A5074855200- Radiation Dose and Imaging
- Mechanical Circulatory Support Devices
- Heart Failure Treatment and Management
- Radiology practices and education
- Appendicitis Diagnosis and Management
- Acute Kidney Injury Research
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Traumatic Brain Injury and Neurovascular Disturbances
- Ultrasound in Clinical Applications
- Cardiac pacing and defibrillation studies
- Advanced X-ray and CT Imaging
- Cardiovascular Function and Risk Factors
- Health and Medical Research Impacts
- Lanthanide and Transition Metal Complexes
- Cardiac, Anesthesia and Surgical Outcomes
- Frailty in Older Adults
- MRI in cancer diagnosis
- Ethics in Clinical Research
- Gastrointestinal disorders and treatments
- Renal and Vascular Pathologies
- Prostate Cancer Diagnosis and Treatment
- Inflammatory Bowel Disease
- Esophageal and GI Pathology
- Health Systems, Economic Evaluations, Quality of Life
University of Michigan
2016-2025
Michigan Medicine
2011-2024
National Center for Advancing Translational Sciences
2023
Michigan Center for Translational Pathology
2023
Leiden University Medical Center
2023
Medizinische Hochschule Hannover
2023
University Hospital of Wales
2023
Mallinckrodt (United States)
2023
Deaconess Hospital
2023
Beth Israel Deaconess Medical Center
2023
Purpose To determine the effect of intravenous (IV) low-osmolality iodinated contrast material (LOCM) on development post–computed tomography (CT) acute kidney injury (AKI), stratified by pre-CT estimated glomerular filtration rate (eGFR), in patients with stable renal function. Materials and Methods Institutional review board approval was obtained patient consent waived for this HIPAA-compliant, retrospective study. CT examinations performed over a 10-year period unique adult inpatients...
Purpose To determine whether intravenous low-osmolality iodinated contrast material is associated with post–computed tomography (CT) acute kidney injury (AKI). Materials and Methods Institutional review board approval was obtained patient consent waived for this HIPAA-compliant retrospective study. CT examinations performed over a 10-year period in adult inpatients sufficient serum creatinine (SCr) data were identified. A one-to-one propensity-matched matched cohort analysis multivariate of...
To determine for expert and novice radiologists repeatability of major diagnostic features scoring systems (ie, Liver Imaging Reporting Data System [LI-RADS], Organ Procurement Transplantation Network [OPTN], American Association the Study Diseases [AASLD]) hepatocellular carcinoma (HCC) by using magnetic resonance (MR) imaging.Institutional review board approval was obtained patient consent waived this HIPAA-compliant, retrospective study. The LI-RADS discussed in article refers to version...
Background: Racial disparities in access to advanced therapies for heart failure (HF) patients are well documented, although the reasons remain uncertain. We sought determine association of race on utilization ventricular assist device (VAD) and transplant among with care at VAD centers if patient preferences impact effect. Methods: performed an observational cohort study ambulatory chronic systolic HF high-risk features no contraindication enrolled 21 followed 2 years REVIVAL (Registry...
The purpose of this article is to determine whether there a dose-toxicity relationship between gadoxetate disodium and transient severe respiratory motion artifact.Gadoxetate disodium-enhanced MRI studies (559 559 patients) using fixed 20-mL (2 mL/s; n = 112) or 10-mL (1-2 447) volume at two health systems were included (dose range, 0.05-0.42 mL/kg; mean, 0.15 above-label dosing, 479 [86%]). Each dynamic phase was assigned score from 1 (none) 5 (nondiagnostic). Examinations with an...
There has been increasing legislative interest in regulating gender-affirming surgery, part due to the concern about decisional regret. The regret rate following surgery is thought be approximately 1%; however, previous studies relied heavily on ad hoc instruments.
<h3>Background</h3> Rheumatoid arthritis (RA) is associated with enhanced cardiovascular (CV) risk and subclinical vascular disease. The proinflammatory milieu has been linked to premature atherosclerosis endothelial dysfunction in RA. While interleukin 17 (IL-17) considered pathogenic RA, its role determining this disease not systematically assessed. <h3>Objectives</h3> To analyse candidate variables that might determine function various territories a cohort of patients RA receiving...
