A5042560227- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Pituitary Gland Disorders and Treatments
- Glioma Diagnosis and Treatment
- Neurological disorders and treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Facial Trauma and Fracture Management
- Parkinson's Disease Mechanisms and Treatments
- Epilepsy research and treatment
- Advanced MRI Techniques and Applications
- Neuroscience and Neuropharmacology Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Nanoplatforms for cancer theranostics
- Ophthalmology and Eye Disorders
- Dialysis and Renal Disease Management
- Craniofacial Disorders and Treatments
- CNS Lymphoma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Photodynamic Therapy Research Studies
- Glycogen Storage Diseases and Myoclonus
Hospital Clínic de Barcelona
2021-2025
Universitat de Barcelona
2021-2025
Neurosciences Institute
2024
Neurological Surgery
2023
Purpose Spine biomechanics, particularly sagittal balance and spino-pelvic angulation are determinant factors in the understanding of lumbar degenerative disease. These concepts translated into objective measurements progressively being integrated clinical practice. The present study explores them as prognostic patients undergoing microdiscectomy, which could help identify those at higher risk surgical failure. Methods Prospective analysis treated with microdiscectomy ( n = 52) healthy...
Deep brain stimulation has become the standard of care for refractory Parkinson's disease. Neuroimaging advances have led to image-based targeting subthalamic nucleus under general anaesthesia (GA), an approach that renders unnecessary microelectrode recording and tests local conscious sedation (CS). We aimed compare procedures incidents related each anaesthetic approach. Retrospective descriptive comparison deep CS versus G. collected patient procedure data (e.g., comorbidities, difficult...
Introduction Aneurysmal subarachnoid hemorrhage (aSAH) is a rare cause of stroke that poses significant morbidity and mortality, as it affects patients around the age 50 years. While advances in early aneurysm intervention have reduced mortality rates, many still experience poor outcomes due to brain injury (EBI) delayed cerebral ischemia (DCI). This study aims explore characteristics with neurological among status at admission, using comprehensive clinical neuroimaging data. Methods We...
This video presents the transorbital endoscopic resection of a Meckel’s cave lesion, initially suspected as trigeminal schwannoma. A 35-year-old woman with hypoesthesia, pain, and gait instability underwent near-total tumor removal, transient cranial nerve III deficit that resolved completely. Histopathology identified hybrid benign lesion (trigeminal schwannoma/neurofibroma, WHO grade I). minimally invasive technique offers effective while preserving neurological function, making it...
Background: The high recurrence of glioblastoma (GB) that occurs adjacent to the resection cavity within two years diagnosis urges an improvement therapies oriented GB local control. Photodynamic therapy (PDT) has been proposed cleanse infiltrating tumor cells from parenchyma ameliorate short long-term progression-free survival. We examined 5-aminolevulinic acid (5-ALA)-mediated PDT effects as therapeutical treatment and determined optimal conditions for efficacy without causing phototoxic...
BACKGROUND: The endoscopic superior eyelid transorbital route to the skull base is gaining progressive popularity in neurosurgical community. OBJECTIVE: To evaluate anatomy of middle cranial fossa from this novel ventral perspective reach through and show limits for possible safe drilling route. METHODS: Anatomic study was performed; 5 cadaveric specimens (ie, 10 sides) 2 dry skulls 4 were dissected. RESULTS: obtain a functional result, there are boundaries that correspond neurovascular...
Superior eyelid endoscopic transorbital approach (SETOA) is nowadays gaining progressive application in neurosurgical scenarios. Both anatomic and clinical reports have demonstrated the possibility of taking advantage orbital corridor as a minimally invasive route to reach anterior middle cranial fossae manage selected surgical lesions developing these areas. The aim this paper further shed light on other regions skull base seen from perspective, namely, posterior fossa tentorial area,...
Combined endonasal and transorbital multiportal surgery has been recently described for selected skull base pathologies. Nevertheless, a detailed anatomic description quantitative comprehensive study of the areas where these 2 endoscopic routes converge, so-called connection areas, are missing in scientific literature.To identify all structures avenues could be connected combined.Five cadaveric specimens (10 sides) were used dissection. Qualitative analysis each performed.At anterior cranial...
