A5067568269- Genetics and Physical Performance
- Muscle metabolism and nutrition
- Cardiovascular Effects of Exercise
- Adipose Tissue and Metabolism
- Sports Performance and Training
- Knee injuries and reconstruction techniques
- Peroxisome Proliferator-Activated Receptors
- Tendon Structure and Treatment
- Exercise and Physiological Responses
- Parasitic Infections and Diagnostics
- Obesity, Physical Activity, Diet
- Muscle Physiology and Disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Sports injuries and prevention
- Amoebic Infections and Treatments
- Lipid metabolism and biosynthesis
- Genetic Associations and Epidemiology
- Cardiomyopathy and Myosin Studies
- Eating Disorders and Behaviors
- Osteoarthritis Treatment and Mechanisms
- Legionella and Acanthamoeba research
- IL-33, ST2, and ILC Pathways
- Regulation of Appetite and Obesity
- Cardiovascular Disease and Adiposity
- Orthopedic Surgery and Rehabilitation
Gdansk University of Physical Education and Sport
2014-2024
University of Cagliari
2023
University of Szczecin
2009-2018
West Pomeranian University of Technology
2013-2015
Instytut Sportu
2015
Volga Region State Academy of Physical Culture, Sports and Tourism
2015
Abstract The COL5A1 and COL12A1 variants are independently associated with modulating the risk of anterior cruciate ligament (ACL) rupture in females. objective this study was to further investigate if COL3A1 COL6A1 independently, as well as, collagen gene–gene interactions, modulate ACL risk. Three hundred thirty‐three South African (SA, n = 242) Polish (PL, 91) participants diagnosed ruptures 378 controls (235 SA 143 PL) were recruited. Participants genotyped for rs1800255 G/A, rs12722...
Pickering, C, Suraci, B, Semenova, EA, Boulygina, Kostryukova, ES, Kulemin, NA, Borisov, OV, Khabibova, SA, Larin, AK, Pavlenko, AV, Lyubaeva, EV, Popov, DV, Lysenko, Vepkhvadze, TF, Lednev, EM, Leońska-Duniec, A, Pająk, Chycki, J, Moska, W, Lulińska-Kuklik, E, Dornowski, M, Maszczyk, Bradley, Kana-ah, Cięszczyk, P, Generozov, and Ahmetov, II. A genome-wide association study of sprint performance in elite youth football players. J Strength Cond Res 33(9): 2344-2351, 2019-Sprint speed is an...
Background: Numerous data suggest that aerobic-type exercise improves lipoprotein-lipid profiles, cardiorespiratory fitness and body composition in young women. The aim of this study was to evaluate the biological response high-low impact aerobic among
Borrelia burgdorferi sensu lato, carried by Ixodes ticks, is one of the most significant human pathogens, causing Lyme disease. As there no standardized PCR method for detection and identification spirochaete DNA, we out a comparative analysis using set complementary primers three regions in genomic DNA these bacteria (genes fla rrs non-coding rrs-rrlA region). extracted from 579 ricinus ticks was subjected to nested PCR. examined spirochaetes detected 43 (7.4 %) lysates when gene used as...
Alpha-actinins are an ancient family of actin-binding proteins that play structural and regulatory roles in cytoskeletal organization. In skeletal muscle, α-actinin-3 protein is important component the Z disc, where it anchors actin thin filaments, helping to maintain myofibrillar array. A common nonsense polymorphism codon 577 ACTN3 gene (R577X) results deficiency XX homozygotes. Based on knowledge about role R557X muscle function, we postulated genetic could also improve sprint power...
The aim of this study was to examine the association +1245G/T polymorphisms in COL1A1 gene with ACL ruptures Polish male recreational skiers a case-control study.A total 138 surgically diagnosed primary ruptures, all whom qualified for ligament reconstruction, were recruited study. control group comprised 183 apparently healthy comparable level exposure injury, none had any self-reported history or tendon injury. DNA samples extracted from oral epithelial cells genotyped using real-time PCR...
Obesity has been recognized as a worldwide growing problem, producing many pathologies including the promotion of "proinflammatory state." The etiology human obesity is still only partially understood; however, genetic background proved. Its nature complex, and currently, it appears that combined effects interactions among multiple genes should receive more attention. Due to fact promotes proinflammatory conditions, in this study, we investigated polymorphism IL-1 family healthy people with...
Thus far, genetic studies of the renin-angiotensin system (RAS) with respect to athletic performance or athlete status have mainly focused on angiotensin-converting enzyme gene and its insertion/deletion polymorphism. The aim this study was investigate functional rs699 (M235T) polymorphism in angiotensinogen (AGT), second most important RAS, for association level performance. included 123 endurance athletes 100 power-oriented athletes, who were classified as elite sub-elite according...
