A5100449105- Postharvest Quality and Shelf Life Management
- Plant Physiology and Cultivation Studies
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Plant Pathogens and Fungal Diseases
- Plant Stress Responses and Tolerance
- GABA and Rice Research
- Fungal Plant Pathogen Control
- Plant-Microbe Interactions and Immunity
- Immune cells in cancer
- Medicinal Plants and Neuroprotection
- Gut microbiota and health
- Phagocytosis and Immune Regulation
- Immunotherapy and Immune Responses
- Plant Genetic and Mutation Studies
- Mycotoxins in Agriculture and Food
- Photosynthetic Processes and Mechanisms
- Immune Cell Function and Interaction
- Plant Disease Management Techniques
- Nanocomposite Films for Food Packaging
- Plant Gene Expression Analysis
- Plant biochemistry and biosynthesis
- RNA Interference and Gene Delivery
- Light effects on plants
- Fungal Biology and Applications
Ningbo University
2015-2024
Xinxiang Medical University
2024
Second Affiliated Hospital of Jilin University
2023-2024
Liaoning Normal University
2023
Tianjin First Center Hospital
2023
Tianjin Medical University
2023
Zhengzhou University
2016-2022
Luoyang Institute of Science and Technology
2021
South China Agricultural University
2013
Background Immunotherapy has achieved remarkable advances via a variety of strategies against tumor cells that evade immune surveillance. As important innate cells, macrophages play roles in maintaining homeostasis, preventing pathogen invasion, resisting and promoting adaptive response. CD47 is found to be overexpressed on act as don’t eat me’ signal, which contributes evasion. Macrophages mediated phagocytosis blockade CD47/SIRPα (signal regulatory protein alpha) interaction was proved...
2-Phenylethanol (2-PE), a common compound found in plants and microorganisms, exhibits broad-spectrum antifungal activity. Using Botrytis cinerea, we demonstrated that 2-PE suppressed mycelium growth vitro strawberry fruit reduced natural disease without adverse effects to quality. caused structural damage mycelia, as shown by scanning transmission electron microscopy. From RNA sequencing analysis significantly upregulated genes for enzymatic nonenzymatic reactive oxygen species (ROS)...
This study aimed to reveal the effects and possible mechanism of terpinen-4-ol, main component tea tree oil (TTO), on disease resistance strawberry fruit. When TTO its components were compared decay development in fruit inoculated with Botrytis cinerea after treatment, treated terpinen-4-ol showed lowest incidence (44.4%) 48 h also smallest lesion diameter during whole storage. indicates that induces highest other components. Untargeted metabolomic analysis treatment strongly activated...
Sucrose metabolism, particularly the decomposition of sucrose by invertase, plays a central role in plant responses to cold stress. Invertase inhibitors (INHs) evolved higher plants as essential regulators metabolism. By limiting invertase activity, INHs keep cellular sugar levels elevated, which provides enhanced protection under Our results showed that expression PpVIN2, only vacuolar (VIN) gene peach fruit sensitive chilling temperatures, increases significantly during storage, while VIN...
Most cancers contain abundant tumor-associated macrophages (TAMs). TAMs usually display a tumor-supportive M2-like phenotype; they promote tumor growth and influence lymphocyte infiltration, leading to immunosuppression. These properties have made an attractive cancer immunotherapy target. One promising immunotherapeutic strategy involves switching the tumor-promoting immune suppressive microenvironment by reprogramming TAMs. However, clinical trials of macrophage yielded unsatisfactory...
Tea tree oil liposomes (TTO-LPs) were prepared using thin film dispersion and orthogonal optimization. TTO solid (TTO-SLPs) then generated from TTO-LPs by spray drying, (2-Hydroxypropyl)-β-Cyclodextrin (HP-β-CD) as a drying protective agent. The physical chemical characteristics of TTO-SLPs determined, their antifungal activities against Monilinia fructicola measured. Finally, applied to peaches test effects on fruit during storage. optimal process parameters for the preparation follows:...
Abstract Background Metastasis is the leading cause of mortality in human cancers, including esophageal squamous cell carcinoma (ESCC). As a pro-inflammatory cytokine, IL-32 was reported to be poor prognostic factor many cancers. However, role ESCC metastasis remains unknown. Methods cells with ectopic expression or knockdown were established and their effects on motility detected. Ultracentrifugation, Transmission electron microscopy Western blot used verify existence extracellular vesicle...
Dendritic cells (DCs) are professional antigen-presenting with antigen recognition molecules on the surface. Clec9a is selectively expressed mouse CD8a+ DCs and CD103+ subsets, which functionally similar to human BDCA3+ DCs. It reported that responsible for cross-presentation of these DC subsets. In present study, by using phage display technique, we discovered a novel peptide WH, can bind Flt3L induced Clec9a+ or over-expressed HEK-293T cells. Furthermore, computer-aided docking model...
This study investigated the anti-fungal properties of Solidago canadensis L essential oil (SCLEO) against Botrytis cinerea in vitro, and its ability to control gray mold maintain quality strawberry fruits. SCLEO exhibited dose-dependent antifungal activity B. profoundly altered mycelial morphology, cellular ultrastructure, membrane permeability as evaluated by scanning electron microscopy, transmission fluorescence microscopy. vapor at 0.1 mL/L maintained higher sensory acceptance reduced...