Chao Han

ORCID: 0000-0003-3923-8537
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About
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Research Areas
  • Visual perception and processing mechanisms
  • Spectroscopy and Chemometric Analyses
  • Glaucoma and retinal disorders
  • Neural dynamics and brain function
  • Ophthalmology and Visual Impairment Studies
  • Metal and Thin Film Mechanics
  • Cardiovascular Disease and Adiposity
  • Remote Sensing in Agriculture
  • Advanced Measurement and Detection Methods
  • High-Temperature Coating Behaviors
  • Remote Sensing and Land Use
  • Neurobiology and Insect Physiology Research
  • Energetic Materials and Combustion
  • Adipokines, Inflammation, and Metabolic Diseases
  • Data Visualization and Analytics
  • Advanced materials and composites
  • Thermal and Kinetic Analysis
  • Retinoids in leukemia and cellular processes
  • Advanced Optical Imaging Technologies
  • High Entropy Alloys Studies
  • Optical Systems and Laser Technology
  • Metallic Glasses and Amorphous Alloys
  • Infrared Target Detection Methodologies
  • Image Retrieval and Classification Techniques
  • Water Quality Monitoring and Analysis

Nanjing Medical University
2025

Army Medical University
2024

Peking University
2011-2024

Peking University Cancer Hospital
2023-2024

Jiangsu Institute of Metrology
2023-2024

The Ohio State University
2016-2023

SUNY College of Optometry
2016-2023

Chinese Institute for Brain Research
2016-2023

Beijing Normal University
2016-2023

Qingdao University
2009-2023

In visual analytics, sensemaking is facilitated through interactive exploration of data. Throughout this dynamic process, users combine their domain knowledge with the dataset to create insight. Therefore, analytic tools exist that aid by providing various interaction techniques focus on allowing change representation adjusting parameters underlying statistical model. However, we postulate process not focused a series parameter adjustments, but instead, perceived connections and patterns...

10.1109/vast.2011.6102449 article EN 2011-10-01

Lycium barbarum polysaccharide (LBP) has traditionally been used in Chinese medicine as a chief ingredient of (wolf berry/goji berry) for the treatment various diseases with symptoms frequent drinking and urination. This study was conducted randomized, controlled clinical trial. A total 67 patients type 2 diabetes (30 control group 37 LBP group) were enrolled this prospective, double-blind (administration at 300mg/day body weight). In order to observe hypoglycemic lipid-lowering activity...

10.2174/1573406410666141110153858 article EN Medicinal Chemistry 2015-04-29

Thymus is the main immune organ which responsible for production of self-tolerant and functional T cells, but it shrinks rapidly with age after birth. Although studies have researched thymus development involution in mouse, critical regulators that arise human remain unclear. We collected public single-cell transcriptomic sequencing (scRNA-seq) datasets containing 350,678 cells from 36 samples, integrated them as a cell atlas thymus. Clinical samples were experiments performed validation....

10.3389/fimmu.2024.1322214 article EN cc-by Frontiers in Immunology 2024-01-22

Ocular complications associated with diabetes mellitus are progressive and becoming one of the most important causes morbidity worldwide. The purpose study is to evaluate protective effect Polygonatum sibiricum polysaccharide, an component sibiricum, on ocular in streptozotocin-induced rats. Sprague Dawley rats were made diabetic streptozotocin(60 mg/kg, i.v.) then treated polysaccharide 200, 400 800 mg/kg.d by gavage for 12 weeks. Biochemical analysis indicated that lowered levels fasting...

10.1177/1535370216663866 article EN Experimental Biology and Medicine 2016-08-11

Summary This study was designed to radiographically evaluate the effect of surface macro‐and microstructures within coronal portion external hex implant at marginal bone change after loading. The fifty‐four patients included in were randomly assigned treatment groups with rough‐surface implants (TiUnite, n = 45), a hybrid smooth and rough (Restore, 45) or microthreads (Hexplant, 45). Clinical radiographic examinations conducted time loading (baseline) 1‐year post‐loading. A three‐level...

10.1111/j.1365-2842.2009.01988.x article EN Journal of Oral Rehabilitation 2009-08-21

The metabolic syndrome (MetS) is a constellation of clinical features that include central obesity, hypertension, atherogenic dyslipidemia, and insulin resistance. However, the concept remains controversial; it has been debated whether MetS represents nothing more than simultaneous co-occurrence individual risk factors or there are common shared pathophysiological mechanisms link components.

10.1161/circulationaha.110.990333 article EN Circulation 2011-06-21

Summary The aim of this study was to evaluate the change marginal bone level radiographically around three different implant systems after 3 years in function. Fifty-four patients were included and randomly assigned treatment groups rough-surface implants (TiUnite, n = 37), hybrid smooth (Restore, 38) rough surface with microthread (Hexplant, 45). Clinical radiographic examinations conducted at time loading (baseline), 1 loading. A three-level mixed-effect analysis covariance (ancova) used...

10.1111/j.1365-2842.2010.02083.x article EN Journal of Oral Rehabilitation 2010-02-22

Two incongruent images viewed by the two eyes cause binocular rivalry, during which observers perceive continuous alternations between these visual images. Previous studies in both humans and monkeys have shown that primary cortex (V1) plays a critical role rivalry perception. However, it is unclear whether activity observed V1 relies on conscious influences. Here, we examine responses of under general anesthesia. With intrinsic signal optical imaging single-trial analysis, alternating...

