A5070286149- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal complexes synthesis and properties
- Magnetism in coordination complexes
- Crystal structures of chemical compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Lanthanide and Transition Metal Complexes
- Crystallography and molecular interactions
- Organic and Molecular Conductors Research
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Organometallic Compounds Synthesis and Characterization
- Inorganic Chemistry and Materials
- Cancer therapeutics and mechanisms
- Electron Spin Resonance Studies
- Organometallic Complex Synthesis and Catalysis
- Synthesis and Reactivity of Heterocycles
- Bioactive Compounds and Antitumor Agents
- Porphyrin and Phthalocyanine Chemistry
- Multicomponent Synthesis of Heterocycles
- Synthesis of Organic Compounds
- Inorganic Fluorides and Related Compounds
- Advanced Condensed Matter Physics
- Protein Interaction Studies and Fluorescence Analysis
- Nonlinear Optical Materials Research
University of Pavol Jozef Šafárik
2016-2025
Institute of Chemistry of the Slovak Academy of Sciences
2012-2023
Technical University of Košice
2017-2021
Institute of Chemistry
2017-2020
Institute of Molecular Biology and Biophysics
2017
University of Veterinary Medicine in Košice
2017
University of Cologne
2010
RWTH Aachen University
2010
Slovak University of Technology in Bratislava
1995-1999
Pseudooctahedral mononuclear cobat(II) complex [Co(abpt)2(tcm)2] (1), where abpt = 4-amino-3,5-bis(2-pyridyl)-1,2,4-triazole and tcm tricyanomethanide anion, shows field-induced slow relaxation of magnetization with U 86.2 K large axial rhombic single-ion zero-field-splitting parameters, D +48(2) cm–1 E/D 0.27(2) (D +53.7 0.29 from ab initio CASSCF/NEVPT2 calculations), thus presenting a new example magnet transversal magnetic anisotropy.
In this contribution, four new compounds synthesized from 4-hydroxycoumarin and tyramine/octopamine/norepinephrine/3-methoxytyramine are characterized spectroscopically (IR NMR), chromatographically (UHPLC-DAD), structurally at the B3LYP/6-311++G*(d,p) level of theory. The crystal structure 4-hydroxycoumarin-octopamine derivative was solved used as a starting geometry for structural optimization. Along with previously obtained 4-hydroxycoumarin-dopamine derivative, intramolecular...
A series of palladium(II) complexes with derivatives 8‐hydroxyquinoline (HXQ) composition NH2(CH3)2[PdCl2(XQ)] where HXQ is 5‐nitro‐7‐iodo‐8‐hydroxyquinoline (HNIQ) (1a), 5‐nitro‐7‐bromo‐8‐hydroxyquinoline (HNBrQ) (2a), 5‐iodo‐7‐bromo‐8‐hydroxyquinoline (HIBrQ) (3a) and 5‐chloro‐7‐bromo‐8‐hydroxyquinoline (HClBrQ) (4a) was prepared. Upon their dissolution in DMSO, [PdCl(DMSO)(XQ)] (1b‐4b) [Pd(XQ)2] (1c‐4c) were prepared as a consequence ligand exchange. The the elucidated by infrared NMR...
In this work, gallium(III) complex with cloxyquin (5-chloro-8-quinolinol, HClQ) ligands is shown to effectively inhibit proliferation of rhabdomyosarcoma cells, the frequent, aggressive, and poorly treatable cancer children. It offers striking selectivity cells compared noncancerous human fibroblasts. The data reveal that induces ferroptosis in likely due interfering iron metabolism. Importantly, it can kill both bulk stem cells. To best our knowledge, first compound based on metal other...
A series of mononuclear hexacoordinate Co(ii) complexes with the 4-amino-3,5-bis(2-pyridyl)-1,2,4-triazole (abpt) ligand and various linear non-linear pseudohalides, such as NCSe (selenocyanate), N{C(CN)2}2 (1,1,3,3-tetracyano-2-azapropenide, tcap), NO2C(CN)2 (nitrodicyanomethanide, nodcm), C(CN){C(CN)2}2 (1,1,2,3,3-pentacyanopropenide, pcp), NO2NCN (nitrocyanamide, nca), ONC(CN)2 (nitrosodicyanomethanide, ndcm), was prepared. X-ray analyses revealed formation general compositions...
The newly synthesized coumarin derivative with dopamine, 3-(1-((3,4-dihydroxyphenethyl)amino)ethylidene)-chroman-2,4-dione, was completely structurally characterized by X-ray crystallography. It shown that several types of hydrogen bonds are present, which additionally stabilize the structure. compound tested in vitro against different cell lines, healthy human keratinocyte HaCaT, cervical squamous carcinoma SiHa, breast MCF7, and hepatocellular HepG2. Compared to control, new derivate...
Two new complexes, bis-[4-amino-3,5-bis-(pyridin-2-yl)-1,2,4-triazole-κ
The title compound, [Cu(C 2 N 3 ) (C 12 H 8 ], was prepared and its crystal structure solved as a part of our study on synthesis, crystallochemistry properties copper compounds with pseudohalogenide anions. structure, which is formed by discrete molecules, presented. dicyanamide phen ligands are bonded to the Cu atom elongated tetragonal bipyramidal (4+2) coordination geometry, in cis arrangement
Two tetranuclear [Zn4Cl2(ClQ)6]·2DMF (1) and [Zn4Cl2(ClQ)6(H2O)2]·4DMF (2), as well three dinuclear [Zn2(ClQ)3(HClQ)3]I3 (3), [Zn2(dClQ)2(H2O)6(SO4)] (4) [Zn2(dBrQ)2(H2O)6(SO4)] (5), complexes (HClQ = 5-chloro-8-hydroxyquinoline, HdClQ 5,7-dichloro-8-hydroxyquinoline HdBrQ 5,7-dibromo-8-hydroxyquinoline) were prepared possible anticancer or antimicrobial agents characterized by IR spectroscopy, elemental analysis single crystal X-ray structure analysis. The stability of the in solution was...
The crystal structure of [Cu(C12H8N2)2{N(CN)2}][C(CN)3] is formed by discrete [Cu(phen)2{N(CN)2}]+ cations and [C(CN)3]− anions (phen = 1,10-phenanthroline). coordination polyhedron CuII a distorted trigonal bipyramid with CuN5 chromophore.