Zhenzhen Liu

ORCID: 0000-0001-6674-5396
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About
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Research Areas
  • Gastrointestinal Tumor Research and Treatment
  • Hematopoietic Stem Cell Transplantation
  • Gallbladder and Bile Duct Disorders
  • Minimally Invasive Surgical Techniques
  • Hematological disorders and diagnostics
  • Gastric Cancer Management and Outcomes
  • Leprosy Research and Treatment
  • Streptococcal Infections and Treatments
  • Colorectal Cancer Screening and Detection
  • Mycobacterium research and diagnosis
  • Eicosanoids and Hypertension Pharmacology
  • interferon and immune responses
  • Liver Disease Diagnosis and Treatment
  • Appendicitis Diagnosis and Management
  • Erythrocyte Function and Pathophysiology
  • Iron Metabolism and Disorders
  • Influenza Virus Research Studies
  • Chronic Myeloid Leukemia Treatments
  • Acute Myeloid Leukemia Research
  • Multiple Myeloma Research and Treatments
  • Intraperitoneal and Appendiceal Malignancies
  • Diverticular Disease and Complications
  • Esophageal and GI Pathology
  • Acute Lymphoblastic Leukemia research
  • Inflammasome and immune disorders

Sichuan University
2020-2024

West China Hospital of Sichuan University
2020-2024

First Affiliated Hospital of Zhengzhou University
2011-2023

Nanjing Medical University
2016

Jiangsu Province Hospital
2016

Abstract Myeloid sarcoma is a rare manifestation of acute myeloid leukemia (AML) and associated with poor overall survival (OS). The optimal treatment remains unclear. study retrospectively evaluated 118 patients who were treated at the First Affiliated Hospital Zhengzhou University from January 2010 to July 2021. All cases diagnosed by tissue biopsy. 41 underwent genetic mutation analysis. most frequent mutations KIT (16.6%), followed TET2 (14.6%), NRAS (14.6%). median time was 4 months...

10.1038/s41598-022-10831-7 article EN cc-by Scientific Reports 2022-04-26

Fever of unknown origin (FUO) is commonly defined as fever higher than 38.3 °C on several occasions during at least 3 weeks with uncertain diagnosis after a number obligatory investigations. It special type and common disease in internal medicine. However, due to its complex etiology, lack characteristic clinical manifestations, insufficient laboratory examination indicators, it often baffles clinicians diagnosis. We herein present study the etiological factors features classic provide help...

10.21037/atm-20-3875 article EN Annals of Translational Medicine 2020-06-01

Post-transplant relapse remains a principal leading cause of failure after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in patients with adult acute lymphoblastic leukemia (ALL). The aim this study was to investigate the efficacy and safety low-dose decitabine on prevention ALL allo-HSCT.In prospective study, we enrolled 34 who underwent allo-HSCT from August 2016 April 2020 received maintenance treatment transplantation. primary objectives were cumulative incidence rate...

10.3389/fonc.2021.710545 article EN cc-by Frontiers in Oncology 2021-08-16

Background Non-alcoholic fatty liver disease (NAFLD) is a complex disorder and has been closely linked to obesity. The fat mass obesity-associated (FTO) gene newly discovered related obesity, which enhances oxidative stress lipogenesis in NAFLD. forkhead transcription factor O1 (FoxO1) another important involved NAFLD, causes lipid disorders when insulin resistance appears the liver. However, interactions between FTO FoxO1 during pathogenesis of NAFLD have not fully elucidated. This study...

10.3760/cma.j.issn.0366-6999.20141017 article EN cc-by-nc-nd Chinese Medical Journal 2014-11-05

Cholecystectomy is the preferred treatment option for symptomatic gallstones. However, another gallbladder-preserving cholecystolithotomy which preserves normal physiological functions of gallbladder in patients desiring to avoid surgical resection.

10.4240/wjgs.v14.i5.470 article EN World Journal of Gastrointestinal Surgery 2022-05-25

Successful closure of postoperative defects is essential for endoscopic resection early neoplasms. The purse-string suture (EPSS) using a double-channel colonoscope has been shown to be safe and effective. This method involves the interaction endoloop metal clips through two separate endoscope channels [1]. However, single-channel colonoscopes are more popular in clinical practice because their longer length, flexible operation, cheaper price, especially when used right colon. We report on...

10.1055/s-0042-104192 article EN Endoscopy 2016-04-14

To evaluate the role of endoscopic retrograde appendicography for diagnosis acute appendicitis.We retrospectively analyzed 33 patients (20 men and 13 women, average age 44±18 years) with suspected appendicitis between December 2016 November 2018. Endoscopic direct-vision imaging or fluoroscopic was performed to separate from actual appendicitis. The success rate, complications, recurrence rate were recorded.Acute ruled out by normal in 8 (24%) confirmed 23 (70%). In 2 (6%), appendiceal...

10.2147/ijgm.s336040 article EN cc-by-nc International Journal of General Medicine 2021-10-01
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