A5101720007- Hematopoietic Stem Cell Transplantation
- Acute Lymphoblastic Leukemia research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Childhood Cancer Survivors' Quality of Life
- Pleural and Pulmonary Diseases
- Vascular Tumors and Angiosarcomas
- Facial Rejuvenation and Surgery Techniques
- Facial Nerve Paralysis Treatment and Research
- Vascular Malformations and Hemangiomas
- Cardiac tumors and thrombi
- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Metastasis and carcinoma case studies
- Neuroblastoma Research and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Uterine Myomas and Treatments
- Soft tissue tumor case studies
- Pancreatic function and diabetes
- Testicular diseases and treatments
- Tracheal and airway disorders
- Pneumonia and Respiratory Infections
- Parvovirus B19 Infection Studies
- Infectious Diseases and Tuberculosis
- Autoimmune and Inflammatory Disorders Research
- Case Reports on Hematomas
Seoul National University Hospital
2024-2025
Seoul National University Children's Hospital
2020-2025
Google (United States)
2024
New Generation University College
2024
Seoul National University
2000-2024
Catholic University of Daegu
2010-2024
Chung-Ang University Hospital
2023
Jeonju University
2023
Yonsei University
2021-2023
Hankuk University of Foreign Studies
2023
Background: Meniscal deficiency from meniscectomy is a common situation in clinical practices. Regeneration of the deficient meniscal portion, however, still not feasible. Purpose: To develop an injectable hydrogel system consisting fibrin (Fb) and polyethylene oxide (PEO) to estimate its potential for treating segmental defect meniscus rabbit model. Study Design: Controlled laboratory study. Methods: The Fb/PEO was fabricated by extruding 100 mg·mL -1 fibrinogen solution 2,500 U·mL thrombin...
Injectable hydrogel systems are a facile approach to apply the damaged meniscus in minimally invasive way. We herein developed clinically applicable and injectable semi-interpenetrated network (semi-IPN) system based on fibrin (Fb), reinforced with Pluronic F127 (F127) polymethyl methacrylate (PMMA), improve intrinsic weak mechanical properties. Through dual-syringe device system, could form gel state within about 50 s, increment of compressive modulus Fb hydrogels was achieved by adding...
Abstract Traditionally, bone marrow (BM) has been preferred as a source of stem cells (SCs) in pediatric hematopoietic SC transplantation (HSCT); however, the use peripheral blood SCs (PBSC) recently increased. With advancing graft-versus-host disease (GVHD) prophylaxis, whether BM is still better than PB sibling donor HSCT remains controversial. Here, we compared results (BMT) and PBSC (PBSCT) patients with malignant or non-malignant diseases receiving using total 7.5 mg/kg anti-thymocyte...
The purpose of this study was to use CT differentiate anthracofibrosis from endobronchial tuberculosis (TB), both which are major causes benign bronchostenosis.We retrospectively reviewed the clinical and findings 49 patients with 35 TB diagnosed on basis bronchoscopic, microbiologic, pathologic findings. Forty-five 32 had bronchostenosis were enrolled in analysis. Nine (20%) 45 coexistent active (two, TB; six, pulmonary one, pleurisy), 13 (29%) infections other than TB. Two excluded...
Megalencephaly-capillary malformation-polymicrogyria syndrome (MCAP) belongs to a group of conditions called the PIK3CA-related overgrowth spectrum (PROS). The varying phenotypes and low frequencies each somatic mosaic variant make confirmative diagnosis difficult. We present 12 patients who were diagnosed clinically genetically with MCAP. Genomic DNA was extracted mainly from skin affected lesions, also peripheral blood leukocytes buccal epithelial cells, target panel sequencing using...
The purpose of this study is to evaluate the prevalence and clinicoradiologic characteristics pulmonary tuberculosis with lymphatic involvement.A total 126 adults active who underwent CT were enrolled. A retrospective investigation images focused on presence perilymphatic micronodules, as well other features tuberculosis. We selected two groups patients micronodules according distribution (perilymphatic vs centrilobular). compared clinical findings between groups.Fifteen excluded because...