The endoscopic superior eyelid approach is a relatively novel mini-invasive technique that currently investigating for skull base cancers. However, questions remain regarding specific approach-related complications when treating different tumors. This study aims to analyze any surgical occurred in our preliminary consecutive experience, with focus on orbital outcome.
The endoscopic transorbital approach (ETOA) has been demonstrated to be a feasible ventral route the petrous apex. Yet, it pointed as deep and narrow corridor for anterior petrosectomy; particularly, medialization of instruments can become an issue when targeting petroclival area. To overcome this limitation, ETOA with orbital rim removal (ETOA-OR) suggested, but not de facto compared, without rim. This addition could augment surgical exposure freedom movement accessing apex
Postoperative deserved outcomes in acromegalic patients are to normalize serum insulin-like growth factor (IGF-1), reduce the tumoral mass effect, improve systemic comorbidities, and reverse metabolic alterations. Pituitary neuroendocrine tumors (PitNET) characterized present a heterogeneous behavior, hormone (GH)-secreting PitNET is not an exception. Promptly determining which affected by more aggressive essential guide optimal postoperative decision-making process [prognostic-based...
OBJECTIVE The endoscopic superior eyelid transorbital approach has garnered significant consideration and gained popularity in recent years. Detailed anatomical knowledge along with clinical experience allowed refinement of the technique as well expansion its indications. Using bone a consistent reference, authors identified five main pillars that offer access to different intracranial targeted areas for pathologies skull base, aim enhancing understanding accessible through this corridor....
The cavernous sinus (CS) is a demanding surgical territory, given its deep location and the involvement of multiple neurovascular structures. Subjected to recurrent discussion on optimal access, endoscopic transorbital approach has been recently proposed as feasible route for selected lesions in lateral CS. Still, this technique safely evolve consolidate, comprehensive anatomical description involved cranial nerves, dural ligaments, arterial relations needed.
Intraoperative imaging is a chief asset in neurosurgical oncology, it improves the extent of resection and postoperative outcomes. Imaging devices have evolved considerably, particular ultrasound (iUS) magnetic resonance (iMR). Although iUS regarded as more economically convenient yet effective asset, no formal comparison between efficiency iMR oncology has been performed.A cost-effectiveness analysis comparing two single-center prospectively collected surgical cohorts, classified according...
Background: Subarachnoid hemorrhage (SAH) entails high morbidity and mortality rates. Convolutional neural networks (CNN) are capable of generating highly accurate predictions from imaging data. Our objective was to predict in SAH patients by processing initial CT scans using a CNN-based algorithm. Methods: We conducted retrospective multicentric study consecutive cohort with SAH. Demographic, clinical radiological variables were analyzed. Preprocessed baseline scan images used as the input...
Starting from an anatomic study describing the possibility of reaching temporal region through endoscopic transorbital approach, many clinical reports have now demonstrated applicability this strategy when dealing with intra-axial lesions. The aimed to provide both a qualitative description region, as seen perspective, and quantitative analysis amount lobe resection achievable via route.A total four cadaveric heads (eight sides) were dissected at Laboratory Surgical Neuroanatomy (LSNA)...
Objective Spontaneous intracerebral hemorrhage is characterized by high fatality outcomes, even under best medical treatment. Recently, minimally invasive surgical (MIS) evacuation of the hematoma has shown promising results and may soon be implemented in clinical practice. Hereby, we intended to foresee logistic requirements for an early protocol, as well evaluate a real-life implementation model cost-utility two main MIS techniques hemorrhagic stroke (catheter plus thrombolysis...
Risk of rupture in arteriovenous malformations (AVMs) varies considerably among series. Hemodynamic factors, especially within the venous side circuit, seem to be responsible but are not yet well defined. We analyzed tortuosity draining vein as a potential new marker AVMs, and propose simple index predict AVM bleeding.A retrospective analysis angioarchitecture brain AVMs was carried out at our center from 2013 2021, with special attention tortuosity. After univariate analysis, features...
Abstract Background Traditionally, functional neurosurgery relied in stereotactic atlases and intraoperative micro-registration awake patients for electrode placement Parkinson’s disease. Cumulative experience on target description, refinement of MRI, advances imaging has enabled accurate preoperative planning its implementation with the patient under general anaesthesia. Methods Stepwise emphasising planning, verification, transition to asleep-DBS surgery. Conclusion Direct targeting relies...