- Amyloidosis: Diagnosis, Treatment, Outcomes
- Aortic Disease and Treatment Approaches
- Cardiovascular Issues in Pregnancy
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Inflammatory Bowel Disease
- Pulmonary Hypertension Research and Treatments
- Fluoride Effects and Removal
- Parathyroid Disorders and Treatments
- Cardiomyopathy and Myosin Studies
- Dermatological and Skeletal Disorders
- Peptidase Inhibition and Analysis
- Heart Failure Treatment and Management
- Platelet Disorders and Treatments
- Takotsubo Cardiomyopathy and Associated Phenomena
- Blood Coagulation and Thrombosis Mechanisms
- Zoonotic diseases and public health
- Congenital Heart Disease Studies
- Angiogenesis and VEGF in Cancer
- Aortic aneurysm repair treatments
- Microscopic Colitis
- Coronary Artery Anomalies
- Protein Kinase Regulation and GTPase Signaling
- Autoimmune and Inflammatory Disorders Research
- Adipokines, Inflammation, and Metabolic Diseases
Tel Aviv University
1983-2024
Meir Medical Center
2024
Kaplan Medical Center
2011-2022
Sheba Medical Center
2016
Soroka Medical Center
2016
Rabin Medical Center
2016
Hadassah
2012
Tel Aviv Sourasky Medical Center
2008
Recent studies suggest that angiogenic imbalance during pregnancy may lead to acute peripartum cardiomyopathy (PPCM). We propose and residual cardiac dysfunction exist even after recovery from PPCM.Twenty-nine women at least 12 months presentation with PPCM, who exhibited of left ventricular (LV) ejection fraction (≥50%), were included in the study (mean age 35±6 years, LV 61.0±3.9%). The number circulating endothelial progenitor cells (EPCs) plasma levels proangiogenic vascular growth...
As opposed to regular C-reactive protein (CRP) assays, the introduction of high-sensitivity ones has enabled us detect low grade inflammation in patients with inflammatory bowel disease (IBD). We addressed subject degree correlation between concentration CRP (hs-CRP) and IBD activity score.Included were 90 Crohn's (CD), 70 ulcerative colitis (UC) 160 controls. Disease was determined using CD index (CDAI) for Mayo score UC. The Dade Boering BNII Nephelometer used determine hs-CRP...
Transthyretin cardiac amyloidosis (ATTR-CA) is an increasingly recognized cause of heart failure (HF) with preserved left ventricular ejection fraction (LVEF), typically presenting as restrictive cardiomyopathy. The potential co-existence ATTR-CA systolic has not been studied. aim this study to describe the prevalence and its clinical characteristics in HF patients reduced LVEF.
Aortic regurgitation (AR) is a condition associated with volume overload, causing left-ventricular (LV) remodeling, eccentric LV hypertrophy and eventually heart failure. remodeling AR regulated by mechanical stress, neurohormonal activation, inflammation oxidative stress. Since anti-oxidized low-density lipoprotein (LDL) antibodies (Abs) are measurable marker of we hypothesized that an increased level circulating oxidized LDL (oxLDL) Abs may be related to the left ventricle in patients...
It is not clear whether Crohn's disease patients in clinical remission (Crohn's activity index<150) display normal concentrations of inflammation sensitive biomarkers. Our goal this work was to explore the intensity microinflammatory response a group remission.High sensitivity C-reactive protein, quantitative fibrinogen, erythrocyte sedimentation rate as well platelet and leukocyte counts were examined 76 with 228 matched controls.Crohn's displayed statistically significant (p<0.001)...
Endothelial progenitor cells (EPCs) have a role in the repair of endothelial surfaces after injury. Reduced numbers EPCs are related to dysfunction and adverse clinical events, suggesting that injury absence sufficient by circulating promotes progression vascular disease or valvular disorder. The aim present study was assess number patients with aortic valve regurgitation (AR).We assessed apoptotic 31 significant AR compared them 30 who had similar risk factors no disease. were flow...
Takotsubo cardiomyopathy (TCM) is characterized by transient left ventricle dysfunction.A residual cardiac and endothelial dysfunction present in patients who recovered from TCM.In this single-center prospective study, with prior TCM were included followed for 6.4 ± 1.6 years. All underwent comprehensive function assessment, including tissue Doppler imaging (TDI) 2-dimensional strain (2DS) echocardiography at their first visit. The number of circulating progenitor cells levels proangiogenic...
(1) Background: Immunoglobulin gamma subclass 4 (IgG4) is a serum protein belonging to the immunoglobulin superfamily. It has central role in certain immune-mediated conditions defined as IgG4-related disease. There paucity of data regarding potential association IgG4 and cardiovascular diseases. Our aim study levels patients with ischemic non-ischemic dilated cardiomyopathy (DCM). (2) Methods: DCM were included this study. Non-ischemic was left ventricular ejection fraction (LVEF) < 40%...
Abstract Background Anomalous origin of the left coronary artery (LCA) from pulmonary (PA) (ALCAPA) is a rare congenital abnormality. We present case an ALCAPA in 25-year-old man. Case summary A male with no past medical history was admitted to our intensive cardiac care unit after sudden arrest due ventricular fibrillation and suspected acute syndrome. After being treated shock by automated external defibrillator, electrocardiogram (ECG) demonstrated sinus tachycardia antero-lateral...
Abstract Industries that use fluoride‐containing materials are usually aware of their toxicity and adopt adequate medical measures. It has been found workers in factories who have not considered as subjected to fluorine hazard therefore controlled had significantly elevated urinary fluoride levels. Most a medically fertilizer plant normal Maintenance were higher values, up 12 mg/liter.
ABSTRACT Clinical Development Phases I‐III Regulatory, Quality, Manufacturing Pregnancy‐associated thrombosis is an important cause of morbidity and mortality during pregnancy. All anticoagulation options are associated with risks benefits. Thus, although therapy component the management thrombotic complications in pregnancy, it fetal maternal complications. Therefore, pregnancy poses a serious therapeutic dilemma for both physicians their patients. This review summarizes available data on...
BackgroundThe most common cause of pulmonary hypertension (PH) in developed countries is left heart disease (LHD, group 2 PH). The development PH failure (HF) patients indicative worse outcomes.ObjectiveThe aim this study was to evaluate the long term outcomes HF with a national long-term registry.MethodsStudy included 9 cardiology centers across Israel between 01/2013–01/2015, 12-month clinical follow-up and 24-month mortality follow-up. Patients were age ≥18 years old pre-inclusion due...