A5003966891- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Dementia and Cognitive Impairment Research
- Neural and Behavioral Psychology Studies
- Parkinson's Disease Mechanisms and Treatments
- Neuroscience and Neural Engineering
- Neurological disorders and treatments
- Sleep and Wakefulness Research
- Neuroscience and Neuropharmacology Research
- Health, Environment, Cognitive Aging
- Analog and Mixed-Signal Circuit Design
- Alzheimer's disease research and treatments
- Neuroscience of respiration and sleep
- Stress Responses and Cortisol
- Advanced MRI Techniques and Applications
- Photoreceptor and optogenetics research
- Heart Rate Variability and Autonomic Control
- Traumatic Brain Injury Research
- Advanced Neuroimaging Techniques and Applications
- Cognitive Functions and Memory
- Gene Regulatory Network Analysis
- Obstructive Sleep Apnea Research
- Neurobiology of Language and Bilingualism
- Visual perception and processing mechanisms
Dokuz Eylül University
2015-2024
Istanbul Arel University
2023
Trinity College Dublin
2019-2020
Neurosciences Institute
2019
Global Brain Health Institute
2019
Istanbul Kültür University
2012-2016
The aim of the present study was to investigate role beta oscillatory responses upon cognitive load in healthy subjects and with mild impairment (MCI). oscillations stimulation is least studied comparison other frequency bands. included 17 consecutive patients MCI (mean age = 70.8 ± 5.6 years) according Petersen's criteria, age- education-matched normal elderly controls 68.5 5.5 years). experiments used a visual oddball paradigm. EEG recorded at 30 cortical locations. EEG-evoked power,...
Alzheimer's disease (AD) is the leading cause of dementia, accounting for 70% cases worldwide. By 2050, dementia prevalence will have tripled, with most new occurring in low- and middle-income countries. Mild cognitive impairment (MCI) a stage between healthy aging marked by deficits that do not impair daily living. People MCI are at increased risk an average progression rate 39% within 5 years. There urgent need low-cost, accessible objective methods to facilitate early detection....
Event-related oscillations (EROs) reflect cognitive brain dynamics, while sensory-evoked (SEOs) sensory activities. Previous reports from our lab have shown that those with Alzheimer's disease (AD) or mild impairment (MCI) decreased activity and/or coherence in delta, theta, alpha and beta responses. In the current study, we investigated gamma responses visual SEO ERO 15 patients AD age-, gender- education-matched healthy controls. The following parameters were analyzed over...
The present study tested the hypothesis that cortical sources of resting state eyes-closed electroencephalographic (rsEEG) rhythms reveal different abnormalities in neural synchronization groups patients with mild cognitive impairment due to Alzheimer’s disease (ADMCI) and dementia Lewy bodies (DLBMCI) as compared cognitively normal elderly (Nold) subjects. Clinical rsEEG data 30 ADMCI, 23 DLBMCI, Nold subjects were available an international archive. Age, gender, education carefully matched...
Brain oscillatory responses can be used for non-invasive analyses of cortico-cortical connectivity, local neuronal synchronization, and coherence oscillations in many neuropsychiatric conditions including Alzheimer's disease (AD). In the present paper, we examine sensory-evoked event-related gamma coherences elicited by visual stimuli three sub-gamma bands two sub-groups patients with AD (i.e., acetylcholinesterase-inhibitor treated untreated) healthy controls. We studied a total 39 probable...
The aim of this retrospective and exploratory study was that the cortical sources resting state eyes-closed electroencephalographic (rsEEG) rhythms might reveal different abnormalities in neural synchronization groups patients with mild cognitive impairment due to Alzheimer's disease (ADMCI) Parkinson's (PDMCI) as compared healthy subjects. Clinical rsEEG data 75 ADMCI, PDMCI, cognitively normal elderly (Nold) subjects were available an international archive. Age, gender, education carefully...
Objective: The Trail Making Test (TMT) is a widely used neuropsychological tool for assessing executive functions. This study aimed to establish regression-based normative data TMT performance in Turkish population aged 18-80, accounting the effects of age, education, and sex on both basic (TMT A B) derived scores B-A B/A). Method: total 462 participants were recruited, with 409 included final analysis after applying exclusion criteria. Participants completed international version TMT....
Abstract Introduction Hippocampal volume is a core biomarker of Alzheimer's disease (AD). However, its contribution over the standard diagnostic workup unclear. Methods Three hundred fifty‐six patients, under clinical evaluation for cognitive impairment, with suspected AD and Mini–Mental State Examination ≥20, were recruited across 17 European memory clinics. After traditional workup, confidence pathology (DCAD) was estimated by physicians in charge. The latter provided results automated...
Background. Event-related oscillations (ERO) may provide a useful tool for the identification of cognitive deficits in mild impairment (MCI) and Alzheimer's disease (AD). In present study, we investigate peak-to-peak amplitude auditory event-related delta MCI subjects. Method. The study included twenty-two consecutive patients with recruited neurology clinic 21 age- education-matched normal elderly controls. A classical oddball paradigm was used experiments. EEG recorded from<mml:math...
Parkinson's disease (PD) is a neurodegenerative that characterized by loss of dopaminergic neurons in the substantia nigra. Mild Cognitive impairment (MCI) and dementia may come along with disease. New indicators are necessary for detecting patients likely to develop dementia. Electroencephalogram (EEG) Delta responses one essential electrophysiological could show cognitive decline. Many research literature showed an increase delta increased load. Furthermore, were decreased MCI Alzheimer...
Abstract Objective The objective of this study was to investigate the functional changes associated with mild cognitive impairment (MCI) using independent component analysis (ICA) word generation task magnetic resonance imaging (fMRI) and resting‐state fMRI. Methods In 17 patients MCI age education‐matched healthy individuals as control group are investigated. All participants underwent fMRI task‐based while performing task. ICA used identify appropriate components (ICs) their networks. Dice...
Mild cognitive impairment (MCI) is considered as a prodromal stage for Alzheimer's disease (AD) in the majority of cases. Event-related oscillations might be used detection deficits. Our group's earlier results showed diminished delt
Abstract Behavioral studies have shown that the recognition of facial expressions may be impaired in patients with Alzheimer's disease (AD). The identification and a expression might represented by event‐related brain oscillations. present study aims to analyze EEG oscillations determine electrophysiological indicators AD patients. EEGs 30 healthy controls were recorded during their perception three different (angry, happy, neutral). Event‐related power spectrum phase locking analyzed theta...