A5089582674- Algal biology and biofuel production
- Lipid metabolism and biosynthesis
- Atmospheric chemistry and aerosols
- Photosynthetic Processes and Mechanisms
- Air Quality Monitoring and Forecasting
- Microbial Metabolites in Food Biotechnology
- Air Quality and Health Impacts
- Seaweed-derived Bioactive Compounds
- Marine Bivalve and Aquaculture Studies
- Marine and coastal ecosystems
- Studies on Chitinases and Chitosanases
- Food Quality and Safety Studies
- Coral and Marine Ecosystems Studies
- Radioactivity and Radon Measurements
- Pacific and Southeast Asian Studies
- Advanced Graph Neural Networks
- Heavy metals in environment
- Chemical and Physical Properties in Aqueous Solutions
- Lipid Membrane Structure and Behavior
- Enzyme Production and Characterization
- Microbial Natural Products and Biosynthesis
- Smoking Behavior and Cessation
- Behavioral Health and Interventions
- Food composition and properties
- Medical Imaging Techniques and Applications
Second Affiliated Hospital of Fujian Medical University
2025
Fujian Medical University
2025
Shandong First Medical University
2024
Academy of Medical Sciences
2024
Shandong Tumor Hospital
2024
Fujian Institute of Oceanography
2021-2024
Ministry of Natural Resources
2021-2024
Ministry of Natural Resources
2023-2024
China National Rice Research Institute
2013-2017
State Key Laboratory of Rice Biology
2013-2017
Abstract Background The hydrolysis and transphosphatidylation of phospholipase D (PLD) play important roles in the interconversion phospholipids (PLs), which has been shown to profoundly impact lipid metabolism plants. In this study, effect PLD1 gene Schizochytrium limacinum SR21 ( S. SR21) on was investigated. Results knockout had little cell growth production, but it significantly improved percentage polyunsaturated fatty acids lipids, docosahexaenoic acid (DHA) content increased by 13.3%...
A cross-sectional survey was conducted to investigate the differences in preferences, gateway effects, and potential motivations for e-cigarette use among different genders of users China, thereby providing ideas development public prevention intervention measures e-cigarettes. This study adopted a combination online web questionnaires offline distribution 640 by snowball sampling convenience China 2023. We used Potential E-Cigarette Dependence Scale, Preference General Information Scale...
The polyunsaturated fatty acid (PUFA) metabolism of Schizochytrium, an excellent oil-producing microorganism, is closely related to phosphatidylcholine (PC) synthesis, which favors the migration and accumulation docosahexaenoic (DHA). Phosphocholine cytidylyltransferase (CCT), a key enzyme involved in PC profoundly impacts lipid plants; however, few studies have focused on CCT microorganisms. We investigated effects overexpression Schizochytrium sp. slightly inhibited cell growth, but...
How organisms cope with coldness and high pressure in the hadal zone remains poorly understood. Here, we sequenced assembled genome of sea cucumber Paelopatides sp. Yap quality explored its potential mechanisms for deep-sea adaptation. First, expansion ACOX1 rate-limiting enzyme DHA synthesis pathway, increased content phospholipid bilayer, positive selection EPT1 may maintain cell membrane fluidity. Second, three genes translation initiation factors two ribosomal proteins underwent...
Abstract Background Menaquinones are constituents of prokaryote cell membranes where they play important functions during electron transport. Menaquinone profiles strongly recommended for species classification when proposing a new Actinomycetes taxon. Presently, the most widely used methods to determine menaquinones based on freeze-dried cells. Taxonomic research in our lab has revealed that menaquinone concentrations low some genus Microbacterium , leading difficulties identifying...
Abstract Aerosols are a significant source of dissolved black carbon (DBC) in the ocean. However, how anthropogenic activities, including fossil fuel (FF) burning and human‐initiated biomass (BB), would affect seasonal variations concentration condensation degree aerosol DBC was not well constrained. To fill this knowledge gap, we collected 33 samples from December 2018 to September 2019 at southeast coastal site China. Concentrations DBC, water‐soluble organic (WSOC), elemental (EC) were...
Abstract Ceramidases are a group of enzymes that catalyse hydrolysis ceramides to generate fatty acid and sphingosine. In this study, we report the cloning characterization rice small brown planthopper L aodelphax striatellus neutral ceramidase ( nCDase ), LsnCer . was identified by sequencing transcriptome is protein 717 amino acids with predicted molecular weight 79.3 kDa. Similarly other known nCD ases, optimum pH for 8.0 temperature 37 ° C its in vitro activity. activity inhibited Zn 2+...
The hyphenation of ion mobility spectrometry with high-resolution mass has been widely used in the characterization various metabolites. Nevertheless, such a powerful tool remains largely unexplored natural products research, possibly mainly due to lack available compounds. To evaluate ability collision cross-sections (CCSs) characterizing compounds, especially isomeric products, here we measured and compared traveling-wave IMS-derived nitrogen CCS values for 75 marine-derived aphidicolanes....
<title>Abstract</title> Background As a key rate-limiting enzyme in the glycolytic pathway of cells, aldolase affects distribution intracellular carbon flux and determines overall ability subsequent cell metabolism, which are mainly reported medical related researches, but rarely involved microorganisms. In this study, gene <italic>Schizochytrium limacinum</italic> SR21 (<italic>ALDOA</italic>) was knocked out to explore effect regulating on growth lipid synthesis. Results The knockout...
As a key rate-limiting enzyme in the glycolytic pathway of cells, aldolase affects distribution intracellular carbon flux and determines overall ability subsequent cell metabolism, which are mainly reported medical related researches, but rarely involved microorganisms. In this study, gene Schizochytrium limacinum SR21 (ALDOA) was knocked out to explore effect regulating on growth lipid synthesis. The knockout ALDOA showed an adverse total lipids production, decreased by 9.6% 23.2%,...
<title>Abstract</title> Purpose This study aimed to investigate whether dual layer detector energy CT (DECT) quantitative parameters and clinical features could predict pathological complete response(pCR) for esophageal squamous cell carcinoma (ESCC) patients who received neoadjuvant chemoradiotherapy (nCRT). Material methods retrospective recruited local advanced ESCC underwent nCRT followed by surgical treatment from December 2019 January 2023. According pCR status (no visible cancer cells...
Abstract The neutral sphingomyelinase (nSMase) 1 homologue gene LsSMase was cloned from Laodelphax striatellus , a direct sap‐sucker and virus vector of gramineous plants, expressed via Bac to baculovirus expression system. LsSMase‐enhanced green fluorescent protein fusion located in the endoplasmic reticulum similar manner mammalian nSMase 1. biochemical properties were determined detail. optimal pH temperature for recombinant 8 37 °C, respectively. an Mg 2+ or Mn dependent enzyme, but...
Abstract Background: The hydrolysis and transphosphatidylation of phospholipase D (PLD) play important roles in the interconversion phospholipids (PLs), which has been shown to profoundly impact lipid metabolism plants. In this study, effect PLD1 gene Schizochytrium limacinum SR21 on metabolismwas investigated. Results : knockout had little cell growth production, but it significantly improved percentage polyunsaturated fatty acids lipids, docosahexaenoic acid (DHA) content increased by...