A5085765549- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Respiratory Support and Mechanisms
- Anesthesia and Neurotoxicity Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Trauma and Emergency Care Studies
- Nausea and vomiting management
- Cardiovascular and Diving-Related Complications
- Meta-analysis and systematic reviews
- Tracheal and airway disorders
- Cardiac Arrest and Resuscitation
- Patient Safety and Medication Errors
- Healthcare Systems and Technology
- Neonatal Respiratory Health Research
- Blood transfusion and management
- Inflammatory mediators and NSAID effects
- Pediatric Pain Management Techniques
- Abdominal Trauma and Injuries
- Health Sciences Research and Education
- Aortic Disease and Treatment Approaches
- Child Development and Digital Technology
Children's Hospital of Eastern Ontario
2014-2024
University of Ottawa
2014-2024
University of Toronto
2020
Health Sciences Centre
2019
Women's College Hospital
2019
University Health Network
2019
Agricultural Research Institute of Ontario
2008-2018
Pain and Rehabilitation Medicine
2017
Ottawa Hospital
1999-2005
Chalmers University of Technology
2005
Pediatric patients who undergo posterior spinal fusion surgery to correct scoliosis often require multiple blood transfusions. Tranexamic acid is a synthetic antifibrinolytic drug that reduces transfusion requirements in cardiac and total knee arthroplasty. We evaluated the efficacy of prophylactic tranexamic reduce perioperative prospective, double-blinded, placebo control study. Forty patients, 9–18 yr age, were randomized either (initial dose 10 mg/kg infusion 1 mg · kg−1 h−1) or...
Study Objectives: Obstructive sleep apnea (OSA) is commonly treated with adenotonsillectomy (AT), bringing risk of perioperative respiratory adverse events (PRAEs).We aimed to concurrently identify clinical and polysomnographic predictors PRAEs in children undergoing AT.Methods: Retrospective study AT at a tertiary-care pediatric hospital, prior in-hospital polysomnography, January 2010 December 2016.PRAEs included those requiring oxygen, jaw thrust, positive airway pressure, or mechanical...
Pediatric adenotonsillectomy (A&T) is associated with prolonged pain and functional limitation. Celecoxib an effective analgesic in adult surgery patients; however, its efficacy on recovery pediatric A&T patients unknown.During 2009-2012, children (age 2-18 yr) scheduled for elective were enrolled a single-centre double-blind randomized controlled trial. Study participants received either oral placebo or celecoxib 6 mg·kg(-1) preoperatively, followed by 3 twice daily five doses. The primary...
Background Champlain BASE™ (Building Access to Specialists through eConsultation) is a web-based asynchronous electronic communication service that allows primary-care- practitioners (PCPs) submit “elective” clinical questions specialist. For adults, PCPs have reported improved access and timeliness specialist advice, averted face-to-face referrals in up 40% of cases high provider satisfaction. Objective To determine whether the expansion eConsult pediatric setting would result similar...
Central adiposity and large neck circumference are associated with obstructive sleep apnea (OSA) in adults but have not been evaluated children as predictors of OSA. Study objectives were to determine whether (1) anthropometric measures including neck-to-waist ratio OSA older children; (2) body fat distribution, measured by ratio, is predictive overweight/obese children.Cross-sectional study involving 7-18 years scheduled undergo polysomnography at a tertiary care children's hospital. was...
A massive hemorrhage protocol (MHP) enables rapid delivery of blood components in a patient who is exsanguinating pending definitive control, but there variability MHP implementation rates, content and compliance owing to challenges presented by infrequent activation, variable team performance acuity. The goal this project was identify the key evidence-based principles quality indicators required develop standardized regional MHP.A modified Delphi consensus technique performed spring summer...
Abstract Background: Accurate and reliable evaluation of cardiac index (CI) in critically ill pediatric patients can optimize their management. Although validated, noninvasive ultrasound measurement techniques have been previously shown to be unreliable because observer variability. Objective: To confirm intra‐ inter‐observer reliability when using the USCOM ® healthy anesthetized children. Methods: Prospective observational study at Children’s Hospital Eastern Ontario, Ottawa, included...
Rationale Large neck circumference (NC) is associated with obstructive sleep apnea (OSA) in adults, especially males. Since NC changes age and sex, a lack of reference ranges makes size difficult to assess as screening tool children. Methods Using population-based dataset 1,913 children, we developed for by sex children aged 6–17 years. In this study, collected data on 245 years presenting the Children's Hospital Eastern Ontario polysomnography. The association between > 95th percentile OSA...
Electronic consultations (eConsult) allow for communication between primary care providers and specialists in an asynchronous manner. This study examined provider satisfaction, topics of interest, efficiency eConsult pediatric hematology/oncology Ottawa, Canada.We conducted a cross-sectional assessment all cases directed to using the Champlain BASE (Building Access Specialists through eConsultation) service from June 1, 2014 May 31, 2016.There were 1064 eConsults pediatrics during timeperiod...
Summary Background The accurate measurement of core temperature is an essential aspect intraoperative management in children. Invasive sites are but carry some health risks and cannot be used certain patients. An form noninvasive thermometry therefore needed. Our aim was to develop, subsequently validate, separate models for estimating using different skin temperatures with individualized correction factor. Methods Forty‐eight pediatric patients (0–36 months) undergoing elective surgery were...
ABSTRACT Objectives Primary care practitioners (PCPs) report that using the Champlain BASE™ eConsult service (eConsult) averts one-third of face-to-face (FTF) specialist referrals, however, there are concerns about duplication services and adverse patient outcomes. Following an eConsult, we evaluated healthcare utilization associated treatment costs. Methods Retrospective cohort study (2014 to 2018) patients (<18 years old) for whom visit averted a FTF referral. Patients were linked...
Obstructive sleep-disordered breathing is commonly treated with adenotonsillectomy. Our study objective was to describe perioperative opioid dosing in children a range of medical complexity evaluated for obstructive undergoing adenotonsillectomy and investigate its association postoperative respiratory adverse events (PRAEs).A retrospective chart review who underwent had preoperative polysomnography performed conducted. PRAEs included requiring oxygen, jaw thrust, positive airway pressure,...
The goal of this study was to identify cerebral microemboli during scoliosis surgery and their potential relationship with visual alterations. Transcranial Doppler identified high-intensity transient signals (HITS) in both middle arteries, ophthalmologic examination assessed effects on the system. Thirteen children (age 13-17 years) undergoing for or kyphosis spine curvature >45 degrees were studied. HITS 92%. Eleven patients had a total count <15 HITS, but remaining two unexpectedly high...
Abstract Introduction Solutions like crowd screening and machine learning can assist systematic reviewers with heavy burdens but require training sets containing a mix of eligible ineligible studies. This study explores using PubMed's Best Match algorithm to create small at least five relevant Methods Six reviews were examined retrospectively. MEDLINE searches converted run in PubMed. The ranking included studies was studied under both Most Recent sort conditions. Results Retrieval sizes for...
The first-line treatment of obstructive sleep apnea syndrome in children is adenotonsillectomy, but this may result perioperative respiratory adverse events (PRAEs). primary aim study to examine whether the McGill oximetry score (MOS) and other polysomnography parameters can predict major PRAEs following adenotonsillectomy. We secondarily evaluated MOS interrater reliability correlation with parameters.This retrospective included all aged 0-18 years who underwent preoperative between June...