A5042797877- Inflammatory Bowel Disease
- Congenital Heart Disease Studies
- Microscopic Colitis
- Autoimmune and Inflammatory Disorders Research
- Cardiovascular Function and Risk Factors
- Muscle Physiology and Disorders
- Adolescent and Pediatric Healthcare
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Pharmaceutical studies and practices
- Eosinophilic Esophagitis
- Cardiac Structural Anomalies and Repair
- Renal function and acid-base balance
- Pregnancy and Medication Impact
- Healthcare Policy and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
- Tracheal and airway disorders
- Cardiac Arrhythmias and Treatments
- Childhood Cancer Survivors' Quality of Life
- Cardiac pacing and defibrillation studies
- Dysphagia Assessment and Management
- Chronic Disease Management Strategies
- Cardiac electrophysiology and arrhythmias
- Pain Management and Treatment
Cincinnati Children's Hospital Medical Center
2011-2021
Pharmaceutical Product Development (India)
2019
University of North Carolina at Chapel Hill
2014
Cancer Research And Biostatistics
2012-2013
University of Cincinnati Medical Center
2012
Fistula Foundation
2012
Saint Louis University
1999
Stanford Medicine
1985
Unintended variation in the care of patients with Crohn disease (CD) and ulcerative colitis (UC) may prevent achievement optimal outcomes. We sought to improve chronic delivery outcomes for children inflammatory bowel by using network-based quality improvement methods.By a modified Breakthrough Series collaborative structure, 6 ImproveCareNow Network centers tested changes illness collected data monthly. used an interrupted time series design evaluate impact these changes.Data were available...
The purpose of this study was to assess health-related quality life (QoL) in children with Duchenne muscular dystrophy (DMD), including development and field-testing a DMD-specific module integrated the core Pediatric Quality Life Inventory (PedsQL).The PedsQL 4.0 Generic Core DMD Module Scales were completed by 203 families, 200 parents 117 boys DMD. Scores on compared those matched healthy children. Relationships between scores patient characteristics examined.By both parent report child...
Regulatory T cells (Tregs) act by suppressing the activation and effector functions of innate adaptive immune responses. HIV infection impacts Treg proportion phenotype, although discrepant results have been reported depending on patient population way Tregs were characterized. The effects highly active antiretroviral therapy (HAART) frequency not thoroughly documented. We performed a detailed longitudinal analysis phenotype in 11 HIV-infected individuals enrolled single, prospective...
Left ventricular noncompaction (LVNC) describes deep trabeculations in the left (LV) endocardium and a thinned epicardium. LVNC is seen both as primary cardiomyopathy secondary finding other syndromes affecting myocardium such neuromuscular disorders. The objective of this study to define prevalence Duchenne Muscular Dystrophy (DMD) population characterize its relationship global LV function. Cardiac magnetic resonance (CMR) was used assess morphology function 151 subjects: DMD with ejection...
Objectives: To evaluate the knowledge and attitudes of residents attendings in emergency medicine (EM) internal (IM) about HIV. Methods: An electronic anonymous 41-question survey IM EM physicians at University Cincinnati Academic Health Center. Results: The was completed by 232 (71.6%). were more likely to routinely offer HIV testing compared (60.7% vs. 27.8%, P = 0.0009). Overall, there no difference offering sex (32% 35.6%) or versus (33.8% 33.3%). Only 70 (30.9%) aware current CDC...
To examine sex differences in medical therapy and clinical outcomes pediatric patients with inflammatory bowel disease (IBD).We performed a cross-sectional analysis of children Crohn (CD) ulcerative colitis (UC) using data from the ImproveCareNow Network collected between May 2007 2010. Clinical remission, severity, body mass index (BMI) z scores, normal height velocity, medication use were analyzed by age.One thousand four hundred nine included (993 had CD 416 UC). No significant found BMI,...
Background In attempts to detect diseases that may place adolescents at risk for sudden death, some have advocated population‐based screening. Controversy exists over electrocardiography (ECG) screening due the lack of specificity, cost, and detrimental effects false positive or extraneous outcomes. Objectives Analyze relationship between precordial lead voltage on ECG left ventricle (LV) mass by echocardiogram in adolescent athletes. Methods Retrospective cohort analysis a prospectively...
Respiratory infections are associated with clinically significant illness in patients sickle cell disease (SCD). The 2009 H1N1 pandemic was perceived as a threat to this population.We undertook chart review of all SCD followed at our institution identify those confirmed infection. Further and laboratory data collected on affected analyze clinical courses the factors that correlated severity.Approximately half infection were managed successfully an outpatient basis oseltamivir therapy. Among...
Fontan survivors have depressed cardiac index that worsens over time. Serum biomarker measurement is minimally invasive, rapid, widely available, and may be useful for serial monitoring. The purpose of this study was to identify biomarkers correlate with lower in patients. Methods results This a multi-centre case series assessing the correlations between magnetic resonance-derived patients ⩾6 years age biochemical haematopoietic obtained ±12 months from resonance. Medical history values were...
Seasonal and geographic variations of inflammatory bowel disease (IBD) exacerbations have been described in adults, with inconsistent findings. We sought to determine whether activity pediatric-onset IBD is associated a seasonal pattern.We examined children Crohn (CD) ulcerative colitis (UC) using data from the ImproveCareNow Collaborative between December 2008 November 2010. compared proportion patients continuous remission for all recorded visits each season. also distribution physician...
<h3>BACKGROUND:</h3> Sleeping metabolic rate (SMR) is used as a proxy for basal in infants, when measurement while awake not practical. Measuring SMR via indirect calorimetry (IC) can be useful assessing feeding adequacy especially compromised neonates. Standard IC equipment, including hood placed over the head, designed smallest of patients. Our aim was to determine whether nonstandard smaller measures neonates similarly compared with standard large hood. <h3>METHODS:</h3> measured healthy...
Objective: To implement a quality improvement based system to measure and improve data in an observational clinical registry support Learning Healthcare System.Data Source: ImproveCareNow Network registry, which as of September 2019 contained from 314,250 visits 43,305 pediatric Inflammatory Bowel Disease (IBD) patients at 109 participating care centers.Study Design: The impact centers was evaluated using statistical process control methodology. Data measures were defined, performance...
Identifying disease progression through enhanced decision support tools is key to chronic management in cystic fibrosis at both the patient and care center level. Rapid decline lung function relative level norms an important predictor of outcomes. Our objectives were construct utilize center-level classification rapid decliners develop animated dashboard for comparisons within patients over time, multiple centers, or between centers. A functional data analysis technique known as principal...