10.1523/jneurosci.3660-15.2016 article EN cc-by-nc-sa Journal of Neuroscience 2016-03-16

Abstract Leman et al. and Endert develop an interactive data visualization framework called visual to parametric interaction (V2PI). With V2PI, experts may explore visually (assess multiple visualizations) based on their judgments underlying analytic method. Specifically, V2PI offers a deterministic procedure quantify expert update analytical parameters create new visualizations. In this article, we explain from probabilistic perspective Bayesian analytics (BaVA). We model probabilistically,...

10.1002/sam.11253 article EN Statistical Analysis and Data Mining The ASA Data Science Journal 2015-01-07

Purpose: To evaluate the characteristics, anatomical success rate, and factors that may affect of rhegmatogenous retinal detachment in patients their 20s.Methods: We retrospectively analyzed medical records aged 20-29 years who underwent surgery for from January 2018 to December 2022. examined such as sex, age, duration illness, preoperative best corrected visual acuity, presence underlying diseases, proliferative vitreoretinopathy, lattice degeneration, macular involvement, extent at...

10.3341/jkos.2025.66.3.158 article EN Journal of the Korean Ophthalmological Society 2025-03-15

summary The purpose of this study was to evaluate the geometry and surface characteristics osseointegration after functional loading by radiographic, periodontal histomorphometric analyses. We analysed three groups implants with different using experimental dogs. control group received Brånemark (group 1). Group 2 3 each had a 0·5‐mm pitch height but differed in characteristics. were machine surfaced thermally oxidized at 800 °C for h pure oxygen atmosphere. For these experiments, which used...

10.1111/j.1365-2842.2006.01653.x article EN Journal of Oral Rehabilitation 2006-07-20

Background: Lymphocyte-to-monocyte ratio (LMR) is involved in all stages of coronary atherosclerosis and related to artery disease (CAD). However, the correlation between LMR plaque burden CAD not clearly elucidated. Therefore, this study aimed investigate their patients with CAD. Methods: A total 1953 consecutive eligible inpatients suspected were retrospectively included study. They assigned into (n = 564) non-CAD groups 1389). All underwent computed tomographic angiography evaluate...

10.1097/mca.0000000000000857 article EN cc-by-nc-nd Coronary Artery Disease 2020-02-22

Non-alcoholic fatty liver disease (NAFLD) is a common associated with metabolic syndrome and can lead to life-threatening complications like hepatic carcinoma cirrhosis. Exenatide, glucagon-like peptide-1 (GLP-1) receptor agonist antidiabetic drug, has the capacity overcome insulin resistance attenuate steatosis but specific underlying mechanism unclear. This study was designed investigate molecular mechanisms of exenatide therapy on NAFLD. We used in vivo vitro techniques protective effects...

10.1590/1414-431x20187299 article EN cc-by Brazilian Journal of Medical and Biological Research 2018-01-01

This study aimed to investigate the correlation between triglyceride glucose (TyG) index and coronary artery disease (CAD) with type 2 diabetes mellitus (T2DM) identify risk associated TyG in different subgroups.A total of 1665 eligible inpatients (CAD T2DM group [n = 680], non-coronary without 985]) were consecutively enrolled this study. They assigned into 4 subgroups: middle-aged, elderly, male, female subgroups. Receiver operating characteristic curve diagnostic test a logistic...

10.1097/md.0000000000025025 article EN cc-by-nc Medicine 2021-03-03

Our objective in this study was to develop spectral absorption indices for prediction of leaf chlorophyll concentration based on blue/yellow/red/ edge absorption spectrum. Two field experiments were conducted the response index on spectra rice. The ultimate, penultimate and third expanded leaves sampled measurements main stem three rice varieties at different growth stages select wavelength position near zero better algorithms estimating concentration. Some indices called blue/yellow/red/...

10.5897/jpbcs.9000004 article EN Journal of Plant Breeding and Crop Science 2009-07-31

The ability to extract the shape of moving objects is fundamental visual perception. However, where such computations are processed in system unknown. To address this question, we used intrinsic signal optical imaging awake monkeys examine cortical response perceptual contours defined by motion contrast (motion boundaries, MBs). We found that MB stimuli elicit a robust orientation area V2. Orientation maps derived from subtraction orthogonal aligned well with obtained luminance gratings...

10.1093/cercor/bhu235 article EN Cerebral Cortex 2014-09-26

Two core processes underlie 3-D binocular vision. The first, a combination/summation process, integrates similar feature signals from the two eye channels to form representation. second, inhibitory suppresses interocular conflicting or falsely matched representations establish single Having an intrinsic imbalance within one both can cause sensory dominance (SED), related imbalances of combination (SEDcombo) and/or inhibition (SEDinhibition). While much has recently been revealed about...

10.1167/iovs.18-24342 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2018-10-24

C-11 acetate PET imaging allows quantification of myocardial oxidative metabolism. We sought to assess the reproducibility such analysis with Carimas software. The oxygen consumption rate was assessed via a kmono index—the clearance constant mono-exponential function fitted curve. Two observers different experience levels—a novice and an expert—analysed 53 studies—each study twice. These results were compared using Bland–Altman (BA) plots global kmono-s obtained earlier validated reference...

10.1093/ehjci/jeu289 article EN European Heart Journal - Cardiovascular Imaging 2014-12-22
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