Rheumatoid arthritis (RA) is associated with heightened mortality due to atherosclerotic cardiovascular disease (CVD). Inflammatory pathways in RA negatively affect vascular physiology and promote metabolic disturbances that contribute CVD. We hypothesized the peroxisome proliferator activated receptor-γ (PPAR-γ) pioglitazone could potent vasculoprotective anti-inflammatory effects RA.One hundred forty-three non-diabetic adult patients (76.2% female, age 55.2 ± 12.1 [mean SD]) on stable...
Objective To assess endoleak detection and conspicuity using low–kiloelectron volt (keV) monochromatic reconstructions of single-source (fast-switch kilovolt [peak]) dual-energy data sets. Methods With approval the institutional review board, multiphasic computed tomographic (CT) scans for aortic endograft surveillance were retrospectively reviewed 39 patients. Two abdominal radiologists each performed 2 separate reading sessions, at 55-keV standard 75-keV reconstruction, respectively. The...
This prospective observational cohort study of high-school football athletes was performed to determine if high-acceleration head impacts (HHIs) that do not result in clinically diagnosed concussion still lead increases serum levels biomarkers indicating traumatic brain injury (TBI) asymptomatic and the longitudinal profile these over course season.
Intravenous (IV) contrast medium is sometimes withheld due to risk of complication or lack availability in patients undergoing computed tomography (CT) for abdominal pain. The from withholding understudied.
Prostate-specific antigen density and patient age were independent predictors of false-positive false-negative results for detection prostate cancer at multiparametric MRI, using the Prostate Imaging Reporting Data System version 2.
Abstract Context Lipodystrophy syndromes are rare disorders characterized by deficient adipose tissue, leading to insulin resistance, dyslipidemia, and organ system abnormalities. Objective Our goal was develop a lipodystrophy severity score (LDS) holistically capture the diverse manifestations of into numerical aid in prediction clinical outcomes and/or treatment impact. Design An 8-domain LDS developed eight disease experts consultation with patient organizations. The rated for feasibility...
Objectives/Goals: This continuous quality improvement project focuses on the efficiency and effectiveness of social media campaigns for clinical trials other health research. We analyzed data from 160 studies that recruited via Meta used results to make improvements MICHR’s Participant Recruitment campaigns. Methods/Study Population: Data 440 ad buys purchased advertising designed were collected U-M’s Research Warehouse, Meta, administrative sources. participant recruitment team...
Objectives/Goals: Using secure systems for sharing documents with external collaborators is essential all researchers. These may include protected health information (PHI) or sensitive materials like protocols, study reports, DSMB publications, presentations, abstracts, and statistical analysis plans (SAPs). Methods/Study Population: We surveyed the ACTS Biostatistics, Epidemiology, Research Design Special Interest Group (BERD-SIG) to gather about they are currently using have used in past...
Purpose To evaluate the effect of abruptly substituting gadobenate dimeglumine for gadopentetate on allergic-like reactions. Materials and Methods The institutional review board approved waived patient consent this HIPAA-compliant retrospective study. Allergic-like reactions related to gadolinium-based contrast media were assessed 2 years before 3.5 after was substituted dimeglumine. Reaction rates severity compared by using χ2 tests, Fisher exact odds ratios (ORs), confidence intervals...
Neoadjuvant therapy is increasingly utilized for pancreatic cancer patients to decrease tumor burden in anticipation of later surgical resection. However, infectious complications such as life threatening cholangitis may occur those with biliary obstruction. We hypothesized that placement metal rather than plastic stents results lower rates stent-related complications, leading improved clinical outcomes.Retrospective cohort treated by the University Michigan Multidisciplinary Pancreatic...
Purpose To compare serum creatinine (SCr) level– and estimated glomerular filtration rate (eGFR)-based screening methods for identifying adult inpatients at risk contrast medium–induced nephrotoxicity (CIN). Materials Methods Institutional review board approval was obtained; informed consent waived this HIPAA-compliant retrospective study. Computed tomographic examinations performed during 10 years in with stable renal function were identified (n = 28 390). The proportion of meeting various...