Abstract The purpose of this study was to examine the association BstUI RFLP C/T (rs 12722) and DpnII 13946) COL5A1 polymorphisms, individually as haplotypes, with anterior cruciate ligament ruptures in recreational skiers. Subjects were 138 male skiers surgically diagnosed primary ruptures. control group consisted 183 apparently healthy skiers, who without any self-reported history or tendon injury. DNA extracted from buccal cells donated by subjects genotyping carried out using real-time...
The first described obesity-susceptibility gene was the fat mass and obesity-associated (FTO) gene. However, knowledge about FTO's potential modifying effect on changes in body weight achieved through a training program is still limited. We decided to study association between FTO A/T polymorphism (rs9939609) obesity-related traits. Additionally, we investigated whether composition, as well metabolic variables observed physically active participants, are modulated by polymorphism.A group of...
Exercise-induced oxidative stress is a state that primarily occurs in athletes involved high-intensity sports when pro-oxidants overwhelm the antioxidant defense system to oxidize proteins, lipids, and nucleic acids. During exercise, linked muscle metabolism damage, because exercise increases free radical production. The T allele of Ala16Val (rs4880 C/T) polymorphism mitochondrial superoxide dismutase 2 (SOD2) gene has been reported reduce SOD2 efficiency against stress. In present study we...
Abstract One of the most severe injuries sustained by athletes is rupture anterior cruciate ligament (ACL). Recent investigations suggest that a predisposition for ACL may be result specific genetic sequence variants. In light this, we decided to investigate whether COL12A1 A9285G polymorphism was associated with ruptures in Polish football players. We compared genotypic and allelic frequencies two groups athletes: 91 male players (23 ± 3 years) surgically diagnosed primary who qualified...
We hypothesized that the ACE ID / ACTN3 R577X genotype combination was associated with sprint and endurance performance. Therefore, purpose of present study to determine interaction between both polymorphisms performance in swimmers. Genomic DNA extracted from oral epithelial cells using GenElute Mammalian Miniprep Kit (Sigma, Germany). All samples were genotyped a real-time poly- merase chain reaction. The I/D frequencies met Hardy-Weinberg expectations swimmers controls. When two swimmer...
The aims of this study were to determine the distribution AMPD1 genotype among groups high-level Polish power-oriented athletes, and investigate potential associations between genetic polymorphism in exon 2 gene athlete status. Altogether, 158 male athletes genotyped by PCR-RFLP. control group comprised 160 unrelated volunteers. We observed significant differences when all (89.25% CC, 10.75% CT, 0.00% TT; P = 0.0025) compared with controls (75.00% 23.75% 1.25% TT). A deficiency T allele was...
It has been suggested that DNA hypomethylation because of poorer effectiveness the 5,10-methylenetetrahydrofolate reductase (MTHFR) enzyme induces muscular growth. We hypothesised common, functional 1298A>C polymorphism in MTHFR gene is associated with athletic status. To test this hypothesis, we investigated distribution variant Polish (n = 302) and Russian 842) athletes divided into four groups: endurance, strength-endurance, sprint-strength as well 1540 control participants. found...
The aim of the study was to evaluate association between swimming performance and -9/+9 (rs5810761) polymorphism within BDKRB2 gene in successful competitive swimmers. Best individual results expressed FINA points achieved at short, middle long distance events 157 well-trained Polish swimmers were incorporated into an analysis. Athletes' genotype allele distributions analysed comparison 230 unrelated sedentary subjects who served as controls with χ(2) test. All samples genotyped for using...
Abstract Muscle stiffness, muscle elasticity and explosive strength are the main components of athletes’ performance they show a sex-based as well ethnicity variation. stiffness is thought to be one risk factors associated with sports injuries less common in females than males. These observations may explained by circulating levels sex hormones their specific receptors. It has been shown that higher estrogen lower responsible for suppression collagen synthesis. these properties, at least...
There is a wide range of individual variability in the change body weight response to exercise, and this partly depends on genetic factors. The study aimed determine DNA polymorphisms associated with fat loss efficiency untrained women normal 12-week aerobic training program using GWAS approach, followed by cross-sectional athletes. involved 126 young Polish (age 21.4 ± 1.7 years; mass index (BMI): 21.7 (2.4) kg/m2) 550 Russian athletes (229 women, age 23.0 4.1; 321 men, 23.9 4.7). We...
The aim of the presented study was to work out an effective method extraction DNA from Giardia intestinalis cysts as well a sensitive and specific for detection this protozoan using polymerase chain reaction (PCR). Twelve protocols have been compared. Purification were preceded by additional actions in order destroy cysts' wall. highest effectiveness obtained case alternating application freezing samples liquid nitrogen their incubation water bath temperature 100 ˚C, then with QIAamp Tissue...
The skeletal muscle-specific isoform of adenosine monophosphate deaminase (AMPD) is one the most important regulators muscle energy metabolism. A nonsense C to T transition in nucleotide 34 (C34T) exon 2 AMPD1 gene converts codon CAA into premature stop-codon TAA. 127 Polish male rowers including Olympic and world champions were recruited for this study. Controls samples obtained from 251 unrelated volunteers. Statistically significant differences genotype distribution observed when only a...