A5079275543- Liver Disease Diagnosis and Treatment
- Gout, Hyperuricemia, Uric Acid
- Alcohol Consumption and Health Effects
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heart Rate Variability and Autonomic Control
- Heavy Metal Exposure and Toxicity
- Case Reports on Hematomas
- Blood Pressure and Hypertension Studies
- Parathyroid Disorders and Treatments
- Cardiovascular Function and Risk Factors
- Diabetes Treatment and Management
- Peripheral Artery Disease Management
- Heavy metals in environment
- Diabetes Management and Research
- Venous Thromboembolism Diagnosis and Management
- Inflammatory Biomarkers in Disease Prognosis
- Cardiovascular Disease and Adiposity
- Trace Elements in Health
- Aortic aneurysm repair treatments
- Cardiac electrophysiology and arrhythmias
- Adipokines, Inflammation, and Metabolic Diseases
- Sodium Intake and Health
- Environmental Justice and Health Disparities
- Chronic Kidney Disease and Diabetes
- Obesity and Health Practices
Kaohsiung Medical University
2018-2025
Kaohsiung Municipal Hsiao-Kang Hospital
2021-2025
Kaohsiung Medical University Chung-Ho Memorial Hospital
2018-2025
Weatherford College
2022
Hyperuricemia has been linked with the development of diabetes, gout, kidney, and cardiovascular diseases. Although obesity is associated hyperuricemia, data on sex differences in this association are scarce. Therefore, study was conducted to explore correlations among various indices hyperuricemia Taiwan. Data were obtained from Taiwan Biobank included 122,067 participants. After excluding 179 participants missing data, remaining 121,888 (men: 43,790; women: 78,098) enrolled. The prevalence...
Gut dysbiosis can induce chronic inflammation and contribute to atherosclerosis vascular calcification. The aortic arch calcification (AoAC) score is a simple, noninvasive, semiquantitative assessment tool evaluate on chest radiographs. Few studies have discussed the relationship between gut microbiota AoAC. Therefore, this study aimed compare composition patients with diseases high or low AoAC scores. A total of 186 (118 males 68 females) diseases, including diabetes mellitus (80.6%),...
A lower blood pressure threshold (≥130/80 mmHg) to define hypertension has been proposed in several guidelines. This study assessed the relationship between hyperuricemia and incident hypertension, examining serum uric acid (SUA) cut-offs using both traditional new definitions a large Taiwanese cohort. observational cohort enrolled 26 973 participants from Taiwan Biobank (TWB), followed for median of 4 years. Regarding definition (140/90 mmHg), (odds ratio [OR], 1.297), quartile 3 SUA (OR,...
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have a variety of cardiovascular and renoprotective effects been developed as novel agents for the treatment heart failure. However, beneficial mechanisms SGLT2i on cardiac tissue need to be investigated further. In this study, we established mouse model acute myocardial infarction (AMI) using coronary artery constriction surgery role dapagliflozin (DAPA) in protecting cardiomyocytes from hypoxic injury induced by AMI. vitro experiments were...
Background Obesity is a major risk factor for diabetes mellitus (DM), which in turn cardiovascular diseases such as coronary artery disease and stroke. As few studies have investigated sex differences the association between obesity incidence of DM, aim this longitudinal study was to explore issue large group Taiwanese participants. Methods A total 24,346 participants were enrolled study, whom 8,334 (mean age, 50.6 ± 11.0 years) male 16,012 50.5 10.1 female. The following obesity-related...
Previous studies have shown links between heavy metals and many health issues. However, data on the association mortality in general population are still limited. Therefore, aim of this study was to investigate relationship overall population. We enrolled 2497 participants (1001 males 1496 females) living southern Taiwan, measured levels seven metals: lead (Pb) blood cadmium (Cd), nickel (Ni), copper (Cu), chromium (Cr), manganese (Mn) arsenic (As) urine. The median follow-up period 41.8...
The prevalence rate of hyperuricemia remains high in Taiwan, at 21.6% men and 9.57% women. Both metabolic syndrome (MetS) can cause many complications; however, few studies have evaluated the correlation between MetS hyperuricemia. Therefore, this observational cohort study, we explored associations its components new-onset Of 27,033 individuals Taiwan Biobank who had complete follow-up data, excluded those with baseline (n = 4871), gout 1043), no data on uric acid 18), 71). remaining 21,030...
Dyslipidemia is an important risk factor for hypertension and strongly associated with elevated of cardiovascular diseases including atherosclerosis stroke. In this study, we investigated correlations between lipid profiles, triglycerides, total cholesterol (Chol), high-and low-density lipoprotein (HDL-C/LDL-C), Chol/HDL-C, baseline incident hypertension. A 26,965 subjects 4 years follow-up data were enrolled from the Taiwan Biobank. cross-sectional cohort, associations prevalence profiles...
