A5070285101- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Transplantation Techniques and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- MRI in cancer diagnosis
- Pharmacology and Obesity Treatment
- COVID-19 diagnosis using AI
- Thermal Regulation in Medicine
- Diabetes and associated disorders
- Enzyme Production and Characterization
- Pancreatitis Pathology and Treatment
- Metabolism and Genetic Disorders
- Diagnosis and treatment of tuberculosis
- Thermoregulation and physiological responses
- Inflammatory Bowel Disease
- Climate Change and Health Impacts
- Cancer-related molecular mechanisms research
- Viral gastroenteritis research and epidemiology
- Viral-associated cancers and disorders
- Metabolism, Diabetes, and Cancer
- Child Nutrition and Feeding Issues
- Infant Nutrition and Health
Icahn School of Medicine at Mount Sinai
2020-2024
Hospital Universitario Virgen de la Arrixaca
2018-2024
Universidad de Murcia
2019-2022
Instituto Murciano de Investigación Biosanitaria
2019-2022
Abstract Post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are debilitating, clinically heterogeneous and unknown molecular etiology. A transcriptome-wide investigation was performed in 165 acutely infected hospitalized individuals who were followed into the post-acute period. Distinct gene expression signatures already present whole blood during infection, with innate adaptive immune cells implicated different symptoms. Two clusters exhibited...
Background There is a need for noninvasive methods the diagnosis and monitoring of portal hypertension (PH). Purpose To 1) assess correlation liver spleen T 1 1ρ measurements with pressures in patients chronic disease, 2) to compare diagnostic performance relaxation parameters radiological assessment PH. Study Type Prospective. Subjects Twenty‐five (M/F 16/9, mean age 56 years, range 21–78 years) undergoing pressure (hepatic venous gradient [HVPG]) measurements. Field Strength/Sequence 1.5T...
Current consensus recommendations define small bowel strictures [SBS] in Crohn's disease [CD] on imaging as luminal narrowing with unequivocal upstream dilation. The aim of this study was to [1] evaluate the performance cross-sectional for SBS diagnosis CD using SB dilation and or without dilation, [2] compare diagnostic computed tomography [CT] magnetic resonance enterography [MRE] diagnosis. In total, 111 patients [81 pathologically confirmed SBS, 30 controls] who underwent CT and/or MRE...
To evaluate the value of pre-treatment MRI-based radiomics in patients with hepatocellular carcinoma (HCC) for prediction response to Yttrium 90 radiation segmentectomy.
Abstract Introduction Severe COVID-19 leads to important changes in circulating immune-related proteins. To date it has been difficult understand their temporal relationship and identify cytokines that are drivers of severe outcomes underlie differences between sexes. Here, we measured 147 proteins during acute investigate these questions. Methods We protein abundances using the SOMAscan nucleic acid aptamer panel two large independent hospital-based cohorts Canada United States. fit...
Objective The aim of this study was to compare in vivo vs ex liver stiffness rats with acoustic radiation force impulse (ARFI) elastography using the histological findings as gold standard. Methods Eighteen male Wistar aged 16–18 months were divided into a control group (n = 6) and obese 12). Liver measured shear wave velocity (SWV) ARFI technique both vivo. degree fibrosis, steatosis inflammation evaluated findings. Pearson's correlation coefficient applied relate SWV values parameters....
OBJECTIVE. The purposes of this study were to determine the medium-term effect ultrasound-guided infiltration platelet-rich plasma (PRP) on partial tears supraspinatus tendon (SST) and identify prognostic indicators an unfavorable outcome. SUBJECTS AND METHODS. Over a period 4 years, patients with SST tear smaller than 1.5 cm referred for PRP (1 mL) shoulder pain lasting more 3 months recruited consecutively. MRI was used analyze type acromion presence acromioclavicular (AC) arthrosis....
Despite extraordinary international efforts to dampen the spread and understand mechanisms behind SARS-CoV-2 infections, accessible predictive biomarkers directly applicable in clinic are yet be discovered. Recent studies have revealed that diverse types of assays bear limited power for COVID-19 outcomes. Here, we harness chest computed tomography (CT) combination with plasma cytokines using a machine learning k-fold cross-validation approach predicting death during hospitalization maximum...
ABSTRACT Despite extraordinary international efforts to dampen the spread and understand mechanisms behind SARS-CoV-2 infections, accessible predictive biomarkers directly applicable in clinic are yet be discovered. Recent studies have revealed that diverse types of assays bear limited power for COVID-19 outcomes. Here, we harness chest CT combination with plasma cytokines using a machine learning approach predicting death during hospitalization maximum severity degree patients. Patients...
Defining reference intervals in experimental animal models plays a crucial role pre-clinical studies. The hepatic parameters healthy animals provide useful information about type and extension of damage. However, the majority cases, to obtain them require an invasive techniques. Our study combines these determinations with dynamic functional test imaging techniques implement non-invasive protocol for liver evaluation. aim was determine function, perfusion parenchyma attenuation analytical...
Introduction The limitation of donor organs has an important influence on the number patients who can undergo a liver transplant (LT), even more due malignant causes. To avoid mortality waiting list, it is crucial to expand criteria for organ acceptance. objective this study measure Donor Age and Comorbidities overall Graft Survival between received from diseased donors less than 75 years older. Patients Methods From prospective database consecutive 100 underwent LT Hepatocellular Carcinoma...
Introduction and Objective: Orlistat is an intestinal lipase inhibitor drug, approved by the Food Drug Administration in 1998, which has been shown to be superior placebo weight loss currently recommended obese patients along with a hypocaloric diet, assuming of approximately 30%. Although most frequent secondary effect steatorrhea, Fulminant Liver Failure associated this even reaching liver transplantation 3 patients. We present case urgent due acute failure drug treatment. Clinical A 42...
Introduction and Objective The Fulminant Liver Failure secondary to a maintained hypoxia of the organ, due Heat Stroke is very rare entity with ominous prognosis. There still controversy about Transplantation in this context, being an exceptional indication. We provide our experience regarding recent case. Clinical Case A 32 years old man no comorbidities, who while he was working summer afternoon Murcia as delivery boy, suffered cognitive deterioration, coma, fever 42°C seizures. Faced...