genes undergo normal puberty maturation. The expression of follicle-stimulating beta (fshβ) luteinizing (lhβ) was significantly altered whereas neuropeptide Y (npy), tachykinin 3 (tac3),...
Bidirectional positive relationship between periodontitis and type 2 diabetes mellitus (T2DM) has been recognized, interleukin 17 (IL-17) developmental endothelial locus-1 (Del-1) are proposed to play roles in T2DM. This study aims investigate the association of IL-17 Del-1 patients with without T2DM by measuring their salivary levels.
The effect of calcium on prevention osteoporosis and related fracture which are aging issues is unclear.The aim this study to explore the association intake with vertebral fracture.This enrolled 3,457 participants from China Action Spine Hip Status (CASH) 2013 2017.Dietary was collected using validated food frequency questionnaires (FFQ).Vertebral CT images defined as primary outcome.The mean men women were 522.75mg/day 507.21mg/day, respectively.6% reduction in odds risk observed per 100...
The etiology of age-related bone loss is less clear in men. This study aimed to observe the variations endogenous sex hormone concentrations with increasing age men, and investigate their relations mass, marrow adiposity, muscle adiposity. A total 199 community-dwelling Chinese men (aged 41 82 years) were included measured serum estradiol, testosterone, follicle-stimulating (FSH) by enzyme-linked immunosorbent assay (ELISA). Vertebral trabecular volumetric mineral density (vBMD) was...
Purpose This study evaluated the prevalence of vertebral fractures (VF) in middle-aged and elderly Chinese men women explored differences lumbar spine volumetric bone mineral density (vBMD) derived from quantitative CT (QCT) between those with a grade 1 fracture non-fractured individuals. Materials methods 3,457 participants were enrolled China Action on Spine Hip Status (CASH) had upper abdominal examinations. Vertebral identified by Genant’s semi-quantitative method lateral scout views or...
This study is a case–control to explore risk and protective factors, including clinical data bone mineral density (BMD), affecting vertebral body fragility fracture in elderly men postmenopausal women. In addition, we investigate the effectiveness of lumbar spine BMD by quantitative computed tomography (QCT) discriminating fracture. this study, 52 males 198 females with were compared sex- age-matched healthy controls analyse factors that may affect The L1–L3 BMDs measured QCT. difference...
To explore how the stiffness index of calcaneus is related to lifestyle factors, we examined associations age, and years since menopause, with among 573 community-dwelling Japanese women aged 40-89 years. Stiffness was obtained from quantitative ultrasound measurement. Body height weight were measured, which body mass (BMI) calculated. Physical activity calculated using a validated questionnaire. Dietary calcium intake amount ingested alcohol estimated by semiquantitative food frequency...
Background Calcium is widely recognized as an effective intervention for the prevention of osteoporosis. However, some recent studies and meta-analyses indicate that calcium supplements may be ineffective to prevent fracture. The association dietary intake with vertebral fracture spinal volumetric bone mineral density (vBMD) in low population unknown.
Abstract Background Osteoporotic peripheral and spinal fracture, characterized by high morbidity mortality, has become a health burden for the aging population. The inactivation of Wnt signaling been proved to promote osteoporotic fractures. Our study is identify key genes, miRNAs, pathways that possibly lead osteoporosis fracture after aberrant activation or mutation pathway. Methods Impute R package was used screen out differently expressed genes (DEGs) miRNAs in GEO datasets. STRING...