The global prevalence and incidence of chronic kidney disease (CKD) continue to increase. Whether hyperuricemia is an independent risk factor for renal progression whether there are sex differences in the relationships between serum uric acid (UA) a decline function unclear. Therefore, this longitudinal study, we aimed explore these large cohort around 27,000 Taiwanese participants Taiwan Biobank (TWB), also identify UA cutoff levels men women predict new-onset CKD. A total 26,942 with...
The incidence of chronic kidney disease (CKD) is increasing worldwide; however, the association between CKD and anemia hyperuricemia has yet to be clarified. In addition, whether only influence renal damage in combination with other comorbidities or they are direct causative factors also controversial. Therefore, aim this longitudinal study was investigate these issues a large Taiwanese cohort. We enrolled 26,631 participants from Taiwan Biobank (TWB) after excluding those at baseline, all...
An elevated white blood cell (WBC) count has been linked to incident diabetes. WBC positively associated with body mass index (BMI), and BMI reported be a strong predictor of future Hence, the association increased subsequent development diabetes may mediated by BMI. This study was designed address this issue. We selected subjects from 104,451 participants enrolled 2012 2018 in Taiwan Biobank. only included those complete data at baseline follow-up without baseline. Finally, 24,514 were...
Left atrial strain can usefully reflect left function. The follow-up periods in previous studies assessing as a survival predictor have been relatively short, and few examined the ability of to predict mortality patients with borderline diastolic This study sought investigate predictive value longer duration. In addition, we also evaluated
The early detection of arteriovenous (AV) access dysfunction is crucial for maintaining the patency vascular access. This study aimed to use deep learning predict AV malfunction necessitating further management.
(1) Background: The autonomic imbalance plays a role in vasovagal syncope (VVS) diagnosed by head-up tilting test (HUT). neuECG is new method of recording skin electrical signals to simultaneously analyze sympathetic nerve activity (SKNA) and electrocardiogram. We hypothesize that SKNA higher subjects with tilt-positive than tilt-negative the surges before syncope. (2) Methods: recorded 41 who received HUT (according "Italian protocol"), including rest, tilt-up, provocation recovery phases....
Hyperuricemia is the chief cause of gout and has been linked with hypertension, cardiovascular renal disease, diabetes metabolic syndrome. Liver highest protein expression xanthine oxidase, main enzyme responsible for uric acid formation, primary site biosynthesis. However, there are few studies that examine association between liver function new-onset hyperuricemia. Hence, using Taiwan Biobank dataset, we aimed to explore capability parameters, including gamma-glutamyl transferase, total...
Abstract Rationale: Infective endocarditis (IE) complicated with obstructive ST elevation myocardial infarction (STEMI) has been reported in the literature and which were mostly related to coronary artery embolism, obstruction, or compression. However, there no case discussing about IE nonobstructive STEMI. Patient concerns: In this report, we report a 38-year-old female suffering from intermittent fever was later diagnosed as IE. Initially antibiotic given mitral valve surgery also arranged...
Patients with end-stage renal disease have a higher risk of cardiovascular morbidity and mortality. In this study, we investigated the predictive ability combination cardiothoracic ratio (CTR) aortic arch calcification (AoAC) for overall mortality in patients receiving hemodialysis. We also evaluated power AoAC CTR clinical outcomes. A total 365 maintenance hemodialysis were included, measured using chest radiography at enrollment. stratified into four groups according to median score three...
Patients with end-stage renal disease have a high prevalence of cardiovascular disease. Chest radiography can be used to assess cardiothoracic ratio (CTR) and aortic arch calcification (AoAC). The aims this longitudinal follow-up study were investigate factors associated changes in CTR AoAC understand whether these are overall mortality hemodialysis (HD) patients. We enrolled 260 patients undergoing HD who had at least two available chest X-rays from 2008 2015. assessed each patient using...
Acute myocardial infarction (AMI) is a critical cardiovascular disease with high morbidity and mortality. Identifying practical parameters for predicting long-term mortality crucial in this patient group. The percentage of mean arterial pressure (%MAP) useful parameter used to assess peripheral artery disease. It can be easily calculated from ankle pulse volume recording. Previous studies have shown that %MAP predictor all-cause specific populations, but its relationship AMI patients unclear.
A functioning arteriovenous (AV) access is essential for hemodialysis efficiency and the quality of life in patients. Blood osteoprotegerin (OPG) soluble receptor activator nuclear factor kappa B ligand (RANKL) have been linked to cardiovascular diseases vascular calcification. This study investigated relationship between blood OPG, RANKL, occurrence AV thrombosis.
Acute limb ischemia (ALI) is a medical emergency necessitating immediate action to avert irreversible tissue harm and loss. Rotarex mechanical thrombectomy (RMT) has become an efficient treatment alternative for ALI. However, there lack of data on RMT in Taiwan.