- Traumatic Brain Injury and Neurovascular Disturbances
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Airway Management and Intubation Techniques
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Cerebrospinal fluid and hydrocephalus
- Thermal Regulation in Medicine
- Dialysis and Renal Disease Management
- Cardiac Arrest and Resuscitation
- Adrenal Hormones and Disorders
- Forensic Toxicology and Drug Analysis
- Intracerebral and Subarachnoid Hemorrhage Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sepsis Diagnosis and Treatment
- Blood transfusion and management
- Gut microbiota and health
- Tracheal and airway disorders
- Cannabis and Cannabinoid Research
- Poisoning and overdose treatments
- Neuroblastoma Research and Treatments
- Alcohol Consumption and Health Effects
- Cerebrovascular and Carotid Artery Diseases
Hospital Clínic de Barcelona
2020-2025
Universitat de Barcelona
2023-2025
Smile Train
2024
Universitat Pompeu Fabra
2022
Erasmus Hospital
2022
Hospital Clínico Universitario de Valencia
2020
Hospital Universitari i Politècnic La Fe
2020
Hospital Universitario de La Princesa
2020
Complejo Hospitalario de Pontevedra
2020
Hospital Del Mar
2018-2020
Importance Blood transfusions are commonly administered to patients with acute brain injury. The optimal hemoglobin transfusion threshold is uncertain in this patient population. Objective To assess the impact on neurological outcome of 2 different thresholds guide red blood cell Design, Setting, and Participants Multicenter, phase 3, parallel-group, investigator-initiated, pragmatic, open-label randomized clinical trial conducted 72 intensive care units across 22 countries. Eligible had...
The optimal hemoglobin (Hb) threshold to trigger red blood cell transfusions (RBCT) in subarachnoid hemorrhage (SAH) patients is unclear. This study evaluated the impact of liberal versus restrictive transfusion strategies on neurological outcome with SAH. a pre-planned secondary analysis "TRansfusion Strategies Acute brain INjured Patients" (TRAIN) study. We included all SAH from original that were randomized receive RBCT when Hb levels dropped below 9 g/dL (liberal group) or 7 (restrictive...
Aneurysmal subarachnoid hemorrhage (aSAH) is a rare cause of stroke that poses significant morbidity and mortality, as it affects patients around the age 50 years. While advances in early aneurysm intervention have reduced mortality rates, many still experience poor outcomes due to brain injury (EBI) delayed cerebral ischemia (DCI). This study aims explore characteristics with neurological among status at admission, using comprehensive clinical neuroimaging data. We analyzed 377 aSAH (WFNS...
There is an overlap between the respiratory, blood and gut microbiomes in patients with acute respiratory distress syndrome. Specific taxa lungs are associated inflammatory response. https://bit.ly/3TdkHd7.
Abstract Intrahospital transfer (IHT), a routine in the management of neurocritical patients requiring imaging or interventions, might affect brain metabolism. Studies about IHT effects using microdialysis (MD) have produced conflicting results. In these studies, only most damaged hemisphere was monitored, and those may not reflect impact on overall metabolism, nor do they address differences between hemispheres. Herein we aimed to quantify effect metabolism by monitoring both hemispheres...
Abstract Hyperglycemia during early brain injury (EBI) period after spontaneous subarachnoid hemorrhage (SAH) is associated with poor outcome, but the underlying physiopathology unknown. This study assessed if hyperglycemia EBI markers of neuroaxonal and whether these biomarkers partially account for association between clinical outcome. Ninety-two SAH patients admitted within 24 h bleeding onset were prospectively included. Glucose levels measured at arrival every 6 72 h. Serum...
Stroke Units (SU) have been suggested as an alternative to Intensive Care units (ICU) for initial admission of low-grade non-aneurysmal spontaneous subarachnoid haemorrhage (naSAH). We hypothesised that the incidence in-hospital complications and long-term clinical outcomes in naSAH patients would be comparable both settings, a cost-minimisation analysis favour use SU.
High levels of procalcitonin (PCT) have been associated with a higher risk mortality in COVID-19 patients. We explored the prognostic role early PCT assessment critically ill patients and whether predictive performance would be influenced by immunosuppression.Retrospective multicentric analysis prospective collected data consecutively admitted to 36 intensive care units (ICUs) Spain Andorra from March June 2020. Adult (>18 years) confirmed available values (<72 hours ICU admission) were...
Abstract Intrahospital transfer (IHT), a routine in the management of neurocritical patients requiring imaging or interventions, might affect brain metabolism. Studies about IHT effects using microdialysis (MD) have produced conflicting results. In these studies, only most damaged hemisphere was monitored, and those may not reflect impact on overall metabolism, nor do they address differences between hemispheres. Herein we aimed to quantify effect metabolism by monitoring both hemispheres...