The use of haploidentical related donors (HRDs) is a common alternative donor strategy used when matched sibling or unrelated are not available for hematopoietic stem cell transplantation (HSCT). However, there have been no studies comparing HRD HSCT with post-transplantation cyclophosphamide (PTCy) and (MUD) antithymocyte globulin using similar busulfan-based myeloablative conditioning regimens in pediatric acute leukemia. Here we compared the outcomes children adolescents high-risk...
Bronchiectasis in tuberculosis (TB) is usually considered chronic traction bronchiectasis associated with healed scars. However, can occasionally be seen active TB.To evaluate prevalence, appearance, and changes of TB on computed tomography (CT).A total 391 patients who had undergone CT scans at the time diagnosis were included study. Active was diagnosed when sputum or sample obtained by bronchoalveolar lavage tested positive using an acid-fast bacillus (AFB) smear test, polymerase chain...
Early diagnosis of leptomeningeal carcinomatosis (LMC) is necessary to improve outcomes this formidable disease. However, cerebrospinal fluid (CSF) cytology frequently false negative. We examined whether CSF metabolome profiles can be used differentiate patients with LMC from having a risk for development LMC.A total 10,905 LMIs were evaluated using PCA-DA. The defined Group 2 sensitivity 85% and specificity 91%. After selecting 33 LMIs, including diacetylspermine fibrinogen fragments, the...
Extranodal marginal zone lymphoma is a low-grade B cell that presents with an indolent clinicopathologic nature.Although this tumor can occur in various sites, including the gastrointestinal tract and lungs, it develops spreads extremely rarely along trachea central airway.We report case of extranodal mucosa-associated lymphoid tissue tracheobronchial involvement.An 83-year-old woman presented cough dyspnea.Bronchoscopic evaluation confirmed diffuse, multiple nodular lesions both large...
연구배경: 기관지내시경 시행 시 기관지점막에 탄분침착을 보이는 경우가 종종 있다. 이러한 기관지탄분섬유증은 결핵과 연관이 있다고 여겨지는데 최근 논문들에 의하면 결핵 이외의 만성폐쇄성 폐질환이나 폐렴 등의 다양한 폐질환과 관련이 있음이 보고되어 진다. 방법: 2003년 1월부터 2006년 7월까지 강남성모병원에서 검사를 받은 환자들 중 기관지 탄분침착이 있는 환자들을 대상으로 진료기록지를 통해 후향적 분석을 하였다. 기저질환, 임상소견, 폐기능 검사 및 조직소견, 방사선소견을 분석하였고 비결핵성 기관지탄분섬유증 환자에서 기관지협착이 동반된 경우 스테로이드 투여 그 치료성적을 분석하였다. 결과: 총 74명 환자가 54명(73%)이었다. 이 41명(76%)에서 협착이 동반되었고 13명(24%)은 탄분침착만 보였다. 환자 14명에서 고식적 치료로 스테로이드를 투여하였는데 9명(64%)에서 임상적인 호전을, 6명(43%)에서 방사선학적인 호전을 결론: 탄분섬유증은 결핵뿐만 아니라...
Chondrosarcomas are malignant tumors of cartilage that rarely involve the sinonasal region, and myxoid chondrosarcoma is a rare histologic variant usually occurs in soft tissue extremities. Although several case reports results small series chondrosarcomas region children available, type extremely rare. We recently experienced low grade involving cavity 10-year-old boy, here we report its radiologic-pathologic findings. In this case, chondroid calcification on CT septal marginal enhancement...
Background There was no practical guideline for the management of patients with central nervous system tumor in Korea past.Thus, Korean Society Neuro-Oncology (KSNO), a multidisciplinary academic society, developed glioblastoma successfully and published it Brain Tumor Research Treatment, official journal KSNO, April 2019.Recently, KSNO World Health Organization (WHO) grade III cerebral glioma adults has been established. MethodsThe Working Group composed 35 medical experts Korea.References...
Our aim was to assess the long-term data regarding efficacy and safety of infliximab (IFX) treatment for refractory Crohn's disease (CD) patients in our tertiary teaching hospital.We have retrospectively analyzed medical records 89 CD who underwent IFX between March 2003 February 2011 at Kyung Hee University Hospital (Seoul, Korea). The primary outcome measurements were rates initial clinical response (CR) 10 weeks after 1st infusion sustained CR end follow-up. Overall adverse events related...