A5032294361- Infectious Diseases and Tuberculosis
- Circular RNAs in diseases
- Liver Disease Diagnosis and Treatment
- Streptococcal Infections and Treatments
- Hepatitis B Virus Studies
- Orthopedic Infections and Treatments
- Otolaryngology and Infectious Diseases
- Lysosomal Storage Disorders Research
- Genital Health and Disease
- Urinary Tract Infections Management
- Hidradenitis Suppurativa and Treatments
- Biomedical Research and Pathophysiology
- RNA Research and Splicing
- Infectious Diseases and Mycology
- Cancer-related molecular mechanisms research
- Chemotherapy-related skin toxicity
- Cytomegalovirus and herpesvirus research
- Metabolism and Genetic Disorders
- Pulmonary Hypertension Research and Treatments
- Legionella and Acanthamoeba research
- Mycobacterium research and diagnosis
- Reproductive tract infections research
- Child Nutrition and Feeding Issues
- Pneumocystis jirovecii pneumonia detection and treatment
- Tuberculosis Research and Epidemiology
Hangzhou Medical College
2021-2024
Zhejiang Provincial People's Hospital
2021-2024
Bengbu Medical College
2022
Nantong University
2019
Affiliated Hospital of Nantong University
2019
Abstract Background and aim In China, hepatorenal syndrome is a serious complication in the decompensated stage of hepatitis B cirrhosis, which requires early clinical intervention, so diagnosis crucial. This study establishes new predictive model based on serum biomarkers for syndrome. Methods Patients with cirrhosis who met inclusion exclusion criteria were retrospectively enrolled. randomly assigned to training dataset validation at 7:3 ratio. Univariate multivariate logistic regression...
Abstract Background Psoas abscess (PA) is an uncommon disease that has been increasingly reported in the recent years. We reviewed patients with PA and analyzed their clinical characteristics to improve our understanding of this rare disorder. Methods retrospectively presentations, microbiology, outcomes between 2011 2022 at Zhejiang Provincial People’s Hospital China. Results There were 40 adult identified discharge diagnosis PA. The mean age was 60 years, 67.5% male. Primary symptoms...
Pulmonary arterial hypertension (PAH) is a serious condition. However, prevailing therapeutic strategies are not effective enough to treat PAH. Therefore, finding an therapy clearly warranted. Adipose-derived mesenchymal stem cells (ASCs) and ASCs-derived exosomes (ASCs-Exos) exert protective effects in PAH, but the underlying mechanism remains unclear. Using coculture of ASCs monocrotaline pyrrole (MCTP)-treated human pulmonary artery endothelial (HPAECs), we demonstrated that increased...
ObjectivesHere, we retrospectively described the diagnosis and treatment of 32 cases diagnosed with Chlamydia psittaci pneumonia during COVID-19 pandemic.MethodsClinical information was collected from all patients. Reverse transcription–PCR ELISAs were conducted for detection using nasal swabs bronchoalveolar lavage fluid (BALF) samples. Metagenomic next-generation sequencing (mNGS) performed identification causative pathogens BALF, peripheral blood sputum End-point PCR to confirm mNGS...
Diffuse large B-cell lymphoma (DLBCL) is a common non-Hodgkin's lymphoma. R-CHOP protocol for long-term chemotherapy DLBCL patients. Long-term can lead to low immunity and increase the risk of opportunistic pathogen infections in immunocompromised patients.We report case coinfection with Pneumocystis jirovecii (P. jirovecii) Legionella pneumophila (L. pneumophila) patient DLBCL. The was 40-year-old female who diagnosed admitted due pulmonary infection. P. L. were detected her bronchoalveolar...
Abstract Background The chronic visceral subtype of acid sphingomyelinase deficiency, commonly known as Niemann Pick disease type B (NPDB), is a relatively rare autosomal recessive genetic disorder that caused by mutations in the SMPD1 gene. NPDB with sea-blue histiocytes (SBH) clinically mimics Budd-Chiari syndrome (BCS), it lacks specific clinical characteristics. This makes its diagnosis difficult. Case presentation Here, we report case SBH was misdiagnosed BCS for three years. A...
Abstract: Nontuberculous mycobacteria infections present mostly pulmonary characteristics. However, the incidence of skin and soft tissue caused by nontuberculous has increased in part due to popularity cosmetic plastic surgery. Here, we report a case Mycobacterium agri infection. The patient underwent one-year course anti-infection therapy. To best our knowledge, this is first previously healthy presenting infection . Clinical personnel should be aware possible causes persistent after...
BACKGROUNDInborn error of bile acid synthesis type 4 is a peroxisomal disease with impaired caused by a-methylacyl-CoA racemase (AMACR) gene mutation.The usually found in children mild to severe liver disease, cholestasis and poor fat-soluble vitamin absorption.At present, there no report inborn errors adults absorption. CASE SUMMARYA 71-year-old man was hospitalized our department for recurrent dysfunction.The clinical manifestations were chronic yellow skin sclera.Serum transaminase,...
Liver cancer is one of the most highly malignant cancers, characterized by easy metastasis and chemoradiotherapy resistance. Emerging evidence indicates that long noncoding RNAs (LncRNAs), including Lnc524369, are involved in initiation, progression, radioresistance, chemoresistance hepatocellular carcinoma (HCC). However, function Lnc524369 remains unclear.To explore HCC.To investigate effect tissue from 41 HCC patients were analyzed using CCK8, migration, invasion assays. YWHAZ (also named...
Abstract Psoas abscess (PA) is an uncommon disease that has been increasingly reported in recent years. We reviewed patients with PA and analysed their clinical characteristics to improve the understanding of this rare disorder. The study retrospectively presentations, microbiology, outcomes between 2011 2021 Zhejiang Provincial People’s Hospital China. There were 35 cases out 23057427 hospitalised adult patients; mean age was 60 years, 65.7% male. Primary symptoms typically nonspecific. In...
Introduction: Pyogenic liver abscess (PLA) is a serious infectious disease of the liver. caused by Fusobacterium nucleatum extremely rare. Here we report first case F. in China. Case Presentation: The was 34-year-old female patient admitted to hospital due high fever. diagnosis confirmed imaging studies and puncture. We finally pathogen as next-generation sequencing (NGS). After targeted anti-infective treatment, recovered discharged. Conclusions: As new microbial detection method, NGS can...
Abstract Background and aim In China, hepatorenal syndrome is a serious complication in the decompensated stage of hepatitis B cirrhosis, which requires early clinical intervention, so diagnosis crucial. This study establishes new predictive model based on serum biomarkers for syndrome. Methods Patients with cirrhosis who met inclusion exclusion criteria were retrospectively enrolled. randomly assigned to training dataset validation at 7:3 ratio. Univariate multivariate logistic regression...