A5040226608- Nanoparticles: synthesis and applications
- Electrochemical sensors and biosensors
- Analytical Chemistry and Sensors
- Enzyme Catalysis and Immobilization
- Copper-based nanomaterials and applications
- Laser-Ablation Synthesis of Nanoparticles
- Conducting polymers and applications
- Advanced Nanomaterials in Catalysis
- Analytical Chemistry and Chromatography
- Enzyme Production and Characterization
- Heat Transfer Mechanisms
- Medicinal Plants and Neuroprotection
- Computational Drug Discovery Methods
- Advanced Combustion Engine Technologies
- Microbial Metabolic Engineering and Bioproduction
- Polyamine Metabolism and Applications
- Cholinesterase and Neurodegenerative Diseases
- Catalytic Processes in Materials Science
- Nanopore and Nanochannel Transport Studies
- Biodiesel Production and Applications
- Nanofluid Flow and Heat Transfer
- Lipid Membrane Structure and Behavior
- Alzheimer's disease research and treatments
- Phosphodiesterase function and regulation
- Tea Polyphenols and Effects
Yıldız Technical University
2015-2025
University of California, Los Angeles
2012
Alzheimer's disease is a devastating cureless neurodegenerative disorder affecting >35 million people worldwide. The caused by toxic oligomers and aggregates of amyloid β protein the microtubule-associated tau. Recently, Lys-specific molecular tweezer CLR01 has been shown to inhibit aggregation toxicity multiple amyloidogenic proteins, including tau, disrupting key interactions involved in assembly process. Following up on these encouraging findings, here, we asked whether could protect...
Palladium, the building block of white gold, has been found to exhibit extraordinary properties in nanotechnological products produced recent years. The most prominent feature palladium is adsorbing and storing high levels hydrogen. Therefore, demand for world increased excessively 2000s. In present study, nanoparticles (PdNPs) were biosynthesized by extract Diospyros kaki leaves as bio-stimulator. D. kaki, also called persimmon, was collected a local area Istanbul Turkey. PdNP formation...
Copper oxide nanoparticles (CuONPs) are used in many fields from electronics to medicine due their multifunctionality, and therefore, production with environmentally friendly methods is a current issue. In this study, biofabricated CuONPs were obtained by using the leaf extract of Acer palmatum plant originating Far East enlighten characteristics novel differentiating those existing literature. Multifunctional nature was evaluated antibacterial, antifungal, decolorative applications also...
Zinc oxide and gold nanoparticles (ZnONPs AuNPs) are biomimetically synthesized using Echinacea angustifolia flower extract their structure biological activities reported. In this process, the dried flowers extracts reduced zinc metal from precursor nitrate hexahydrate [Zn(NO3)2.4H2O] stabilized within 6 h. Gold were in 10 min by addition of hydrogen tetracholoroaureate (III) hydrate to extract. Nanoparticles characterized through UV–vis, FTIR SEM. The synthesis ZnONPs AuNPs analyzed...
Improvement of the thermal properties coolants used in automobile radiators increases cooling performance engine. Metallic nanoparticle additives generally improve coolant. In this study, heat transfer characteristics a nanofluid prepared with bimetallic (CuO–ZnO) for automotive were experimentally investigated. Experiments made four different fluids under constant heating power. These are water-bimetal mixture 0.1%, 0.2% and 0.3% particulate additives. UA values exchanger calculated using...
Aim: A novel all solid-state contact PVC-membrane beryllium-selective electrode based on 4-hydroxybenzo-15-crown-5 ether as an ionophore is described. Results: The best performance was obtained with a membrane composition of 4% ionophore, 67% dioctyl sebacate (DOS), 28% poly(vinyl chloride) (PVC), and 1% potassium tetrakis (p-chloro)phenylborate (KTClPB) (w/w). PVCmembrane together Ag/AgCl reference exhibited sub-Nernstian response slope 22±1 mV/decade to beryllium ions from 1.0x10-6...
Abstract Copper oxide nanoparticles (CuONPs) were phytosynthesized by Laurus nobilis leaf extract, which was used as a reducing and capping agent. UV‐vis spectroscopy applied, the spectrum of CuONPs gave peak around 300 325 nm. An intense Fourier transform infrared between 4000 500 cm −1 wavelengths exhibited exterior functional groups CuONPs. The results scanning electron microscopy transmission revealed that green synthesized spherical in shape with sizes 90 250 Antibacterial activity...
