Rafael Kuperstein

ORCID: 0000-0002-1892-9403
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About
Contact & Profiles
Research Areas
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Function and Risk Factors
  • Cardiac Structural Anomalies and Repair
  • Cardiac Imaging and Diagnostics
  • Atrial Fibrillation Management and Outcomes
  • Cardiovascular Issues in Pregnancy
  • Infective Endocarditis Diagnosis and Management
  • Cardiac tumors and thrombi
  • Cardiac pacing and defibrillation studies
  • Cardiac Arrhythmias and Treatments
  • Heart Failure Treatment and Management
  • Pulmonary Hypertension Research and Treatments
  • Cardiomyopathy and Myosin Studies
  • Aortic Disease and Treatment Approaches
  • Congenital Heart Disease Studies
  • Cardiovascular Effects of Exercise
  • Cardiovascular Disease and Adiposity
  • Viral Infections and Immunology Research
  • Pericarditis and Cardiac Tamponade
  • Acute Myocardial Infarction Research
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Coronary Artery Anomalies
  • Kawasaki Disease and Coronary Complications
  • Connective tissue disorders research
  • Mechanical Circulatory Support Devices

Sheba Medical Center
2015-2024

Tel Aviv University
2015-2024

Creative Commons
2017

Soroka Medical Center
2016

Kaplan Medical Center
2016

Rabin Medical Center
2016

Brigham and Women's Hospital
2013

Harvard University
2013

University of Rochester Medical Center
2013

Shaare Zedek Medical Center
2009

There are limited data regarding factors affecting outcomes among acute coronary syndrome (ACS) patients presenting with varying degrees of left ventricle (LV) dysfunction. We aimed to identify associated mortality according LV ejection fraction (LVEF) at 1st admission in ACS patients. A total 8983 prospectively enrolled the Acute Coronary Syndrome Israeli Survey (2000–2010) were categorized their LVEF admission: severe dysfunction (LVEF < 30% [n = 845]), mild-moderate 30%–49% 4470]);...

10.1097/md.0000000000006226 article EN cc-by-nc Medicine 2017-03-01

Rapid ventricular pacing (RVP) is used commonly during transcatheter aortic valve replacement (TAVR). Little known about the safety and clinical consequences of this step. The aim study was to assess impact RVP on immediate long-term outcomes in a large cohort non-selected TAVR patients.

10.1161/jaha.118.009038 article EN cc-by-nc-nd Journal of the American Heart Association 2018-07-09

Diabetes mellitus (DM) aggravates the clinical features of ischaemic and hypertensive heart diseases worsens prognosis failure patients. Hypertrophic cardiomyopathy (HCM) diabetes coexist fairly frequently in elderly patients but impact DM on phenotype HCM is yet unknown. We sought to describe if predominant exist independently HCM.We reviewed characteristics 937 patients, age ≥40, diagnosed with HCM, from two tertiary medical centres Spain Israel. A propensity score matched cohort 294 was...

10.1093/eurheartj/ehy625 article EN European Heart Journal 2018-09-19

Abstract Background The safety and impact of sodium glucose transporter 2 inhibitors (SGLT2‐I) in patients with left ventricular assist devices (LVAD) are unknown. Methods A retrospective analysis all consecutive who underwent LVAD Heart Mate 3 (HM3) implantation at a single medical center received SGLT2‐I therapy following surgery was conducted. parameters, therapy, laboratory tests, echocardiography, right heart catheterization (RHC) study results were recorded compared before after...

10.1111/aor.14733 article EN Artificial Organs 2024-02-26

Recent studies suggest that angiogenic imbalance during pregnancy may lead to acute peripartum cardiomyopathy (PPCM). We propose and residual cardiac dysfunction exist even after recovery from PPCM.Twenty-nine women at least 12 months presentation with PPCM, who exhibited of left ventricular (LV) ejection fraction (≥50%), were included in the study (mean age 35±6 years, LV 61.0±3.9%). The number circulating endothelial progenitor cells (EPCs) plasma levels proangiogenic vascular growth...

