A5101724519- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Marine and coastal ecosystems
- Magnesium Alloys: Properties and Applications
- Ocean Acidification Effects and Responses
- Advanced biosensing and bioanalysis techniques
- Aluminum Alloys Composites Properties
- Methane Hydrates and Related Phenomena
- Luminescence and Fluorescent Materials
- Marine Biology and Ecology Research
- RNA Interference and Gene Delivery
- Corrosion Behavior and Inhibition
- Atmospheric and Environmental Gas Dynamics
- Biosensors and Analytical Detection
- Orthopaedic implants and arthroplasty
- Supramolecular Self-Assembly in Materials
- Molecular Sensors and Ion Detection
- Polydiacetylene-based materials and applications
- Infrared Thermography in Medicine
- RNA modifications and cancer
- Marine and coastal plant biology
- DNA and Nucleic Acid Chemistry
- Air Quality and Health Impacts
- Coral and Marine Ecosystems Studies
- Atmospheric chemistry and aerosols
Renji Hospital
2025
Shanghai Jiao Tong University
2024-2025
National Marine Environmental Monitoring Center
2015-2024
China National Environmental Monitoring Center
2015-2024
Guangxi Medical University
2024
CiS Research Institute for Micro Sensors and Photovoltaics
2024
Shanghai Children's Medical Center
2024
Wuhan Institute of Technology
2024
Nanfang Hospital
2023
Southern Medical University
2022-2023
As a biomarker for early cancer diagnosis, telomerase are one of the promising targets therapeutics. Inspired by fluorescent emission principle aggregation-induced fluorogens, we creatively designed an AIE-based turn-on method to detect activity from cell extracts. A positively charged fluorogen (TPE-Z) is not when freely diffused in solution. The fluorescence TPE-Z enhanced with elongation DNA strand which could light up telomere process. By exploitation it, can different lines (E-J, HeLa,...
Abstract Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3), an RNA-binding protein, is associated with tumorigenesis and progression. However, the exact molecular mechanisms of IGF2BP3 in colorectal cancer (CRC) oncogenesis, progression, drug resistance remain unclear. This study found that was upregulated CRC tissues. Clinically, elevated level predictive a poor prognosis. Functionally, enhances progression both vitro vivo. Mechanistically, promotes epidermal receptor (EGFR)...
Purpose To evaluate the MMP-inhibitory effect of chlorhexidine when incorporated in primer a two-step selfetching adhesive (Clearfil SE Bond). Materials and methods Powdered dentin made from human teeth was treated with Clearfil Bond primers containing different concentrations for 20 s or 2 min. The collagenolytic activity powder assayed using fluorescein-labelled collagen. Results Untreated contains low but measurable level intrinsic activity, which significantly inhibited by 0.05%...
Abstract The clustered regularly interspaced short palindromic repeat (CRISPR)‐associated system has displayed promise in visualizing the dynamics of target loci living cells, which is important for studying genome regulation. However, developing a cell‐friendly and rapid transfection method achieving dynamic long‐term genomic imaging cells with high specificity accuracy still challenging. Herein, robust versatile presented that employs barrel‐shaped DNA nanostructure (TUBE) modified...
We describe the stepwise synthesis of precise polymeric objects programmed by a 3D DNA tube transformed from common 2D tile as biotemplate for atom transfer radical polymerization.
<bold>(S)/(R)1</bold> enantioselectively self-assemble to form a gel or solution with one enantiomer of <bold>(S)/(R)BINAM</bold> specific selectivity.
Abstract For high corrosion resistance and extensively modified biodegradable Mg-based alloys composites for bone implants, a new matrix model prepared by powder metallurgy is discussed developed. In this research, Mg-5 wt.%Zn were selected as case. And they impacted hot extrusion aging treatments to construct microstructure with different characteristics. Their self-forming product layer in Ringer's solution, behavior mechanism minutely investigated vitro degradation, electrochemical...
Chiral Pt(<sc>ii</sc>) complexes bearing bridging Salen ligands exhibit strong AIP through well-tuned intramolecular Pt–Pt interactions and multiple intermolecular interactions.
Abstract Osteosarcoma is a malignant primary bone tumor, which often associates with pulmonary metastasis. The radical surgery of osteosarcoma requires internal orthopedic implants. Therefore, implants antitumor properties should be developed. Magnesium (Mg) and its alloys possess great potential as materials, given their biodegradable properties, superior osteogenesis performance, features. However, problems arise uncontrolled degradation rates unknown mechanisms. In our study, when...
It is essential to estimate the indoor pesticides/insecticides exposure risk since reports show that 80% of human pesticides occurs indoors. As one three major contamination sources, surface collected contributed significantly this risk. Here, a highly sensitive liquid freestanding membrane (FSM) SERS method based on iodide modified silver nanoparticles (Ag NPs) was developed for quantitative detection insecticide deltamethrin (DM) residues in solution phase samples and surfaces with good...
In order to design a potential biodegradable implant, which combines with fine mechanical and antimicrobial properties, Mg-4Y-1Ag (mass fraction, %) alloys were produced by permanent mold casting then hot extrusion. The microstructure, behavior, anti-corrosion properties of the experimental comprehensively investigated. results showed that α-Mg, Mg24Y5 (ε), AgMg4 phases existed in Mg-4Y-1Ag. grain size was greatly refined through hot-extrusion. as-extruded alloy exhibit an ultimate tensile...
Fluorescent organic materials are commonly π-conjugated planar molecules. In the present work, however, we report a novel class of nonconjugated fluorescent molecular cages trinuclear fluoroborate complexes (nine samples) with salicylaldehyde-based Schiff base ligands. Owing to stress from lone pair electrons N atom in triethylamine bridge, these B(III) exhibit unusual enantiomers tripodlike side-single-opening structure. They emit blue, green, and red emission large Stokes shifts (up 159...
A series of Mg–Zn alloys, including Mg–1%Zn, Mg–2.5%Zn, Mg–25%Zn, Mg–50%Zn, Mg–75%Zn and Mg–99%Zn alloys (at%), were designed produced by powder metallurgy for bone tissue engineering. The effects intermetallic phases on microstructures, mechanical properties corrosion resistance Mg matrix Zn studied compared to select the suitable candidates biodegradable metallic implants. results showed that Mg–2.5%Zn alloy could be treated as good candidate engineering due its properties, relatively low...
Cytotoxicity of CuO nanoparticles (NPs) are an impediment in utilizing them as effective nanocarriers chemotherapeutic drugs for targeted drug delivery nasopharyngeal cancer. In our current study, we have designed a two-step synthesis and coating NPs with different concentrations PLGA (polylactide-co-glycolide) to reduce the cytotoxicity. This was further conjugated folic acid enhance targeting specific tissue. The multiple loaded were two potent anticancer doxorubicin docetaxel. A complete...