Leonid Sternik

ORCID: 0000-0001-7180-9286
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About
Contact & Profiles
Research Areas
  • Cardiac Valve Diseases and Treatments
  • Cardiac Structural Anomalies and Repair
  • Cardiac Arrhythmias and Treatments
  • Atrial Fibrillation Management and Outcomes
  • Mechanical Circulatory Support Devices
  • Infective Endocarditis Diagnosis and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac and Coronary Surgery Techniques
  • Transplantation: Methods and Outcomes
  • Aortic Disease and Treatment Approaches
  • Cardiac pacing and defibrillation studies
  • Cardiac Arrest and Resuscitation
  • Cardiac Imaging and Diagnostics
  • Coronary Interventions and Diagnostics
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiovascular Issues in Pregnancy
  • Cardiac electrophysiology and arrhythmias
  • Viral Infections and Immunology Research
  • Acute Myocardial Infarction Research
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Cardiac tumors and thrombi
  • Extracellular vesicles in disease
  • Cardiovascular Function and Risk Factors
  • Kawasaki Disease and Coronary Complications

Sheba Medical Center
2015-2024

Tel Aviv University
2014-2024

Poriya Medical Center
2020-2022

Society of Thoracic Surgeons
2020

Assaf Harofeh Medical Center
2013

Leoni (Germany)
2013

East Riding of Yorkshire Council
2010

Weizmann Institute of Science
2009

Abbott (Sweden)
2009

Mayo Clinic
2002-2005

14 Fr delivery system.Single-or double-curve configuration.Jellyfishshaped nitinol wire frame.Recapturable.160 µm PET fabric sealing skirt at atrial side of device lobe.10 fixation anchors distal to skirt.Device diameter: 21-33 mm.17-31 mm proximal landing zone.Reproducible results; supported by solid scientific data (2 RCTs).Requires deep intubation LAA with sheath for deployment.

10.4244/eijy19m08_01 article EN EuroIntervention 2020-01-01

Background: The role of epicardial fat (eFat)-derived extracellular vesicles (EVs) in the pathogenesis atrial fibrillation (AF) has never been studied. We tested hypothesis that eFat-EVs transmit proinflammatory, profibrotic, and proarrhythmic molecules induce myopathy fibrillation. Methods: collected eFat specimens from patients with (n=32) without AF (n=30) during elective heart surgery. samples were grown as organ cultures, culture medium was every 2 days. then isolated purified medium,...

10.1161/circulationaha.120.052009 article EN Circulation 2021-04-01

Pulmonary edema is a severe and often life-threatening condition. The diagnosis of pulmonary its quantification have great clinical significance yet can be difficult. A new technique based on thermodilution measurement using single indicator has recently been developed (PiCCO, Pulsion Medical Systems, AG Germany). This method allows the extravascular lung water thus quantify degree edema. not compared with gold standard, gravimetric water. Therefore, objective this study was to determine...

10.1097/01.ccm.0000130995.18334.8b article EN Critical Care Medicine 2004-06-25

10.1016/j.jacc.2006.09.039 article EN publisher-specific-oa Journal of the American College of Cardiology 2007-01-23

Background— The identification and isolation of human cardiac progenitor cells (hCPCs) offer new approaches for myocardial regeneration repair. Still, the optimal source influence patient characteristics on their number remain unclear. Using a novel method to isolate cells, we aimed define association between characteristics. Methods Results— We developed that produced viable (7×10 6 ±6.53×10 5 /g) from various tissue samples obtained during heart surgery or endomyocardial biopsies (113 94...

10.1161/circulationaha.109.849588 article EN Circulation 2009-12-08

The repeated waves of the COVID-19 pandemic have highlighted necessity to optimize vaccine responses in immunocompromised populations. We investigated safety and immunogenicity a third, booster, dose Pfizer BNT162b2 heart transplant (HT) patients.

10.1016/j.healun.2021.08.010 article EN other-oa The Journal of Heart and Lung Transplantation 2021-08-28

Background Severe lung injury with the development of acute respiratory distress syndrome (ARDS) is a serious complication cardiac surgery. The aim this study was to determine incidence, risk factors, and mortality ARDS following Methods We retrospectively analyze data in period between January 2005 March 2013. Results Of 6069 patients who underwent surgery during period, 37 developed postoperative period. incidence 0.61%, 40.5% (15 patients). Multivariate regression analysis identified...

10.1111/jocs.12264 article EN Journal of Cardiac Surgery 2013-12-03

Type 2 diabetes mellitus (DM) is a frequent co-morbidity among patients undergoing coronary artery bypass grafting (CABG) surgery. The aim of this study was to evaluate the impact DM on early- and long-term outcomes who underwent isolated CABG. We performed an observational cohort in large tertiary medical center over period 11 years. All data from had undergone CABG surgery between 2004 2014 were obtained our departmental database. population included 2766 divided into two groups: Group I...

10.1186/s12933-018-0796-7 article EN cc-by Cardiovascular Diabetology 2018-11-29

<b><i>Background:</i></b> Lung injury with development of the acute respiratory distress syndrome (ARDS) is a serious complication which can occur after major surgery, including cardiac surgery. <b><i>Objective:</i></b> The aim our study was to compare prevalence, risk factors, and mortality ARDS following surgery according American-European Consensus Conference (AECC) definition new Berlin ARDS. <b><i>Methods:</i></b>...

10.1159/000495511 article EN Respiration 2019-01-01

Background We aimed to evaluate the graft patency rate following coronary artery bypass grafting (CABG) left anterior descending (LAD) with proximal myocardial bridging (MB). While MB is generally a benign abnormality, ischemia, stunning, and sudden death have been reported. In symptomatic patients LAD systolic compression of >50%, positive for ischemic noninvasive testing noneffective optimal medical therapy, intervention could be indicated. Few studies CABG in The influence high flow...

10.1111/jocs.12101 article EN Journal of Cardiac Surgery 2013-04-10

Abstract Background Type 2 diabetes mellitus (DM) is a risk factor for cardiovascular diseases and common among patients undergoing coronary artery bypass grafting (CABG) surgery. The main objective of our study was to investigate the impact DM type 2, its treatment subgroups, on short- long-term mortality in with acute syndrome (ACS) who undergo CABG. Methods included 1307 enrolled from biennial Acute Coronary Syndrome Israeli Survey between 2000 2016, were hospitalized ACS underwent Of...

10.1186/s12933-020-01069-6 article EN cc-by Cardiovascular Diabetology 2020-06-13

In March 2020, COVID-19 was announced as a global pandemic. The first patient connected to an ECMO device in Israel during that time. Since then, over 200 patients have required support due infection. present study is multi-institutional analysis of all requiring veno-venous (VV) Israel. aim characterize and compare the survivors deceased well establish risk factors for mortality.This retrospective conducted from 2020 2021 eleven twelve centers operating All on VV were included cohort....

10.3390/vaccines11010108 article EN cc-by Vaccines 2023-01-01

Abstract Background Cardiac allograft vasculopathy (CAV) is a major cause of morbidity and mortality following heart transplantation (HT). Reduced cardiovascular have been reported in non-HT patients treated with metformin. Given the high prevalence type 2 diabetes mellitus (T2DM) HT patients, we investigated association between metformin therapy outcomes after HT. Methods The study population comprised 103 DM who had undergone 1994 2018 were prospectively followed-up. We excluded from 1...

10.1186/s12933-019-0925-y article EN cc-by Cardiovascular Diabetology 2019-09-16
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