A5047496478- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Neuroscience and Neuropharmacology Research
- Metabolism and Genetic Disorders
- Long-Term Effects of COVID-19
- EEG and Brain-Computer Interfaces
- Glioma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Neonatal and fetal brain pathology
- Traumatic Brain Injury and Neurovascular Disturbances
- Psychosomatic Disorders and Their Treatments
- Advanced Neuroimaging Techniques and Applications
- COVID-19 and Mental Health
- Mental Health and Psychiatry
- RNA modifications and cancer
- Acute Ischemic Stroke Management
- Vagus Nerve Stimulation Research
- Peripheral Neuropathies and Disorders
- Tryptophan and brain disorders
- Neonatal Respiratory Health Research
- Neurological Complications and Syndromes
- Neuroblastoma Research and Treatments
- Circadian rhythm and melatonin
- Herpesvirus Infections and Treatments
- Cerebrovascular and genetic disorders
Texas A&M Health Science Center
2011-2024
Texas A&M University
2014-2024
St. Joseph Health System
2023-2024
Bryan College
2023
Baylor Scott & White Health
2010-2019
Temple College
2018-2019
Baylor University
2018
Baylor Scott & White Medical Center - Temple
2018
Scott & White Memorial Hospital
2011-2016
Neuroscience Institute
2014
BackgroundGlioblastoma multiforme (GBM) is a fatal disease without effective therapy. Identification of new biomarkers for prognosis would enable more rational selections strategies to cure patients with GBM and prevent relapse.MethodsSeven datasets derived from using microarray or next generation sequencing in R2 online database (http://r2.amc.nl) were extracted then analyzed JMP software. The survival distribution was calculated according the Kaplan-Meier method significance determined...
The aim of this study is to illuminate a novel therapeutic approach by identifying functional binding target salinomycin, an emerging anticancer stem cell (CSC) agent, and help dissect the underlying action mechanisms. By utilizing integrated strategies, we identify that nucleolin (NCL) likely salinomycin-binding critical regulator involved in human neuroblastoma (NB) CSC activity. Salinomycin markedly suppresses NB CD34 expression reduces CD34+ population NCL-dependent manner via disruption...
To assess the efficacy and safety of eslicarbazepine acetate (ESL) monotherapy.This post hoc pooled analysis 2 randomized double-blind studies (093-045 -046) included adults with partial-onset seizures medically uncontrolled by 1 or antiepileptic drugs (AEDs). Following baseline period (8 weeks), eligible patients were 2:1 to receive ESL 1,600 mg 1,200 once daily for 18 weeks; primary endpoint was study exit meeting predefined criteria (signifying worsening seizure control). In each study,...
Brugada syndrome, a recognized cause of sudden cardiac death, is due to defect sodium channels. Many pharmotherapeutic agents induce an electrocardiographic (ECG) pattern that can be confused with syndrome in patients who may not have the disease.A 22-year-old Hispanic female presented for emergency evaluation ataxia and alterations consciousness. Her medical history was significant temporal lobe epilepsy, treated lamotrigine, phenyltriazine agent known block neuronal voltage-gated There no...
Vagus Nerve Stimulation (VNS) therapy is widely understood to provide clinically meaningful improvements in seizure control patients with drug-resistant epilepsy, and has been a staple the clinical armamentaria available epileptologists for over 25 years. Despite long history of evidence-based reviews by neurology professional societies, there still evidence practice gap VNS titration dosing that aims maximize benefit. Recent retrospective analyses have strongly argued more consistent...
The neurobehavioral profile of anti-epileptic drugs (AEDs) has been a recurrent research topic in the scientific literature. As pharmacological treatments for epilepsy continue to evolve, there is general consensus that newer AEDs have less detrimental side effects comparison their older counterparts. Among and patients, potential risk changes reported with levetiracetam (LEV). Conversely, limited data exists regarding manifestation this symptomatology subgroup patients brain tumors. current...