A5052885944- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Management of metastatic bone disease
- Reconstructive Surgery and Microvascular Techniques
- Orthopaedic implants and arthroplasty
- Vascular Tumors and Angiosarcomas
- Cancer Diagnosis and Treatment
- Musculoskeletal synovial abnormalities and treatments
- Cardiac tumors and thrombi
- Orthopedic Infections and Treatments
- Tumors and Oncological Cases
- Soft tissue tumor case studies
- Lymphoma Diagnosis and Treatment
- Bone health and treatments
- Spinal Fractures and Fixation Techniques
- Hematological disorders and diagnostics
- Oral and Maxillofacial Pathology
- Scoliosis diagnosis and treatment
- Bone and Joint Diseases
- Total Knee Arthroplasty Outcomes
- Bone fractures and treatments
- Tuberous Sclerosis Complex Research
- Surgical site infection prevention
- Colorectal and Anal Carcinomas
- Parkinson's Disease and Spinal Disorders
Teikyo University
2021-2025
Montefiore Medical Center
2024
Albert Einstein College of Medicine
2024
Teikyo University Hospital
2024
Saitama Medical University
2012-2023
Saitama International Medical Center
2014-2023
Saitama Medical University Hospital
2019-2020
St Vincent's Hospital
2015-2019
Tokyo Metropolitan Komagome Hospital
2011-2018
Peter MacCallum Cancer Centre
2016
The majority of patients with extremity sarcoma can be surgically treated without amputation. However, limb-salvage surgery for foot sarcomas including the calcaneus remains challenging.A 71-year-old man presented a 5-year history right heel persistent pain. Imaging studies revealed an osteolytic, destructive and highly metabolic lesion in calcaneus. Computed tomography guided core needle biopsy confirmed diagnosis grade 2 chondrosarcoma. A total calcanectomy was performed, defect...
The mainstay of treatment for soft-tissue sarcomas is complete resection with negative surgical margins. However, strategies local control including the frequency adjuvant radiotherapy (RT) and margin differ greatly between Japan other countries, optimal strategy remains controversial. A total 70 patients high-grade sarcoma who underwent surgery 72 enrolled in JCOG0304, were included. primary endpoint was proportion recurrence, we investigated clinicopathological background recurrence cases,...
Abstract This study aimed to compare the oncological results between unplanned excision (UE) and planned (PE) of malignant soft tissue tumor examine impact residual (ReT) after UE. Nonmetastatic sarcomas surgically treated in 1996–2012 were included this study. Disease‐specific survival (DSS), metastasis‐free (MFS), local‐recurrence‐free (LRFS) stratified according location American Joint Committee on Cancer Classification 7th edition stage. Independent prognostic parameters identified by...
Surgical treatment options of femoral metastases include intramedullary nailing (IMN) and endoprosthetic reconstruction (EPR). Previous studies have demonstrated functional oncological advantages EPR over IMN. The purpose this study was to (1) report the durability IMN (2) establish indication for metastases.In 2003-2013, among 186 surgically treated metastasis cases, we retrospectively reviewed 80 consecutive cases in 75 patients, including 14 pathological 66 impending fractures. For...
Bone metastases are the main cause of locomotive syndrome in cancer patients (Cancer Locomo). They should be appropriately managed to improve patients' activities daily living and quality life, especially designated care hospitals (DCCHs). Still, actual involvement orthopedic surgeons managing bone was uncertain. In 2018, an online questionnaire 38 questions used conduct a nationwide survey among orthopaedic training facilities. Eleven were clarify whether actively involved metastasis...
Thanks to recent advancement in cancer treatment, an increasing number of patients are expected live longer with cancer. The ambulatory ability is essential for spend their own independent lives, but locomotive syndrome (LS), a condition reduced mobility due impairment organs, has been seldom examined.This was single-institutional cross-sectional study. Cancer receiving therapy between April 2020 and March 2021 were asked participate. LS classified as stage 0-3, compared performance status...
Abstract Background Approximately 1% of clinically treatable tyrosine kinase fusions, including anaplastic lymphoma kinase, neurotrophic receptor RET proto-oncogene, and ROS proto-oncogene 1, have been identified in soft tissue sarcomas via comprehensive genome profiling based on DNA sequencing. Histologic tumor-specific fusion genes reported approximately 20% sarcomas; however, unlike genes, these fusions cannot be directly targeted therapy. 80% fusion-negative sarcomas, myxofibrosarcoma...
Surgery in combination with radiotherapy (RT) has become the standard of care for most soft tissue sarcomas. The choice between pre- and postoperative RT is controversial. Preoperative associated a 32-35% rate major wound complications (MWC) 16-25% reoperation. role vascularized "flaps" reducing unclear. We report outcomes patients treated preoperative RT, resection, flap reconstruction.122 treatment episodes involving 117 were retrospectively reviewed. All 50.4 Gy external beam radiation....
Chondrosarcoma is the second most common primary malignant bone tumor. In this multicenter study, we sought to evaluate disease-specific survival (DSS) and disease-free (DFS), prognostic factors in patients with dedifferentiated chondrosarcoma (DDCS) or grade 3 (G3CS) Japan. We retrospectively investigated treatment outcomes 62 DDCS 19 G3CS at 15 institutions participating Japanese Musculoskeletal Oncology Group. also clarified significant clinicopathological for oncological outcomes....
11503 Background: We have previously reported long-term follow-up results of the favorable efficacy perioperative chemotherapy with adriamycin plus ifosfamide (AI) for high-grade soft tissue sarcomas (STS) (JCOG0304). also second interim analysis a phase II/III trial to confirm non-inferiority gemcitabine docetaxel (GD) AI STS (JCOG1306) in 2020 ASCO Annual Meeting. This study was terminated at preplanned based on point estimate hazard ratio (HR) being above pre-specified allowable HR 1.61....
Reconstruction after wide resection for a sarcoma involving the knee extensor mechanism is challenging even if tumor small. We report on four consecutive peri-patellar tendon sarcomas treated similarly at single institution. Histological diagnoses were synovial (two cases), clear cell and extraskeletal Ewing’s (one case each). Follow-up periods surgery 18–67 months. All cases underwent pre-operative radiotherapy subsequent surgery. After preoperative including patellar tendon, bone-patellar...
Type 3 internal hemipelvectomy involves resection of the pubis. We report on 2 patients who underwent type hemipelvectomy. One patient developed a bladder hernia, tumour recurrence, and pathological fracture proximal femur. These were resolved with external 7 months later. Another additional fascia lata transplantation to prevent development hernia. Both had stress in contralateral posterior ilium mimicking bone metastasis.
We report a rare case of para-articular osteochondroma the infrapatellar fat pad. A 56-year-old woman presented with 2-year history mild anterior knee pain and hard mass around right knee. Plain radiographs computed tomography revealed trabeculated ossification within performed surgery through an open approach. The was located pad did not communicate joint space or patellar tendon. gross appearance tumor resembled osteochondroma. On microscopic examination, it composed cartilaginous tissue...
Abstract Background The high rate of aseptic loosening cemented stems has led to their frequent use in endoprosthetic reconstruction. However, problems, such as stem breakage and stress shielding at the insertion site, remain. Japanese Musculoskeletal Oncology Group (JMOG) developed Kyocera Modular Limb Salvage System (KMLS) cementless with a unique tapered press-fit short fixation design. This study aimed clarify short-term postoperative outcomes this prosthesis validate Methods One hundred...