10.1161/circheartfailure.116.003349 article EN Circulation Heart Failure 2016-11-01

Heart failure with improved ejection fraction (HFimpEF) is a recently recognized entity presenting diagnostic and therapeutic challenge. Our aim was to characterize the profile of HFimpEF patients evaluate predictors for EF lack improvement among heart reduced (HFrEF) patients.

10.3389/fcvm.2024.1378955 article EN cc-by Frontiers in Cardiovascular Medicine 2024-07-17

Background— Left atrial volume (LAV) is an important marker of heart failure (HF) severity. We hypothesized that LAV independently correlates with clinical outcomes in patients who receive cardiac resynchronization therapy a defibrillator (CRT-D) and can be used for improved risk assessment this population. Methods Results— The benefit CRT-D versus defibrillator-only reducing the HF or death was assessed by (dichotomized at upper quartile &gt;52 mL/m 2 ) among 1785 enrolled Multicenter...

10.1161/circheartfailure.113.000748 article EN Circulation Heart Failure 2013-12-18

Identification and quantification of segmental left ventricular wall motion abnormalities on echocardiograms is paramount clinical importance but still performed by a subjective visual method. We constructed an automatic tool for assessment based longitudinal strain.Echocardiograms 105 patients (3 apical views) were blindly analyzed 12 experienced readers. Visual scores (VSS) peak systolic strain assigned to each 18 segments per patient. Ranges that best fit VSS (by receiver operating...

10.1161/circimaging.108.841874 article EN Circulation Cardiovascular Imaging 2009-11-20

Background. Tricuspid valve regurgitation (TR) after orthotopic heart transplantation (OHT) is common. The aims of this study were to determine the prevalence TR OHT, examine correlation between its development and various variables, outcomes. Methods. All 163 OHT patients who followed up 1988 2009 for a minimal period 12 months divided into those with no TR/mild at least mild-moderate TR, as assessed by doppler echocardiography. These groups compared regarding preoperative hemodynamic...

10.1155/2012/120702 article EN cc-by Journal of Transplantation 2012-01-01

Left ventricular (LV) diastolic dysfunction (LVDD) is a well-established and early echocardiographic characteristic of diabetic cardiomyopathy. However, there are limited data on the association between impaired fasting glucose (IFG) LVDD.To determine whether IFG associated with LVDD among middle age adults.Amongst 3781 subjects screened in an annual health survey program referred for echocardiogram, 2971 individuals without LV systolic or valvular heart disease were selected. Mean study...

10.1186/s12933-015-0282-4 article EN cc-by Cardiovascular Diabetology 2015-09-14

Amyloidosis due to the transthyretin Ser77Tyr mutation (ATTRS77Y) is a rare autosomal-dominant disorder, characterized by carpal-tunnel syndrome, poly- and autonomic-neuropathy, cardiomyopathy. However, related symptoms signs are often nonspecific confirmatory tests required. We describe age frequency of early diagnostic features among individuals Jewish Yemenite descent in Israel.Records carriers were retrospectively reviewed. ATTRS77Y diagnosis was defined presence amyloid tissue and/or...

10.1002/acn3.51741 article EN cc-by Annals of Clinical and Translational Neurology 2023-02-11

Background The diagnosis of a left ventricular (LV) thrombus in patients with ST-segment elevation myocardial infarction (STEMI) remains challenging. aim the current study is to characterize clinical predictors for LV formation, as detected by cardiac magnetic resonance imaging (CMRI). Methods We retrospectively evaluated 337 consecutive STEMI patients. All underwent transthoracic echocardiography (TTE) and CMRI during their index hospitalization. developed novel risk stratification model...

10.3389/fcvm.2023.1275390 article EN cc-by Frontiers in Cardiovascular Medicine 2024-01-16
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