A5007855596- Animal testing and alternatives
- Immunotoxicology and immune responses
- Fuel Cells and Related Materials
- Retinal Development and Disorders
- Electrocatalysts for Energy Conversion
- Microbial infections and disease research
- Carcinogens and Genotoxicity Assessment
- Neuroscience and Neuropharmacology Research
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Herpesvirus Infections and Treatments
- Mycobacterium research and diagnosis
- Bacteriophages and microbial interactions
- Retinal Diseases and Treatments
- Advancements in Solid Oxide Fuel Cells
- Retinal and Optic Conditions
- Viral Infections and Immunology Research
- Asphalt Pavement Performance Evaluation
- Corneal surgery and disorders
- Hybrid Renewable Energy Systems
- Infectious Diseases and Mycology
- Agricultural Systems and Practices
Dr. D. Y. Patil Medical College, Hospital and Research Centre
2022-2024
Rajasthan Dental College and Hospital
2011-2024
Lupin Pharmaceuticals (India)
2020-2024
Dr. D.Y. Patil Vidyapeeth, Pune
2024
LabCorp (United States)
2022-2024
Indian Institute of Technology Roorkee
2021-2024
Baba Raghav Das Medical College
2024
Regional Medical Research Centre
2024
Chhattisgarh Swami Vivekanand Technical University
2023
Indian Oil Corporation (India)
2011-2022
Morphological changes in the lungs of macaques induced by several different LRRK2 inhibitors are reversible and do not lead to lung deficits.
An exploratory survey was undertaken to understand sheep production system, breeding practices and selection criteria for Ethiopian Menz Afar breeds in their home tract as a step towards developing sustainable strategies. The mean flock size 31.6 23.0 area. Half of the pastoralists (Afar) one-fifth smallholder farmers (Menz) do not have ram. Mating predominantly uncontrolled. Higher chance mixing flocks reported most seasons. rams were castrated at 1.7 1.5 years old, respectively. Castrates...
Peripheral nervous system (PNS) toxicity is surveyed inconsistently in nonclinical general studies. These Society of Toxicologic Pathology “best practice” recommendations are designed to ensure consistent, efficient, and effective sampling, processing, evaluation PNS tissues for four different situations encountered during (screening) dedicated neurotoxicity For studies where unknown or not anticipated (situation 1), may be limited one sensorimotor spinal nerve. If somatic suspected 2),...
Applied Genetic Technologies Corporation (AGTC) is developing rAAV2tYF-PR1.7-hCNGB3, a recombinant adeno-associated viral (rAAV) vector expressing the human CNGB3 gene, for treatment of achromatopsia, an inherited retinal disorder characterized by markedly reduced visual acuity, extreme light sensitivity, and absence color discrimination. We report here results study evaluating safety biodistribution rAAV2tYF-PR1.7-hCNGB3 in cynomolgus macaques. Three groups animals (n = 2 males females per...
Applied Genetic Technologies Corporation is developing rAAV2tYF-CB-hRS1, a recombinant adeno-associated virus (rAAV) vector for treatment of X-linked retinoschisis (XLRS), an inherited retinal disease characterized by splitting (schisis) layers causing poor vision. We report here results study evaluating the safety and biodistribution rAAV2tYF-CB-hRS1 in normal cynomolgus macaques. Three groups male animals (n = 6 per group) received intravitreal injection one eye either vehicle, or at two...
Purpose To assess possible correlations between central corneal thickness, tonometry, and ocular dimensions. Patients Methods One hundred seventeen eyes of 117 patients who were not taking any intraocular pressure–lowering medications studied prospectively. Forty-one had hypertension; 13 primary open-angle glaucoma; 10 normal-pressure glaucoma. Twenty-three healthy included. Thirty glaucoma suspects (10 monitored for 20 with intermittent hypertension) included correlation analysis. Tonometry...
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions) Project ( www.toxpath.org/inhand.asp ) is a joint initiative the societies toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP), North America (STP) to develop an internationally accepted nomenclature proliferative nonproliferative lesions in laboratory animals. purpose this publication provide standardized classifying observed most tissues organs dog used nonclinical safety...
Purpose: To compare the Swedish interactive thresholding algorithm (SITA) strategy with full threshold in routine clinical practice. Methods: Using Humphrey visual field analyzer model 750 (Allergan Humphrey, San Leandro, CA), 108 subjects were tested 24–2 SITA (version A9) and strategies. Test results compared for time taken reliability on basis of seven criteria abnormality. Results: The required average 48.8% less than strategy. Patient parameters somewhat better SITA. There was a strong...
Observations have been made on motor conduction velocity in the tibial nerve of rats given 35% myoinositol diet. Comparison between values before and with up to nine weeks dosing revealed no alteration velocity. In such animals, free content sciatic was increased; there detectable lipid inositol concentration. a second series experiments, streptozotocin-induced diabetes compared diabetic animals 1% supplementary dietary myoinositol, control group nondiabetic rats. Conduction reduced but...
One of the principal challenges facing a toxicologic pathologist is to determine and differentiate true adverse effect from nonadverse or an adaptive response. Recent publications Society Toxicologic Pathology (STP) European STP provide guidance for determining communicating adversity in nonclinical toxicology studies. In order forum inform engage discussion on this important topic, continuing education (CE) course was held during 2016 Annual meeting San Diego, CA. The lectures at provided...