A5060163660- Marine Toxins and Detection Methods
- Marine and coastal ecosystems
- Environmental Toxicology and Ecotoxicology
- Nicotinic Acetylcholine Receptors Study
- Microbial Community Ecology and Physiology
- Toxic Organic Pollutants Impact
- Per- and polyfluoroalkyl substances research
- Animal Ecology and Behavior Studies
- Tuberculosis Research and Epidemiology
- Mass Spectrometry Techniques and Applications
- Forensic Toxicology and Drug Analysis
- Mycobacterium research and diagnosis
- Polyamine Metabolism and Applications
- Salivary Gland Tumors Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Aquaculture Nutrition and Growth
- Traditional Chinese Medicine Analysis
- Meat and Animal Product Quality
- Melamine detection and toxicity
- Protist diversity and phylogeny
- Parasites and Host Interactions
- Genetics, Aging, and Longevity in Model Organisms
- Pesticide Residue Analysis and Safety
- Effects and risks of endocrine disrupting chemicals
- Marine Bivalve and Aquaculture Studies
Chinese Academy of Fishery Sciences
2016-2025
Ministry of Agriculture and Rural Affairs
2019-2025
Ministry of Agriculture
2014-2024
Soochow University
2018-2024
The Fifth People’s Hospital of Suzhou
2020-2024
Fuzhou Pulmonary Hospital of Fujian
2024
Second Affiliated Hospital of Nanjing Medical University
2021-2022
The First People's Hospital of Xiaoshan District, Hangzhou
2022
Renmin Hospital of Wuhan University
2020
Wuhan University
2020
Paralytic shellfish toxins (PSTs) are widely distributed in along the coast of China, causing a serious threat to consumer health; however, there is still lack large-scale systematic investigations and risk assessments. Herein, 641 samples were collected from March November 2020, PSTs’ toxicity was detected via liquid chromatography–tandem mass spectrometry. Furthermore, contamination status potential dietary risks PSTs discussed. 241 with detection rate 37.60%. The average PST toxicities...
Perfluorinated alkyl substances (PFASs) are emerging persistent organic pollutants, which pose a threat to human health primarily by dietary exposure, especially through seafood. Bohai Sea (a semi-closed sea located north of China) is an important shellfish aquaculture area that possibly highly-polluted with PFASs. In this study, we first evaluated contamination PFASs in total 230 samples marine from the Sea. Samples included five species, collected spots distributed around were analyzed...
To investigate the prevalence of lipophilic marine biotoxins in shellfish from Chinese market, we used hydrophilic interaction liquid chromatography-tandem mass spectrometry (LC-MS/MS) to measure levels okadaic acid (OA), azaspiracid (AZA1), pectenotoxin (PTX2), gymnodimine (GYM), and spirolide (SPX1). We collected analyzed 291 samples main production sites along a wide latitudinal transect coastline December 2008 2009. Results revealed patchy distribution five toxins highlighted specific...
High-resolution mass spectrometry (HRMS) analysis with the assistance of molecular networking was used to investigate intracellular toxin profiles five Prorocentrum lima (P. lima) strains sampled from north Yellow Sea and South China Sea. Mice were as a model species for testing acute toxicity okadaic acid (OA) dinophysistoxins (DTXs) in free esterified states. Results showed that OA DTX1 derivatives detected all P. samples, accounting 55%–96% total toxins strains. A 24 esters 1 stereoisomer...
Abstract Background sCD25 is an important immune molecule for T cell regulation. Tracking the detection of plasma plays role in evaluation function, progression, and prognosis tuberculosis (TB) patients. This study analyzed association levels with clinical, laboratory, CT imaging characteristics, clinical outcome TB Methods The data 303 patients treated Fifth People’s Hospital Suzhou from October 2019 to January 2022 were retrospectively analyzed. detected by ELISA. According cut-off...
ObjectivesHere, we retrospectively described the diagnosis and treatment of 32 cases diagnosed with Chlamydia psittaci pneumonia during COVID-19 pandemic.MethodsClinical information was collected from all patients. Reverse transcription–PCR ELISAs were conducted for detection using nasal swabs bronchoalveolar lavage fluid (BALF) samples. Metagenomic next-generation sequencing (mNGS) performed identification causative pathogens BALF, peripheral blood sputum End-point PCR to confirm mNGS...
The contamination of 2,2',4,4'-Tetrabrmodiphenyl ether (BDE-47) and perfluorooctanoic acid (PFOA) has drawn a worldwide attention over the risks in ecological food safety. In this work, blue mussel (Mytilus galloprpvincialis) was employed to investigate combined effects BDE-47 (10 ng mL-1) PFOA (100 on tissue distribution, accumulation, elimination, toxicity. Results suggested that accumulated mostly digestive gland, followed by gills gonad, M. galloprovincialis displayed higher accumulation...
Early detection of toxin contamination in shellfish (i.e., prior to harvest) would be considerable advantage fish farmers, researchers and food safety administrators. In 2004, a solid-phase adsorption tracking (SPATT) technique was developed study algal toxins New Zealand harvesting areas. subsequent years, the basic idea have been further developed. Using SPATT method, an investigation into diarrhetic (DSTs) conducted over 10.5-month period 2012 farming areas Lingshan Bay (Yellow Sea,...
The cause of some patients with negative RT-PCR results experienced turn-positive after treatment remains unclear. In addition, understanding the correlation between changes in clinical data course COVID-19 and outcomes is great importance determining prognosis COVID-19. To perform analysis effective screening factors related to outcome Clinical data, including manifestations, laboratory tests, radiography results, methods outcomes, were retrospectively collected analyzed from January March...
Harmful algal blooms in Chinese waters have caused serious domoic acid (DA) contamination shellfish. Although shellfish are at particular risk of dietary exposure to DA, there been no systematic DA assessments coastal waters. A total 451 samples were collected from March November 2020. The presence and four its isomers detected using liquid chromatography-tandem mass spectrometry. spatial-temporal distribution occurrence potential health risks examined. was 198 (43.90%), with a maximum level...
Paralytic shellfish toxins (PSTs) are widely distributed neurotoxins, and the PST metabolic detoxification mechanism in bivalves has received increasing attention. To reveal effect of phase I (cytochrome P450)-II (GST)-III (ABC transport) systems on metabolism Azumapecten farreri, this study amplified stress target using rifampicin, dl-α-tocopherol, colchicine; measured levels; conducted transcriptomic analyses. The highest toxin content reached 1623.48 μg STX eq/kg hepatopancreas only 8.8%...
The relationship between vitamin D and allergic rhinitis (AR) remains unclear. present study investigated their association by examining serum 25-hydroxyvitamin (25(OH)D) levels, blood eosinophils, the expression of receptors (VDR) on nasal mucosa in patients with AR.A total 32 persistent AR 25 controls were enrolled this study. Serum 25(OH)D levels detected enzyme-linked immunosorbent assay, eosinophils peripheral examined an automated hematology system, while VDR inferior turbinate was...