Abstract Horseradish peroxidase (HRP) characteristics were improved by two techniques, Na-alginate entrapment and glutaraldehyde crosslinking prior to alginate entrapment, in order enhance the stability, functionality removal of dyes waste water. Free, entrapped crosslinked-entrapped enzymes compared activity assays, which indicated optimum temperature is 25 °C pH 4.0–5.0. Kinetics results showed that increased Vmax did not cause any significant decrease Km. The thermal resistance free...
This paper describes the formulation of archaeosomes and evaluation their abilities to facilitate in vitro DNA delivery. Lipids H.hispanica 2TK2 strain were used archaeosome formation, which is formulated by mixing lipids with plasmid encoding green fluorescent protein (GFP) or β-galactosidase (β-gal). Archaeosome/pDNA formation unbound monitored agarose gel electrophoresis. The formulations visualized AFM TEM. zeta potential analysis showed be electronegative. composition dose for transient...
The ability of Archaea to adapt their membrane lipid compositions extreme environments has brought in archaeosomes into consideration for the development drug delivery systems overcoming physical, biological blockades that body exhibits against therapies. In this study, we prepared unilamellar archaeosomes, from polar fraction extracted Haloarcula 2 TK strain, and explored its potential as a vehicle. Rifampicin isoniazid which are conventional drugs tuberculosis medication were loaded...
Abstract A strain of Haloarcula hispanica isolated from Tuzkoy salt mine, Turkey exhibited extracellular lipolytic activity. Important parameters such as carbon sources and concentration for lipase production were investigated. Optimal conditions the enzyme 2TK2 determined. It was observed that activity stimulated by some sources. The high acitivity values obtained in presence 2% (v/v) walnut oil (6.16 U/ml), 1% fish (5.07 olive (4.52 U/ml) (w/v) stearic acid (4.88 at 4M NaCl concentration....
A microliter dead-volume flow-through cell as a potentiometric detector is described in this article for sensitive, selective and simultaneous detection of common monovalent anions cations single column ion chromatography the first time. The consisted less anion- cation-selective composite membrane electrodes together with solid-state matrix reference electrode. separation sensitive sodium (Na+), potassium (K+), ammonium (NH4+), chloride (Cl−) nitrate (NO3−) run was achieved by using 98% 1.5...
This study reports a novel precursor for the ecofriendly and low cost biosynthesis of economically important titanium dioxide nanoparticles (TiO2NPs) using Salvia officinalis. TiO(OH)2 was used with aqueous solution officinalis leaf extract. The evaluation TiO2NPs were achieved by UV–vis, XRD, SEM AFM studies. results obtained spectrophotometrically reassuring as pointing an expeditious surface plasmon resonance at 405 nm. formation nano-crystalline nature evaluated XRD spectrum reflections...
Gene therapy is used for developing strategies the treatment of genetic diseases and it a promising technique people with incurable diseases.A successful gene includes
In this study, a micro-sized lactate sensitive biosensor based on polyvinylchloride, quinhydrone and graphite composite pH sensing platform was developed. Lactate oxidase immobilized the layer as biorecognition element. Transformation reaction of to pyruvate hydrogen peroxide basis system. reaction, undergoes give hydronium ions into solution, membrane detects adjunct potentiometrically. The surface matrice first examined for electrochemical elucidation by using cyclic voltammetry impedance...
Ultrasonic irradiation is considered an effective way to increase mass transfer between immiscible liquid–liquid phases in a heterogeneous system leading faster transesterification and higher yield saving excess methanol catalyst. In this study, the of hazelnut oil with ethanol was performed presence potassium hydroxide or sodium methoxide as catalyst using two types ultrasonic probe (20 kHz, 200 W) bath (35 400 W); conventional production method also used. The reaction time, alcohol:oil...
Non-covalent complexes of urease/polyethylene glycol (PEG)-aldehyde were synthesized using regular molar ratios urease and PEG-aldehyde at room temperature. The physical properties the non-covalent analyzed in order to investigate impact coupling ratio, temperature, pH, storage stability, thermal stability. Urease activity was by UV-Vis spectrophotometer 630 nm. results showed that strongest resistance obtained nU/nPEG:1/1 (mg/mL) complex within all tested. enzymatic doubled free enzyme....