Tim Forgan
A5023484069- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Abdominal Trauma and Injuries
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Abdominal Surgery and Complications
- Global Health and Surgery
- Anorectal Disease Treatments and Outcomes
- Trauma Management and Diagnosis
- Immune Response and Inflammation
- Immune cells in cancer
- Surgical Simulation and Training
- Diverticular Disease and Complications
- Mycobacterium research and diagnosis
- Ureteral procedures and complications
Stellenbosch University
2020-2024
Tygerberg Hospital
2020-2024
St. Vincent's University Hospital
2021-2022
Abstract Gut dysbiosis contributes to the development of a dysfunctional gut barrier, facilitating translocation bacteria and inflammagens, is implicated in colorectal cancer (CRC) pathogenesis. Such ‘leaky gut’ conditions result systemic inflammation, which hallmark increased hypercoagulability. Fluorescence antibody confocal microscopy was used determine circulating levels lipopolysaccharide (LPS) control CRC populations. Here we showed that LPS are significantly elevated population. We...
The molecular profile of early-onset colonic cancer is undefined. This study evaluated clinicopathological features and oncological outcomes young patients with according to microsatellite status.
In this study of 400 patients with early-onset rectal cancer, 12.5 per cent demonstrated microsatellite instability (MSI). MSI was associated a reduced likelihood nodal positivity, an increased rate pathological complete response, and improved disease-specific survival.
ABSTRACT Background: The surgical management of penetrating abdominal trauma can be challenging, and despite improvements in diagnostics treatment, mortality morbidity rates remain high. Intraoperative fluorescence angiography with indocyanine green (ICG-FA) is currently implemented many elective settings. However, there are few data regarding the usability ICG-FA emergency surgery, to our knowledge, has not been evaluated trauma. Hence, objective was determine feasibility Materials methods:...
The surgical management of penetrating hollow visceral injuries includes primary repair or exteriorization. Tissue perfusion at the site gastrointestinal suture may be challenging to assess and is vulnerable local energy transfer-related injury, micro- macro-circulatory insufficiency, splanchnic vasoconstriction for various reasons. Breakdown lines can lead potentially life-threatening complications. intraoperative use Indocyanine Green Fluorescence Angiography (ICG-FA) reduce risk...
Background: Extra-levator abdominoperineal resection (ELAPE) performed in the prone jack-knife position is a new technique developing world.Literature on outcomes of ELAPE country context scarce.The objective was to assess early after position, and compare patients who underwent abdominal part procedure laparoscopically with an open group, at tertiary institution Cape Town.Methods: Records for rectal adenocarcinoma from February 2011 2017 Tygerberg Hospital were retrospectively...